scholarly journals Multiple caecal granular cell tumours—a case report

2021 ◽  
Vol 2021 (9) ◽  
Author(s):  
Kar Yin Fok ◽  
Chow Heok P’Ng ◽  
Hema Mahajan ◽  
Martijn Pieter Gosselink ◽  
Toufic El-Khoury
Keyword(s):  
Patient Management ◽  
Granular Cell ◽  
Right Hemicolectomy ◽  
Benign Neoplasms ◽  
Cellular Atypia ◽  
Neural Origin ◽  
Granular Cell Tumours ◽  
Benign Nature ◽  
Submucosal Lesion ◽  
Multiple Nodules

Abstract Granular cell tumours (GCTs) are generally benign neoplasms, which are believed to be of neural origin. They are uncommon in the gastrointestinal tract. They are rarely found in the colon and even more rarely found to be multiple. We present a case of a man who underwent a right hemicolectomy for a submucosal lesion and polyps and was found to have multiple nodules diagnosed as caecal GCTs with cellular atypia. While uncommon, this case shows it remains an important differential due to implications for patient management, given the often benign nature of disease.

scholarly journals Granular Cell Tumour of The Vulva: A Case Report

1970 ◽  
Vol 3 (1) ◽  
pp. 28-30
Author(s):  
SM Khodeza ◽  
Nahar Begum ◽  
Nishat Begum
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Benign Lesion ◽  
Granular Cell ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Duct Cyst ◽  
Clinical Presentations ◽  
Neural Origin ◽  
Granular Cell Tumours

Vulvar granular cell tumours are uncommon neoplasms of neural origin. The clinical presentations, surgical findings and histology of Granular Cell Tumour (GCT) of the vulva in a 50 year old lady is presented. Although rare, this benign lesion must be considered in the differential diagnosis of the labia majora masses, such as Bartholin,s duct cyst, Lipoma, Papilloma, Hydradenoma and Fibroma. DOI: http://dx.doi.org/10.3329/akmmcj.v3i1.10111 AKMMCJ 2012; 3(1): 28-30

scholarly journals Malignant Clinical Presentation of a Benign Granular Cell Tumor of Breast in a Patient with Previously Treated Contralateral Invasive Ductal Carcinoma

2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Deniz Tural ◽  
Emre Akar ◽  
Tülin Öztürk ◽  
Hande Turna ◽  
Süheyla Serdengeçti
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Granular Cell Tumor ◽  
Ductal Carcinoma ◽  
Subcutaneous Tissue ◽  
Granular Cell ◽  
Cell Tumor ◽  
S 100 ◽  
Neural Origin ◽  
Benign Nature ◽  
Previously Treated

GCT is a rare neoplasm and usually shows the benign character. GCT can occur in any body site and may be multifocal. The most common involved site is tongue which accounts for nearly 30% of all cases but skin and subcutaneous tissue are also affected frequently. Breast is an unusually involved site and accounts for 6% of all GCTs. The histiogenesis of GCT is still controversial but further investigations and immunohistochemical examinations were exposed to neural origin and the tumor is thought to be derived from Schwann cells of peripheral nerves. Generally used technique to diagnose GCT is the positivity of S-100 immunohistochemical staining. Despite its benign nature, GCT may mimic breast carsinoma clinically and radiologically and easily be misdiagnosed for breast cancer. We herein report a case of granular cell tumor that arose in a 56 year-old female patient who previously had been treated from an invasive ductal carcinoma in contralateral breast.

scholarly journals Granular Cell Tumours: A Rare Entity in the Musculoskeletal System

Sarcoma ◽  
2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Barry Rose ◽  
George S. Tamvakopoulos ◽  
Eric Yeung ◽  
Robin Pollock ◽  
John Skinner ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Case Series ◽  
Immunohistochemical Analysis ◽  
Granular Cell ◽  
The Body ◽  
Soft Tissue Tumour ◽  
Granular Cell Tumour ◽  
Tissue Tumour ◽  
Neural Origin ◽  
Granular Cell Tumours

Granular Cell Tumours are rare mesenchymal soft tissue tumours that arise throughout the body and are believed to be of neural origin. They often present as asymptomatic, slow-growing, benign, solitary lesions but may be multifocal. 1-2% of cases are malignant and can metastasise. Described series in the literature are sparse. We identified eleven cases in ten patients treated surgically and followed-up for a period of over 6 years in our regional bone and soft tissue tumour centre. Five tumours were located in the lower limb, four in the upper limb, and two in the trunk. Mean patient age was 31.2 years (range 8–55 years). Excision was complete in one case, marginal in five cases and intralesional in five cases. No patients required postoperative adjuvant treatment. Mean follow-up was 19.3 months (range 1–37 months). One case was multifocal, but there were no cases of local recurrence or malignancy. Histopathological and immunohistochemical analysis revealed the classical granular cell tumour features in all cases. We believe this case series to be the largest of its type in patients presenting to an orthopaedic soft tissue tumour unit. We present our findings and correlate them with findings of other series in the literature.

