scholarly journals Athrombocytopenic thrombotic microangiopathy, a condition that could be overlooked based on current diagnostic criteria

2008 ◽  
Vol 24 (3) ◽  
pp. 1048-1050 ◽  
Author(s):  
S. A. De Serres ◽  
P. Isenring
2020 ◽  
Vol 112 (5) ◽  
pp. 697-706 ◽  
Author(s):  
Ken Sagou ◽  
Nobuaki Fukushima ◽  
Shun Ukai ◽  
Miyo Goto ◽  
Kazutaka Ozeki ◽  
...  

2019 ◽  
Vol 74 (6) ◽  
pp. 892-901 ◽  
Author(s):  
Naoko Sato ◽  
Takashi Tasaki ◽  
Hirotsugu Noguchi ◽  
Koji Irie ◽  
Toshiyuki Nakayama

2017 ◽  
Vol 158 (27) ◽  
pp. 1043-1050
Author(s):  
Orsolya Horváth ◽  
Zoltán Prohászka ◽  
Krisztián Kállay ◽  
Csaba Kassa ◽  
Anita Stréhn ◽  
...  

Abstract: Hematopoietic stem cell transplantation associated thrombotic microangiopathy is a multifactorial complication, and has variable incidence in study populations due to different diagnostic criteria. The diversity of activity parameters, like elevated laktát-dehidrogenáz, hematological parameters and kidney function are not specific variables after stem cell transplantation. Dysregulation of the classical and alternative pathway can play an important role in the pathomechanism of thrombotic microangiopathy, but the understanding of the role of complement activation under transplantation conditions requires further investigation. Monitoring of complement parameters, including terminal complement pathway activation complex during transplantation may help physicians to improve diagnostic strategy, to evaluate therapeutical options and to predict and follow up efficacy of complement blockade methods and supportive therapy. This review focuses on the development of diagnostic criteria and therapeutical options in thrombotic microangiopathy, and presents some preliminary findings while using different diagnostic criteria in pediatric patients. Orv Hetil. 2017; 158(27): 1043–1050.


Transfusion ◽  
2009 ◽  
Vol 49 (9) ◽  
pp. 1884-1889 ◽  
Author(s):  
Glen A. Kennedy ◽  
Shane Bleakley ◽  
Jason Butler ◽  
Kari Mudie ◽  
Natasha Kearey ◽  
...  

Author(s):  
Marcel Levi ◽  
Toshiaki Iba

AbstractOne of the significant complications of severe COVID-19 infections is a coagulopathy that seems to be related to the occurrence of venous and arterial thromboembolic disease. The coagulation changes mimic but are not identical to disseminated intravascular coagulation (DIC). The vast majority of patients with COVID-19 do not meet the criteria for usual forms of DIC. In addition, there seem to be features of a strong local pulmonary thrombotic microangiopathy and direct endothelial cell infection and injury by the virus that affect the coagulopathic response to severe COVID-19. It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria.


Author(s):  
W.T. Gunning ◽  
G.D. Haselhuhn ◽  
E.R. Phillips ◽  
S.H. Selman

Within the last few years, adrenal cortical tumors with features concordant with the diagnostic criteria attributed to oncocytomas have been reported. To date, only nine reported cases exist in the literature. This report is the tenth case presentation of a presumptively benign neoplasm of the adrenal gland with a rare differentiation. Oncocytomas are well recognized benign tumors of the thyroid, parathyroid, and salivary glands and of the kidney. Other organs also give rise to these types of tumors, however with less frequency than the former sites. The characteristics generally used to classify a tumor as an oncocytoma include the following criteria: the tumor is 1) usually a solitary circumscribed mass with no gross nor microscopic evidence of metastasis (no tissue nor vascular invasion), 2) fairly bland in terms of mitotic activity and nuclear morphology, and 3) composed of large eosinophillic cells in which the cytoplasm is packed full of mitochondria (Figure 1).


2020 ◽  
Vol 5 (1) ◽  
pp. 131-141
Author(s):  
Cristina Rincon ◽  
Kia Noelle Johnson ◽  
Courtney Byrd

Purpose The purpose of this study is to examine the frequency and type of speech disfluencies (stuttering-like and nonstuttering-like) in bilingual Spanish–English (SE) children who stutter (CWS) to SE children who do not stutter (CWNS) during narrative samples elicited in Spanish and English to provide further diagnostic information for this population and preliminary data toward an expansion of this study. Method Participants included six bilingual SE children (three CWS, three CWNS) ranging in age from 5 years to 7;5 (years;months) and recruited from the surrounding Houston, Texas area. Participants provided a narrative sample in English and Spanish. The frequency of speech disfluencies was tabulated, and mean length of utterance was measured for each sample. Results Results indicate that both talker groups exceed the diagnostic criteria typically used for developmental stuttering. Regardless of the language being spoken, CWS participants had a frequency of stuttering-like speech disfluencies that met or exceeded the diagnostic criteria for developmental stuttering that is based on monolingual English speakers. The CWNS participants varied in meeting the criteria depending on the language being spoken, with one of the three CWNS exceeding the criteria in both languages and one exceeding the criteria for percentage of stuttering-like speech disfluencies in one language. Conclusion Findings from this study contribute to the development of more appropriate diagnostic criteria for bilingual SE-speaking children to aid in the reduction of misdiagnoses of stuttering in this population.


2007 ◽  
Vol 177 (4S) ◽  
pp. 421-421
Author(s):  
Veronica Triaca ◽  
Christian O. Twiss ◽  
Ramdev Konijeti ◽  
Larissa V. Rodriguez ◽  
Shlomo Raz

1999 ◽  
Vol 1 ◽  
pp. S75-S75
Author(s):  
G HABIB ◽  
P BARNAY ◽  
J AVIERINOS ◽  
G DERUMEAUX ◽  
J LEFEVRE ◽  
...  

2006 ◽  
Vol 5 (12) ◽  
pp. 3
Author(s):  
PATRICE WENDLING
Keyword(s):  

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