Pain Disorders

2020 ◽  
pp. 468-481
Author(s):  
Timothy Roehrs ◽  
Thomas Roth
Keyword(s):  
Chronic Pain ◽  
Daytime Sleepiness ◽  
Cognitive Factors ◽  
Insufficient Sleep ◽  
Behavioral Treatments

Information and appreciation regarding the role of insufficient sleep in chronic pain is now emerging. This chapter reviews the sleep, daytime sleepiness, and fatigue of people with various chronic pain disorders. The bidirectional relation of sleep and pain is described in this chapter, and the modulating effects of mood and cognitive factors on the sleep-pain nexus are discussed. Central and peripheral mechanisms underlying the sleep–pain nexus are explored. Finally, pharmacological and behavioral treatments for sleep and pain are reviewed with a focus on the association of improved sleep leading to improved pain. It is concluded that further research is necessary to better understand the interrelation of sleep and pain, which may lead to better therapies for sleep and pain.

Sleep disturbance in individuals with physical disabilities and chronic pain: The role of physical, emotional and cognitive factors

2019 ◽  
Vol 12 (4) ◽  
pp. 588-593 ◽  
Author(s):  
Rocío de la Vega ◽  
Jordi Miró ◽  
Rosa Esteve ◽  
Carmen Ramírez-Maestre ◽  
Alicia E. López-Martínez ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Sleep Disturbance ◽  
Physical Disabilities ◽  
Cognitive Factors

Prospective Memory Development Across the Lifespan

2020 ◽  
Vol 25 (3) ◽  
pp. 162-173 ◽  
Author(s):  
Sascha Zuber ◽  
Matthias Kliegel
Keyword(s):  
Prospective Memory ◽  
Healthy Aging ◽  
Present Model ◽  
Current Knowledge ◽  
Well Being ◽  
The Elderly ◽  
Cognitive Factors ◽  
Everyday Functioning ◽  
Integrative Framework

Abstract. Prospective Memory (PM; i.e., the ability to remember to perform planned tasks) represents a key proxy of healthy aging, as it relates to older adults’ everyday functioning, autonomy, and personal well-being. The current review illustrates how PM performance develops across the lifespan and how multiple cognitive and non-cognitive factors influence this trajectory. Further, a new, integrative framework is presented, detailing how those processes interplay in retrieving and executing delayed intentions. Specifically, while most previous models have focused on memory processes, the present model focuses on the role of executive functioning in PM and its development across the lifespan. Finally, a practical outlook is presented, suggesting how the current knowledge can be applied in geriatrics and geropsychology to promote healthy aging by maintaining prospective abilities in the elderly.

Role of Ethnicity on Pain Perception, Fatigue, and Quality of Life in a Pediatric Chronic Pain Population

2007 ◽  
Author(s):  
Jeffrey I. Gold ◽  
Trina Haselrig ◽  
D. Colette Nicolaou ◽  
Katharine A. Belmont
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Pain Perception ◽  
Pediatric Chronic Pain

Chemo- and Optogenetic Strategies for the Elucidation of Pain Pathways

2019 ◽  
pp. 816-832 ◽  
Author(s):  
Sascha R. A. Alles ◽  
Anne-Marie Malfait ◽  
Richard J. Miller
Keyword(s):  
Chronic Pain ◽  
Pain Response ◽  
Conscious Perception ◽  
Novel Therapies ◽  
The Past ◽  
Nociceptive Pathways ◽  
Pain Pathways ◽  
Technical Advances ◽  
The Brain

Pain is not a simple phenomenon and, beyond its conscious perception, involves circuitry that allows the brain to provide an affective context for nociception, which can influence mood and memory. In the past decade, neurobiological techniques have been developed that allow investigators to elucidate the importance of particular groups of neurons in different aspects of the pain response, something that may have important translational implications for the development of novel therapies. Chemo- and optogenetics represent two of the most important technical advances of recent times for gaining understanding of physiological circuitry underlying complex behaviors. The use of these techniques for teasing out the role of neurons and glia in nociceptive pathways is a rapidly growing area of research. The major findings of studies focused on understanding circuitry involved in different aspects of nociception and pain are highlighted in this article. In addition, attention is drawn to the possibility of modification of chemo- and optogenetic techniques for use as potential therapies for treatment of chronic pain disorders in human patients.

Differential role of adenosine signaling cascade in acute and chronic pain

2019 ◽  
Vol 712 ◽  
pp. 134483
Author(s):  
Morayo G. Adebiyi ◽  
Jeanne Manalo ◽  
Rodney E. Kellems ◽  
Yang Xia
Keyword(s):  
Chronic Pain ◽  
Signaling Cascade ◽  
Adenosine Signaling
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