scholarly journals Molecular Population Genetics of Redundant Floral-Regulatory Genes in Arabidopsis thaliana

2004 ◽  
Vol 22 (1) ◽  
pp. 91-103 ◽  
Author(s):  
Richard C. Moore ◽  
Sarah R. Grant ◽  
Michael D. Purugganan
2008 ◽  
Vol 8 (1) ◽  
pp. 111 ◽  
Author(s):  
Yen-Heng Lin ◽  
Shih-Ying Hwang ◽  
Po-Yen Hsu ◽  
Yu-Chung Chiang ◽  
Chun-Lin Huang ◽  
...  

Genetics ◽  
1999 ◽  
Vol 151 (2) ◽  
pp. 839-848 ◽  
Author(s):  
Michael D Purugganan ◽  
Jane I Suddith

Abstract Molecular variation in genes that regulate development provides insights into the evolutionary processes that shape the diversification of morphogenetic pathways. Intraspecific sequence variation at the APETALA3 and PISTILLATA floral homeotic genes of Arabidopsis thaliana was analyzed to infer the extent and nature of diversity at these regulatory loci. Comparison of AP3 and PI diversity with three previously studied genes revealed several features in the patterning of nucleotide polymorphisms common between Arabidopsis nuclear loci, including an excess of low-frequency nucleotide polymorphisms and significantly elevated levels of intraspecific replacement variation. This pattern suggests that A. thaliana has undergone recent, rapid population expansion and now exists in small, inbred subpopulations. The elevated intraspecific replacement levels may thus represent slightly deleterious polymorphisms that differentiate distinct ecotypes. The distribution of replacement and synonymous changes in AP3 and PI core and noncore functional domains also indicates differences in the patterns of molecular evolution between these interacting floral regulatory genes.


Author(s):  
Daniel L. Hartl

A Primer of Population Genetics and Genomics, 4th edition, has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics. Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention. This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.


2013 ◽  
Vol 14 (5) ◽  
pp. 316-323 ◽  
Author(s):  
Beatriz García ◽  
Alicia R. Pérez Rosas ◽  
María Blariza ◽  
Carla Grosso ◽  
Cintia Fernández ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document