Neurosarcoidosis Pathologically Diagnosed Via Biopsy of a Normal-Sized Inguinal Lymph Node With Fluorodeoxyglucose Accumulation on Positron Emission Tomography/Computed Tomography in a Patient With a History of Brain Ewing’s Sarcoma

Abstract Neurosarcoidosis is a rare disease and is often difficult to diagnose. Herein, we report a case of neurosarcoidosis in a patient with a history of Ewing’s sarcoma of the brain. He presented with fever of unknown origin, and a pathological diagnosis was obtained via biopsy of a normal-sized inguinal lymph node with fluorodeoxyglucose (FDG) accumulation on positron emission tomography/computed tomography (PET/CT). The condition could not have been diagnosed without FDG-PET/CT.

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Additive value of positron emission tomography/computed tomography scan for detection of aortic tube graft infection: a case report

European Heart Journal - Case Reports ◽

10.1093/ehjcr/ytaa512 ◽

2020 ◽

Author(s):

Farnoosh Larti ◽

Mohammad Amin Khadembashiri ◽

Mehrshad Abbasi ◽

Alborz Sherafati

Keyword(s):

Computed Tomography ◽

Positron Emission Tomography ◽

Diagnostic Accuracy ◽

Ct Scan ◽

Graft Infection ◽

Emission Tomography ◽

Positron Emission ◽

Pet Ct ◽

History Of ◽

Pet Ct Scan

Abstract Background Diagnosis of aortic graft infection is challenging, and delayed diagnosis is associated with poor prognosis. Positron emission tomography/computed tomography (PET/CT) has improved diagnostic accuracy. Case summary A patient with a history of congenital heart disease was admitted due to fever. He had a history of four cardiac surgeries, including the Bentall procedure for endocarditis. Blood cultures were negative. A semi-mobile mass was detected in the distal portion of the aortic tube graft in echocardiography. PET/CT scan was used to confirm tube graft infection and to support proceeding to cardiac surgery. Discussion Using multimodality imaging, including PET/CT scan in combination with echocardiography, can improve diagnostic accuracy for the detection of aortic tube graft infection, infection of prosthetic valves, or intra-cardiac devices, especially in high-risk surgical cases.

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Efficacy of Positron Emission Tomography in Diagnosis of Lateral Lymph Node Metastases in Patients with Rectal Cancer: A retrospective study

10.21203/rs.3.rs-119898/v1 ◽

2020 ◽

Author(s):

Ryohei Yukimoto ◽

Mamoru Uemura ◽

Takahiro Tsuboyama ◽

Tsuyoshi Hata ◽

Shiki Fujino ◽

...

Keyword(s):

Computed Tomography ◽

Positron Emission Tomography ◽

Rectal Cancer ◽

Lymph Node ◽

Cancer Patients ◽

Emission Tomography ◽

Short Axis ◽

Cutoff Value ◽

Positron Emission ◽

Pet Ct

Abstract Background The presence of lateral pelvic lymph node (LLN) metastasis is an essential prognostic factor in rectal cancer patients. Thus, preoperative diagnosis of LLN metastasis is clinically important to determine the therapeutic strategy. The aim of this study was to evaluate the efficacy of preoperative positron emission tomography/computed tomography (PET/CT) in the diagnosis of LLN metastasis. Methods Eighty-six patients with rectal cancer who underwent LLN dissection at Osaka University were included in this study. The maximum standardized uptake value (SUVmax) of the primary tumor and LLN were preoperatively calculated using PET/CT. Simultaneously, the short axis of the lymph node was measured using multi-detector row computed tomography (MDCT). The presence of metastases was evaluated by postoperative pathological examination. Results Of the 86 patients, LLN metastases developed in the left, right, and both LLN regions in 7, 8, and 2 patients, respectively. The diagnosis of the metastases was predicted with a sensitivity of 84%, specificity 94%, positive predictive value 62%, and negative predictive value 98% when the cutoff value of the LLN SUVmax was set at 1.5. The cutoff value of the short axis set at 7 mm on MDCT was most useful in diagnosing LLN metastases, but SUVmax was even more useful in terms of specificity.Conclusions The cutoff value of 1.5 for lymph node SUVmax in PET is a reasonable measure to predict the risk of preoperative LLN metastases in rectal cancer patients.

