Protein kinase C beta deficiency increases glucose-mediated peritoneal damage via M1 macrophage polarization and up-regulation of mesothelial protein kinase C alpha

Michael S Balzer; Alexandra Helmke; Martina Ackermann; Janis Casper; Lei Dong; Marcus Hiss; Yulia Kiyan; Song Rong; Kai Timrott; Sibylle von Vietinghoff; Le Wang; Hermann Haller; Nelli Shushakova

doi:10.1093/ndt/gfy282

Protein kinase C beta deficiency increases glucose-mediated peritoneal damage via M1 macrophage polarization and up-regulation of mesothelial protein kinase C alpha

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfy282 ◽

2018 ◽

Vol 34 (6) ◽

pp. 947-960 ◽

Cited By ~ 6

Author(s):

Michael S Balzer ◽

Alexandra Helmke ◽

Martina Ackermann ◽

Janis Casper ◽

Lei Dong ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Macrophage Polarization ◽

Kinase C ◽

M1 Macrophage ◽

Protein Kinase C Alpha ◽

Protein Kinase C Beta

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Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)80701-7 ◽

1993 ◽

Vol 268 (27) ◽

pp. 20110-20115

Author(s):

H Mischak ◽

J.H. Pierce ◽

J Goodnight ◽

M.G. Kazanietz ◽

P.M. Blumberg ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Phorbol Ester ◽

Myeloid Differentiation ◽

Kinase C ◽

Protein Kinase C Alpha ◽

Protein Kinase C Beta

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FP557DUAL INHIBITION OF CLASSICAL PROTEIN KINASE C-ALPHA AND PROTEIN KINASE C-BETA ISOFORMS REDUCES EPITHELIAL-TO-MESENCHYMAL TRANSITION OF MESOTHELIAL CELLS AND PREVENTS PERITONEAL DAMAGE IN A MOUSE MODEL OF CHRONIC PERITONEAL EXPOSE TO HIGH GLUCOSE DIALYSATE

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfv180.09 ◽

2015 ◽

Vol 30 (suppl_3) ◽

pp. iii260-iii260

Author(s):

Le Wang ◽

Michael Balzer ◽

Marcus Hiss ◽

Hermann Haller ◽

Nelli Shushakova

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Mouse Model ◽

High Glucose ◽

Epithelial To Mesenchymal Transition ◽

Mesothelial Cells ◽

Mesenchymal Transition ◽

Kinase C ◽

Protein Kinase C Alpha ◽

Protein Kinase C Beta

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Reconstitution of protein kinase C alpha function by the protein kinase C beta-I carboxy terminus

Molecular and Cellular Endocrinology ◽

10.1016/0303-7207(93)90230-h ◽

1993 ◽

Vol 98 (1) ◽

pp. 9-16 ◽

Cited By ~ 5

Author(s):

Amadeo M. Parissenti ◽

Su Lihe ◽

Heimo Riedel

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Carboxy Terminus ◽

Kinase C ◽

Protein Kinase C Alpha ◽

Alpha Function ◽

Protein Kinase C Beta

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Protein kinase C alpha and epsilon reduce Ca-sensitivity of force development in human myocardium by phosphorylation of troponin

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(08)60143-5 ◽

2008 ◽

Vol 7 ◽

pp. 50-50

Author(s):

J VANDERVELDEN ◽

V KOOIJ ◽

R ZAREMBA ◽

N BOONTJE ◽

G STIENEN

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Human Myocardium ◽

Force Development ◽

Kinase C ◽

Protein Kinase C Alpha ◽

Ca Sensitivity

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Association of two genetic markers within the protein kinase C beta gene with type 2 diabetes mellitus

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-2005-862960 ◽

2005 ◽

Vol 113 (S 1) ◽

Author(s):

MA Osterhoff ◽

M Herrmann ◽

M Lazdins ◽

S Kaiser ◽

R Assert ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Protein Kinase C ◽

Protein Kinase ◽

Genetic Markers ◽

Kinase C ◽

Beta Gene ◽

Protein Kinase C Beta

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Überexpression von Protein Kinase C beta im Skelettmuskel führt bei C57Bl/6 Mäusen zu Insulinresistenz

Diabetologie und Stoffwechsel ◽

10.1055/s-2006-943750 ◽

2006 ◽

Vol 1 (S 1) ◽

Author(s):

AM Hennige ◽

E Metzinger ◽

R Lammers ◽

MA Schneider ◽

R Lehmann ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kinase C ◽

Protein Kinase C Beta

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Untersuchung der Protein Kinase C beta II-Phosphorylierungszustände mittels zweidimensionalem Immunoblot

Aktuelle Ernährungsmedizin ◽

10.1055/s-2006-946781 ◽

2006 ◽

Vol 31 (03) ◽

Author(s):

S Richter ◽

M Osterhoff ◽

A Pfeiffer

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kinase C ◽

Protein Kinase C Beta

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Faculty Opinions recommendation of Phase I dose escalation and pharmacokinetic study of enzastaurin, an oral protein kinase C beta inhibitor, in patients with advanced cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1043078.492991 ◽

2006 ◽

Author(s):

Jeffrey Evans

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Phase I ◽

Advanced Cancer ◽

Pharmacokinetic Study ◽

Dose Escalation ◽

Kinase C ◽

Protein Kinase C Beta

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1,25-Dihydroxyvitamin D3 translocates protein kinase C beta to nucleus and enhances plasma membrane association of protein kinase C alpha in renal epithelial cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)41856-4 ◽

1994 ◽

Vol 269 (5) ◽

pp. 3257-3264 ◽

Cited By ~ 1

Author(s):

M. Simboli-Campbell ◽

A. Gagnon ◽

D.J. Franks ◽

J. Welsh

Keyword(s):

Plasma Membrane ◽

Protein Kinase C ◽

Protein Kinase ◽

Epithelial Cells ◽

Membrane Association ◽

Dihydroxyvitamin D3 ◽

Renal Epithelial Cells ◽

1,25 Dihydroxyvitamin D3 ◽

Kinase C ◽

Protein Kinase C Beta

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Differential regulation of phosphoinositide and phosphatidylcholine hydrolysis by protein kinase C-beta 1 overexpression. Effects on stimulation by alpha-thrombin, guanosine 5'-O-(thiotriphosphate), and calcium.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)50168-5 ◽

1992 ◽

Vol 267 (14) ◽

pp. 9826-9830

Author(s):

J.A. Pachter ◽

J.K. Pai ◽

R Mayer-Ezell ◽

J.M. Petrin ◽

E Dobek ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Differential Regulation ◽

Phosphatidylcholine Hydrolysis ◽

Kinase C ◽

Protein Kinase C Beta

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