Protein G-gold immunoelectron microscopy of colon carcinoma: The effect of tumor differentiation on carcinoembryonic antigen immunostaining

1988 ◽  
Vol 49 (3) ◽  
pp. 305-315 ◽  
Author(s):  
Kinji Shirota ◽  
Hassmig Minassian ◽  
Serge Jothy
Keyword(s):  
Carcinoembryonic Antigen ◽  
Colon Carcinoma ◽  
Immunoelectron Microscopy ◽  
Protein G ◽  
Tumor Differentiation

Discrepancies in carcinoembryonic antigen measurements: survey and control values vs values for patients.

1987 ◽  
Vol 33 (4) ◽  
pp. 563-566 ◽  
Author(s):  
G G Klee ◽  
L A Dodge ◽  
G Reynoso
Keyword(s):  
Tissue Culture ◽  
Carcinoembryonic Antigen ◽  
Enzyme Immunoassay ◽  
Colon Carcinoma ◽  
Proficiency Testing ◽  
Analytical Methods ◽  
Test Results ◽  
And Control ◽  
The Relationship ◽  
Metastatic Colon Carcinoma

Abstract We analyzed the carcinoembryonic antigen (CEA) test results reported in the College of American Pathologists' (CAP) surveys to determine the relationship between the source of CEA used to manufacture the survey specimens and the discrepancies among analytical methods. With the 1983 survey specimens, which were prepared from metastatic colon carcinoma, laboratories using Roche RIA with Clinetics columns reported results that were only one-half the values reported by laboratories using the Abbott polyclonal enzyme immunoassay. With the 1984 specimens, prepared from a different metastatic colon carcinoma, and the 1985 specimens, prepared from a tissue-culture source of CEA, the Roche results were about one-sixth as large as the Abbott results. These differences are larger than the reported assay differences for patients' specimens. In addition, twofold proportional differences were found when survey and control specimens were tested with different lots of Abbott polyclonal reagent, whereas only random differences were found with 102 patients' specimens. Evidently, assay systems perform differently with proficiency-testing and control specimens than with patients' specimens.

Briel Communication : Location by Immunoelectron Microscopy of Carcinoembryonic Antigen on Cultured Adenocarcinoma Cells 2

1975 ◽  
Vol 55 (4) ◽  
pp. 797-799 ◽  
Author(s):  
Ronald B. Herberman ◽  
Tadao Aoki ◽  
Grace Cannon ◽  
Margaret Liu ◽  
Macie Sturm
Keyword(s):  
Carcinoembryonic Antigen ◽  
Immunoelectron Microscopy ◽  
Adenocarcinoma Cells

Field Effect of Human Colon Carcinoma on Normal Mucosa: Relevance of Carcinoembryonic Antigen Expression

Tumor Biology ◽  
1996 ◽  
Vol 17 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Serge Jothy ◽  
Barbara Slesak ◽  
Antonina Hartozinska ◽  
Jadwiga Lapinska ◽  
Jolanta Adarniak ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Colon Carcinoma ◽  
Field Effect ◽  
Antigen Expression ◽  
Human Colon ◽  
Normal Mucosa ◽  
Human Colon Carcinoma
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