scholarly journals MP099N-TERMINAL PROHORMONE OF BRAIN NATRIURETIC PEPTIDE BUT NOT C-TERMINAL PRE-PRO VASOPRESSIN (COPEPTIN) LEVEL IS ASSOCIATED WITH THE RESPONSE TO ANTIHYPERTENSIVE THERAPY IN HEMODIALYSIS PATIENTS

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii463-iii463
Author(s):  
Katarzyna Wyskida ◽  
Joanna Ficek ◽  
Rafał Ficek ◽  
Dagmara Adamska ◽  
Patrycja Jędrzejowska ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Antihypertensive Therapy ◽  
Hemodialysis Patients ◽  
Copeptin Level

scholarly journals N-Terminal Prohormone of Brain Natriuretic Peptide but not C-Terminal Pre-Pro Vasopressin (Copeptin) Level is Associated with the Response to Antihypertensive Therapy in Haemodialysis Patients

2017 ◽  
Vol 42 (6) ◽  
pp. 1013-1022 ◽  
Author(s):  
Katarzyna Wyskida ◽  
Joanna Ficek ◽  
Rafał Ficek ◽  
Dagmara Adamska ◽  
Patrycja Jędrzejowska ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Antihypertensive Therapy ◽  
Copeptin Level

scholarly journals N-terminal pro brain natriuretic peptide as a cardiac biomarker in Japanese hemodialysis patients

2018 ◽  
Vol 41 (3) ◽  
pp. 135-143 ◽  
Author(s):  
Minako Shimizu ◽  
Shigehiro Doi ◽  
Ayumu Nakashima ◽  
Takayuki Naito ◽  
Takao Masaki
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Odds Ratio ◽  
Ventricular Hypertrophy ◽  
Hemodialysis Patients ◽  
Left Ventricular ◽  
Ultrafiltration Rate ◽  
Natriuretic Peptide Level ◽  
Peptide Level

Purpose: This study examined the clinical significance of N-terminal pro brain natriuretic peptide level as a cardiac marker in Japanese hemodialysis patients. Methods: This was a multicenter cross-sectional study involving 1428 Japanese hemodialysis patients. Ultrasonic cardiography data at post-hemodialysis were obtained from 395 patients. We examined whether serum N-terminal pro brain natriuretic peptide levels were associated with cardiac parameters and assessed cut-off values and investigated factors associated with a reduced ratio of N-terminal pro brain natriuretic peptide levels pre- and post-hemodialysis. Results: Multivariate logistic regression analysis showed that pre- and post-hemodialysis N-terminal pro brain natriuretic peptide levels were associated with left ventricular hypertrophy on electrocardiogram (odds ratio: 3.10; p < 0.001 at pre-hemodialysis and odds ratio: 2.70; p < 0.001 at post-hemodialysis) and left ventricular hypertrophy on ultrasonic cardiography (odds ratio: 3.06; p < 0.001 at pre-hemodialysis and odds ratio: 3.15; p < 0.001 at post-hemodialysis). Post-N-terminal pro brain natriuretic peptide levels were also significantly associated with ejection fraction on urine chorionic gonadotrophin (ultrasonic cardiography; odds ratio: 35.83; p < 0.001). Receiver operating characteristic curves for predicting the presence of left ventricular hypertrophy on electrocardiogram and ultrasonic cardiography showed similar sensitivity (57.7%, 57.3% at pre-hemodialysis and 63.9%, 48.2% at post-hemodialysis) and specificity (66.5%, 72.9% at pre-hemodialysis and 59.2%, 81.9% at post-hemodialysis). Decreased ejection fraction on ultrasonic cardiography showed better sensitivity (78.6%) and specificity (88.7%). The N-terminal pro brain natriuretic peptide reduction ratio during a hemodialysis session correlated with Kt/V, membrane area, membrane type, modality, body weight gain ratio, treatment time, and ultrafiltration rate with multiple linear regression ( R: 0.53; p < 0.001 except for ultrafiltration rate ( p = 0.003)). Conclusion: Both pre- and post-hemodialysis N-terminal pro brain natriuretic peptide are associated with the presence of left ventricular hypertrophy in this population. The post-hemodialysis N-terminal pro brain natriuretic peptide level is a useful marker for systolic dysfunction.