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The use of PET/CT in pregnancy: A case report of malignant parathyroid carcinoma and a review of the literature

Obstetric Medicine ◽

10.1177/1753495x17724950 ◽

2017 ◽

Vol 11 (1) ◽

pp. 45-49 ◽

Cited By ~ 3

Author(s):

Manpreet (Mona) Gill ◽

Winnie Sia ◽

Michael Hoskinson ◽

Erin Niven ◽

Rshmi Khurana

Keyword(s):

Computed Tomography ◽

Positron Emission Tomography ◽

Parathyroid Carcinoma ◽

Emission Tomography ◽

Positron Emission Tomography Scanning ◽

Healthy Baby ◽

Positron Emission ◽

Pet Ct ◽

History Of ◽

In Pregnancy

Positron emission tomography scanning is not commonly performed in pregnancy but can be done if required. Fetal doses of radiation can be minimized, and our case exemplifies the safe application of positron emission tomography/computed tomography in pregnancy. A 38-year-old woman in her first ongoing pregnancy presented at 28 weeks’ gestation with symptomatic hypercalcemia. Given a history of parathyroid carcinoma, recurrence was suspected. Ultrasound and magnetic resonance imaging failed to locate the lesion. However, positron emission tomography/computed tomography identified a culprit supraclavicular lymph node. This was excised under local anesthesia resulting in normalization of parathyroid hormone and calcium levels. A term, healthy baby was delivered. The literature provides support that the use of positron emission tomography/computed tomography is acceptable when indicated, and there are modifications to protocols that can further limit risk.

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Efficacy of positron emission tomography in diagnosis of lateral lymph node metastases in patients with rectal Cancer: a retrospective study

BMC Cancer ◽

10.1186/s12885-021-08278-6 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ryohei Yukimoto ◽

Mamoru Uemura ◽

Takahiro Tsuboyama ◽

Tsuyoshi Hata ◽

Shiki Fujino ◽

...

Keyword(s):

Computed Tomography ◽

Positron Emission Tomography ◽

Rectal Cancer ◽

Lymph Node ◽

Cancer Patients ◽

Emission Tomography ◽

Short Axis ◽

Cutoff Value ◽

Positron Emission ◽

Pet Ct

Abstract Background The presence of lateral pelvic lymph node (LLN) metastasis is an essential prognostic factor in rectal cancer patients. Thus, preoperative diagnosis of LLN metastasis is clinically important to determine the therapeutic strategy. The aim of this study was to evaluate the efficacy of preoperative positron emission tomography/computed tomography (PET/CT) in the diagnosis of LLN metastasis. Methods Eighty-four patients with rectal cancer who underwent LLN dissection at Osaka University were included in this study. The maximum standardized uptake value (SUVmax) of the primary tumor and LLN were preoperatively calculated using PET/CT. Simultaneously, the short axis of the lymph node was measured using multi-detector row computed tomography (MDCT). The presence of metastases was evaluated by postoperative pathological examination. Results Of the 84 patients, LLN metastases developed in the left, right, and both LLN regions in 6, 7, and 2 patients, respectively. The diagnosis of the metastases was predicted with a sensitivity of 82%, specificity of 93%, positive predictive value of 58%, negative predictive value of 98%, false positive value of 7%, and false negative value of 18% when the cutoff value of the LLN SUVmax was set at 1.5. The cutoff value of the short axis set at 7 mm on MDCT was most useful in diagnosing LLN metastases, but SUVmax was even more useful in terms of specificity. Conclusions The cutoff value of 1.5 for lymph node SUVmax in PET is a reasonable measure to predict the risk of preoperative LLN metastases in rectal cancer patients.

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