Briel Communication : Location by Immunoelectron Microscopy of Carcinoembryonic Antigen on Cultured Adenocarcinoma Cells 2

1975 ◽  
Vol 55 (4) ◽  
pp. 797-799 ◽  
Author(s):  
Ronald B. Herberman ◽  
Tadao Aoki ◽  
Grace Cannon ◽  
Margaret Liu ◽  
Macie Sturm
Keyword(s):  
Carcinoembryonic Antigen ◽  
Immunoelectron Microscopy ◽  
Adenocarcinoma Cells

scholarly journals Diagnosis of malignant effusion using cell block and immunohistochemistry

2019 ◽  
Vol 7 (9) ◽  
pp. 3556
Author(s):  
Bhavna Gamit ◽  
Deepshikha Dave ◽  
Neha Shahu
Keyword(s):  
Carcinoembryonic Antigen ◽  
Epithelial Membrane Antigen ◽  
Early Stage ◽  
Abdominal Distension ◽  
Mesothelial Cells ◽  
Cell Block ◽  
Malignant Effusion ◽  
Adenocarcinoma Cells ◽  
Signet Ring ◽  
Atypical Cells

The distinction between reactive mesothelial and adenocarcinoma cells specially signet ring type in serous effusions may be very difficult based only on morphological features particularly in early stage. Reactive mesothelial cells show varying degree of cytological atypia hence posing difficulty in differentiating it from adenocarcinoma cells. We report a case of 45 year old female patient presented with abdominal distension. Patient was an operated case of adenocarcinoma of stomach. Smears prepared from ascitic fluid and cell block shows large number of reactive mesothelial cells and few atypical cells. Atypical cells were immunoreactive for cytokeratin, epithelial membrane antigen and carcinoembryonic antigen. These confirmed the presence of malignant epithelial cells so we reported it as a malignant effusion.

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