Hypoxia During Anesthesia

2017 ◽  
Author(s):  
Natacha Zamor
Keyword(s):  
Oxygen Supply ◽  
Anesthesia Machine ◽  
Safety System ◽  
Pressure System ◽  
Oxygen Analyzer ◽  
Oxygen Nitrous Oxide ◽  
Low Pressure System ◽  
Hypoxic Gas Mixture ◽  
Distinct Role

In the modern anesthesia machine, there are various safety checks in place to help prevent the delivery of a hypoxic gas mixture to the patient. They include the pin index safety system (PISS), diameter index safety system (DISS), failsafe valve, oxygen-nitrous oxide proportioning system, oxygen supply failure alarm, flowmeter sequence, and, most distally, the oxygen analyzer. The PISS is a feature in the high-pressure system. The DISS, failsafe valve, and oxygen failure alarm are in the intermediate-pressure system. The flowmeters, proportioning system, and oxygen analyzer are in the low-pressure system. This chapter undertakes a discussion of the distinct role of each feature and their limitations.

A New Device to Check the Anesthesia Machine Low-pressure System

1993 ◽  
Vol 79 (3) ◽  
pp. 629-630 ◽  
Author(s):  
Alexander G. Targ ◽  
Bryan W. Andrews
Keyword(s):  
Anesthesia Machine ◽  
Low Pressure ◽  
Pressure System ◽  
New Device ◽  
Low Pressure System

scholarly journals Role of ocean mesoscale structures in shaping the Angola-Low pressure system and the southern Africa rainfall

2020 ◽  
Vol 54 (7-8) ◽  
pp. 3685-3704 ◽  
Author(s):  
Fabien Desbiolles ◽  
Emma Howard ◽  
Ross C. Blamey ◽  
Rondrotiana Barimalala ◽  
Neil C. G. Hart ◽  
...  
Keyword(s):  
Southern Africa ◽  
Low Pressure ◽  
Pressure System ◽  
Mesoscale Structures ◽  
Low Pressure System

scholarly journals Variations in intensity and structure of a westward-propagating monsoon depression

MAUSAM ◽  
2022 ◽  
Vol 44 (3) ◽  
pp. 231-238
Author(s):  
KSHUDIRAM SAHA ◽  
SURANJANA SAHA
Keyword(s):  
Bay Of Bengal ◽  
Arabian Sea ◽  
Heat Budget ◽  
Central India ◽  
Monsoon Depression ◽  
Pressure System ◽  
Thermal Fields ◽  
The North ◽  
Low Pressure System

The study deals with a monsoon depression which developed over the Bay of Bengal, moved westward across central India and turned into a mid-tropospheric disturbance (MTD) over the northeastern : corner of the Arabian Sea. Its interactions with the thermal fields associated with the basic monsoon, subtropical westerly troughs and a new depression over the Bay of Bengal are examined. Evidence suggests the involvement of all the three factors in causing the observed variations in its intensity and structure. The low pressure system turned into a mid-tropospheric disturbance when it re-entered the warm sector of the basic monsoon field and received increased warm advection from the north to the west of its centre and cold advection from the south to the east in mid-troposphere. The importance of thermal advection is confirmed by computation of a heat budget. The role of condensation heating is also briefly discussed.  

The role of afferents from the low-pressure system in the release of antidiuretic hormone during non-hypotensive hemorrhage

1968 ◽  
Vol 46 (2) ◽  
pp. 287-295 ◽  
Author(s):  
J. P. Henry ◽  
P. D. Gupta ◽  
J. P. Meehan ◽  
R. Sinclair ◽  
L. Share
Keyword(s):  
Blood Volume ◽  
Low Pressure ◽  
Systemic Circulation ◽  
Pressure System ◽  
Sharp Drop ◽  
Stretch Receptors ◽  
Femoral Vessels ◽  
Low Pressure System ◽  
Fluid Volume Regulation