Granular Cell Tumour of the Ulnar Nerve

1999 ◽  
Vol 24 (1) ◽  
pp. 122-124 ◽  
Author(s):  
T. YASUTOMI ◽  
H. KOIKE ◽  
Y. NAKATSUCHI
Keyword(s):  
Peripheral Nerve ◽  
Ulnar Nerve ◽  
Granular Cell ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Nerve Fibres ◽  
Neural Origin ◽  
Granular Cell Tumours

Although granular cell tumours have been demonstrated to have a neural origin, they rarely arise in peripheral nerve trunks. We report a case of granular cell tumour of the ulnar nerve in a 51-year-old man. Though dissectable from the nerve, this intraneural tumour showed microscopic involvement of focal nerve fibres. This tumour tended to infiltrate the nerve in the same manner as a neurofibroma.

Granular cell myoblastoma: Perineal neoplasm of probable neural origin

Urology ◽  
1977 ◽  
Vol 10 (2) ◽  
pp. 159-160 ◽  
Author(s):  
Anthony A. Eason ◽  
James Karol ◽  
Edward J. Collins
Keyword(s):  
Granular Cell ◽  
Granular Cell Myoblastoma ◽  
Neural Origin

A subset of so-called dermal non-neural granular cell tumours are underlined by ALK fusions, further supporting the idea that they represent a variant of epithelioid fibrous histiocytoma

2018 ◽  
Vol 73 (3) ◽  
pp. 532-534 ◽  
Author(s):  
Raul E Perret ◽  
Marie-Laure Jullie ◽  
Beatrice Vergier ◽  
Jean-Michel Coindre ◽  
François Le Loarer
Keyword(s):  
Fibrous Histiocytoma ◽  
Granular Cell ◽  
Granular Cell Tumours

Endocrine Tumors of the Appendix: A Pathologic Review

2010 ◽  
Vol 134 (6) ◽  
pp. 871-875
Author(s):  
Lydia Deschamps ◽  
Anne Couvelard
Keyword(s):  
Goblet Cell ◽  
Patient Management ◽  
Recent Literature ◽  
Surgical Intervention ◽  
Right Hemicolectomy ◽  
World Health ◽  
Endocrine Tumors ◽  
Management Guidelines ◽  
Pathologic Analysis ◽  
Health Organization

Abstract Context.—Although rare, appendiceal endocrine tumors are the most common neoplasms of the appendix. Pathologic analysis is important for guiding the management of patients. Objective.—To provide recent data that focus on the pathology of endocrine tumors of the appendix including classifications and guidelines for patient management. Data Sources.—A review of the recent literature including TNM classifications and patient management guidelines. Conclusions.—Appendiceal endocrine tumors are separated into 2 main groups: classic endocrine tumors and goblet cell carcinoids. They can be classified according to World Health Organization and TNM classifications. Evaluation of their prognoses and risks of malignancy, according to these classifications, depends on several parameters including tumor size, proliferation rate, and infiltration of appendiceal wall and mesoappendix. Most patients with classic endocrine tumors of the appendix have a favorable prognosis. Indications for postappendectomy, complementary surgery, which are still controversial, especially for tumors between 1 and 2 cm, are presented and discussed. In contrast, in patients presenting with a goblet cell carcinoid, a right hemicolectomy after the initial appendectomy is considered the standard surgical intervention.

PTU-155 Endoscopic Management of Granular Cell Tumours Arising in The Oesophagus: A Single Centre Experience

Gut ◽  
2016 ◽  
Vol 65 (Suppl 1) ◽  
pp. A133.2-A134
Author(s):  
N Jawad ◽  
F Norris ◽  
J Solomon ◽  
M Novelli ◽  
L Lovat ◽  
...  
Keyword(s):  
Granular Cell ◽  
Endoscopic Management ◽  
Single Centre ◽  
Single Centre Experience ◽  
Granular Cell Tumours

Granular cell tumour of the larynx in an eight-year-old girl

1993 ◽  
Vol 107 (10) ◽  
pp. 940-941 ◽  
Author(s):  
Abdalla M. Hamid ◽  
Abduljabbar Alshaikly
Keyword(s):  
Local Excision ◽  
Black People ◽  
Benign Neoplasm ◽  
Granular Cell ◽  
The Body ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Multiple Lesions ◽  
Granular Cell Tumours

AbstractGranular cell tumour is a rare benign neoplasm, that can affect many parts of the body, as single or multiple lesions. It is more common in black people and females. Typically it occurs between the fourth and fifth decades of life, with the median age for the laryngeal variety as 36 years. About 30 to 50 per cent occur in the tongue and 30 per cent in the skin.A case of granular cell tumour of the larynx is reported in an eight-year-old girl, presenting with hoarseness of voice. She was successfully treated with local excision of the tumour. This tumour is rare in the larynx where it is more common in males than females although granular cell tumours are found more frequently in females generally.For these reasons the authors suspect that their case, of a laryngeal granular cell tumour occurring in an eight-year-old girl might be the youngest to be reported.

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