scholarly journals In vitro formation of cysts derived from a rat model of autosomal dominant polycystic kidney disease

1996 ◽  
Vol 11 (supp6) ◽  
pp. 58-61 ◽  
Author(s):  
R. Pey ◽  
M. Hafner ◽  
G. Schieren ◽  
J. Bach ◽  
N. Gretz
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Rat Model ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

scholarly journals An Overview of In Vivo and In Vitro Models for Autosomal Dominant Polycystic Kidney Disease: A Journey from 3D-Cysts to Mini-Pigs

2020 ◽  
Vol 21 (12) ◽  
pp. 4537
Author(s):  
Svenja Koslowski ◽  
Camille Latapy ◽  
Pierrïck Auvray ◽  
Marc Blondel ◽  
Laurent Meijer
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
In Vitro Models ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney ◽  
Stage Renal Disease ◽  
End Stage

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inheritable cause of end stage renal disease and, as of today, only a single moderately effective treatment is available for patients. Even though ADPKD research has made huge progress over the last decades, the precise disease mechanisms remain elusive. However, a wide variety of cellular and animal models have been developed to decipher the pathophysiological mechanisms and related pathways underlying the disease. As none of these models perfectly recapitulates the complexity of the human disease, the aim of this review is to give an overview of the main tools currently available to ADPKD researchers, as well as their main advantages and limitations.

Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model

2011 ◽  
Vol 15 (5) ◽  
pp. 676-687 ◽  
Author(s):  
Takafumi Toyohara ◽  
Takehiro Suzuki ◽  
Yasutoshi Akiyama ◽  
Daisuke Yoshihara ◽  
Yoichi Takeuchi ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Rat Model ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Metabolomic Profiling ◽  
Autosomal Dominant Polycystic Kidney

Quercetin inhibits renal cyst growth in vitro and via parenteral injection in a polycystic kidney disease mouse model

2018 ◽  
Vol 9 (1) ◽  
pp. 389-396 ◽  
Author(s):  
Yangyang Zhu ◽  
Tian Teng ◽  
Hu Wang ◽  
Hao Guo ◽  
Lei Du ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Mouse Model ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Renal Cyst ◽  
Monogenic Disease ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney ◽  
Cyst Growth

Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by massive enlargement of fluid-filled cysts in the kidney.

scholarly journals SP007OLIVE LEAF EXTRACT INHIBITS CELLULAR AND CYSTIC GROWTH IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: AN IN VITRO MODEL

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii104-iii104
Author(s):  
Giuseppina Toteda ◽  
Anna Perri ◽  
Donatella Vizza ◽  
Simona Lupinacci ◽  
Antonella La Russa ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Leaf Extract ◽  
In Vitro Model ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney ◽  
Vitro Model ◽  
Cystic Growth

Olive leaf extract counteracts cell proliferation and cyst growth in an in vitro model of autosomal dominant polycystic kidney disease

2018 ◽  
Vol 9 (11) ◽  
pp. 5925-5935
Author(s):  
G. Toteda ◽  
D. Vizza ◽  
S. Lupinacci ◽  
A. Perri ◽  
M. F. Scalise ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
In Vitro Model ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney ◽  
Vitro Model ◽  
Cyst Growth ◽  
Progressive Enlargement

–Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive enlargement of kidney cysts, leading to chronic kidney disease.

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