Moderate hemorrhage insufficient to reduce seriously the pulse pressure, had no effect on the total flow of afferent impulses per unit time from stretch receptors of the high-pressure system (systemic circulation). However, it sharply reduced the flow from the atrial receptors of the low-pressure system (lesser circulation). Thus acute non-hypotensive blood volume loss permits a differentiation between the effects of the stretch receptors in the two divisions of the cardiovascular system. Eleven conscious animals were trained to lie quietly with catheters in the femoral vessels. The loss of no more than 10–20% of the estimated blood volume led to a sharp drop in atrial stretch receptor firing. Measurements of blood ADH showed variable increases which in most cases were to significant levels. Other aspects of cardiovascular and fluid volume regulation were affected by changes in firing of stretch receptors in the low-pressure system. They include the tachycardia of non-hypotensive hemorrhage and changes in kidney function with atrial distension.

THE ROLE OF BIOSIMULATION IN HUMAN CHEMICAL SAFETY SYSTEM

Human Ecology ◽  
2017 ◽  
pp. 46-52 ◽  
Author(s):  
L. M. Sosedova ◽  
T. M. Filippova
Keyword(s):  
Safety System ◽  
Chemical Safety

scholarly journals F4/80+ Kupffer Cell-Derived Oncostatin M Sustains the Progression Phase of Liver Regeneration through Inhibition of TGF-β2 Pathway

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2231
Author(s):  
Qingjun Lu ◽  
Hao Shen ◽  
Han Yu ◽  
Jing Fu ◽  
Hui Dong ◽  
...  
Keyword(s):  
Liver Regeneration ◽  
Serum Levels ◽  
Inhibitory Effect ◽  
Regenerative Process ◽  
Oncostatin M ◽  
Hepatocyte Proliferation ◽  
Initiation Phase ◽  
Distinct Role

The role of Kupffer cells (KCs) in liver regeneration is complicated and controversial. To investigate the distinct role of F4/80+ KCs at the different stages of the regeneration process, two-thirds partial hepatectomy (PHx) was performed in mice to induce physiological liver regeneration. In pre- or post-PHx, the clearance of KCs by intraperitoneal injection of the anti-F4/80 antibody (α-F4/80) was performed to study the distinct role of F4/80+ KCs during the regenerative process. In RNA sequencing of isolated F4/80+ KCs, the initiation phase was compared with the progression phase. Immunohistochemistry and immunofluorescence staining of Ki67, HNF-4α, CD-31, and F4/80 and Western blot of the TGF-β2 pathway were performed. Depletion of F4/80+ KCs in pre-PHx delayed the peak of hepatocyte proliferation from 48 h to 120 h, whereas depletion in post-PHx unexpectedly led to persistent inhibition of hepatocyte proliferation, indicating the distinct role of F4/80+ KCs in the initiation and progression phases of liver regeneration. F4/80+ KC depletion in post-PHx could significantly increase TGF-β2 serum levels, while TGF-βRI partially rescued the impaired proliferation of hepatocytes. Additionally, F4/80+ KC depletion in post-PHx significantly lowered the expression of oncostatin M (OSM), a key downstream mediator of interleukin-6, which is required for hepatocyte proliferation during liver regeneration. In vivo, recombinant OSM (r-OSM) treatment alleviated the inhibitory effect of α-F4/80 on the regenerative progression. Collectively, F4/80+ KCs release OSM to inhibit TGF-β2 activation, sustaining hepatocyte proliferation by releasing a proliferative brake.

scholarly journals Role of myoglobin in the oxygen supply to red skeletal muscle

1975 ◽  
Vol 250 (23) ◽  
pp. 9038-9043
Author(s):  
BA Wittenberg ◽  
JB Wittenberg ◽  
PR Caldwell
Keyword(s):  
Skeletal Muscle ◽  
Oxygen Supply

scholarly journals Distribution and function of carbamate hydrolase genes cehA and mcd in soils: the distinct role of soil pH

2018 ◽  
Vol 94 (6) ◽  
Author(s):  
Constantina Rousidou ◽  
Dionysis Karaiskos ◽  
Despoina Myti ◽  
Evangelos Karanasios ◽  
Panagiotis A Karas ◽  
...  
Keyword(s):  
Soil Ph ◽  
And Function ◽  
Distinct Role
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