Vascular Surgery

Blood vessels are formed from mesoderm-derived endothelial cells. Arteries, arterioles, and capillaries carry blood from the heart to tissues; venules and veins return blood to the heart. The force exerted by blood on the blood vessel wall is BP and is expressed in mm Hg. Vascular diseases present in various forms, such as bleeding, clotting, stroke, headache, and heart attack. Arteriography was the standard for evaluating arterial disease, but CT angiography and MRI are useful and ever improving. Postoperative concerns include bleeding, clotting, ischemia, stroke, and myocardial infarction.

Download Full-text

Construction of an artificial blood vessel wall from cultured endothelial cells

Developments in Cardiovascular Medicine - Biology of Endothelial Cells ◽

10.1007/978-1-4613-2825-4_5 ◽

1984 ◽

pp. 51-58

Author(s):

Robert F. Taylor

Keyword(s):

Endothelial Cells ◽

Blood Vessel ◽

Vessel Wall ◽

Blood Vessel Wall ◽

Artificial Blood ◽

Artificial Blood Vessel ◽

Cultured Endothelial Cells

Download Full-text

How leukocytes trigger opening and sealing of gaps in the endothelial barrier

F1000Research ◽

10.12688/f1000research.9185.1 ◽

2016 ◽

Vol 5 ◽

pp. 2321 ◽

Cited By ~ 6

Author(s):

Debashree Goswami ◽

Dietmar Vestweber

Keyword(s):

Endothelial Cells ◽

Blood Vessel ◽

Blood Vessels ◽

Immune Cells ◽

Molecular Basis ◽

Vessel Wall ◽

Endothelial Barrier ◽

Apical Surface ◽

Blood Vessel Wall ◽

Inner Surface

The entry of leukocytes into tissues requires well-coordinated interactions between the immune cells and endothelial cells which form the inner lining of blood vessels. The molecular basis for recognition, capture, and adhesion of leukocytes to the endothelial apical surface is well studied. This review will focus on recent advances in our understanding of events following the firm interaction of leukocytes with the inner surface of the blood vessel wall. We will discuss how leukocytes initiate the transmigration (diapedesis) process, trigger the opening of gaps in the endothelial barrier, and eventually move through this boundary.

Download Full-text

The Intravascular Generation of Fibrinogen Derivatives and the Blood Vessel Wall in Venous Thrombosis and Disseminated Intravascular Coagulation

Thrombosis and Haemostasis ◽

10.1055/s-0038-1651902 ◽

1977 ◽

Vol 38 (04) ◽

pp. 0831-0849 ◽

Cited By ~ 1

Author(s):

Gwendolyn J. Stewart

Keyword(s):

Blood Vessel ◽

Venous Thrombosis ◽

Vessel Wall ◽

Fluid Phase ◽

Primary Site ◽

Blood Vessel Wall ◽

Fibrin Deposition ◽

Tissue Destruction ◽

Fibrin Formation ◽

Rich Material

SummaryBoth deep venous thrombosis and DIC are intermediate mechanisms of disease – both are a consequence of the deposition of fibrin-rich material in blood vessels some distance from the primary site of tissue destruction. The great difference in the sites of fibrin deposition may depend on the extent and site of activation of the clotting mechanism. DIC likely occurs in the fluid phase of the blood as a consequence of massive fibrin formation while thrombosis results from limited fibrin formation at the interface between blood and vessel wall. Leukocytes may be essential for attaching thrombi to the vessel wall in many places.

Download Full-text