Serum nitric oxide level correlates with serum brain natriuretic peptide and whole blood viscosity in hemodialysis patients

Nitric Oxide ◽  
2018 ◽  
Vol 77 ◽  
pp. 1-5
Author(s):  
Jong Hwan Jung ◽  
Dong Hwan Lee ◽  
Young I. Cho ◽  
Yoon Jung Chae ◽  
Yu Jin Jung ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Hemodialysis Patients ◽  
Whole Blood Viscosity ◽  
Nitric Oxide Level

Elevated Pro-Brain Natriuretic Peptide, Troponin T and Malnutrition Inflammatory Score in Chronic Hemodialysis Patients with Overt Cardiovascular Disease

2011 ◽  
Vol 117 (3) ◽  
pp. c198-c205 ◽  
Author(s):  
Hernán Trimarchi ◽  
Alexis Muryan ◽  
Vicente Campolo-Girard ◽  
Mariana Dicugno ◽  
Nanci Barucca ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Troponin T ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Inflammatory Score

Brain Natriuretic Peptide between Traditional and Nontraditional Risk Factors in Hemodialysis Patients: Analysis of Cardiovascular Mortality in a Two-Year Follow-Up

2011 ◽  
Vol 119 (2) ◽  
pp. c162-c170 ◽  
Author(s):  
G. Selim ◽  
O. Stojceva-Taneva ◽  
G. Spasovski ◽  
L. Georgievska-Ismail ◽  
B. Zafirovska-Ivanovska ◽  
...  
Keyword(s):  
Risk Factors ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Cardiovascular Mortality ◽  
Hemodialysis Patients

scholarly journals Association of N-Terminal Pro-brain Natriuretic Peptide With Volume Status and Cardiac Function in Hemodialysis Patients

2021 ◽  
Vol 8 ◽  
Author(s):  
Yaqiong Wang ◽  
Xuesen Cao ◽  
Jinbo Yu ◽  
Yongmei Zhang ◽  
Xianzhe Li ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Area Under The Curve ◽  
Volume Overload ◽  
Hemodialysis Patients ◽  
Receiver Operating Characteristic Curves ◽  
Confounding Variables ◽  
Structure Disorder ◽  
The Relationship ◽  
Hemodialysis Duration

Introduction: N-terminal-pro-brain natriuretic peptide (NT-pro BNP) is secreted by cardiomyocytes in cases of cardiac structure disorder and volume overload. However, the relationship between NT-pro BNP level and body fluid status in dialysis patients with reduced cardiac ejection function (EF) is uncertain. Therefore, we aimed to investigate this relationship.Methods: We enrolled patients who had been receiving hemodialysis for &gt;3 months. Blood sample, transthoracic echocardiographic, and bioimpedance spectroscopy measurements were performed during a midweek non-dialysis day. The predictive value of NT-pro BNP in hemodialysis patients with volume overload was analyzed.Results: A total of 129 hemodialysis patients (74 men and 55 women; mean age: 59.4 ± 13.0 years) were recruited. The average hemodialysis duration was 55.5 (23.9–93.4) months, the NT-pro BNP level was 4992 (2,033–15,807) pg/mL, and the value of overhydration was 2.68 ± 0.19 (−1.9 to 12.2) L. The NT-pro BNP level was independently correlated with overhydration in both the LVEF ≥ 60% (β = 0.236, P = 0.044) and LVEF &lt;60% (β = 0.516, P = 0.032) groups, even after adjustments for potentially confounding variables. In receiver operating characteristic curves of NT-pro BNP for predicting volume overload, the area under the curve was 0.783 [95% CI (0.688–0.879), P &lt; 0.001) and 0.788 [95% CI (0.586–0.989), P &lt; 0.001] in the LVEF ≥ 60% and LVEF &lt; 60% groups, respectively.Conclusions: NT-pro BNP is a predictive factor for volume overload in hemodialysis patients with or without EF declines.

scholarly journals The influence of visceral obesity on the N-terminal fragment of brain natriuretic peptide precursor (NT-proBNP) concentrations in hemodialysis patients

2012 ◽  
Vol 45 (6) ◽  
pp. 467-474
Author(s):  
Chikako Tsutaya ◽  
Megumi Tsushima ◽  
Yuriko Terayama ◽  
Kanemitsu Yamaya ◽  
Hisao Saitoh ◽  
...  
Keyword(s):  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Visceral Obesity ◽  
Hemodialysis Patients ◽  
Terminal Fragment ◽  
Peptide Precursor
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