scholarly journals 1379. Vaccination Rates among Liver Transplant Recipients at a Tertiary Care Hospital in Newark, NJ

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S775-S776
Author(s):  
Tilly Varughese ◽  
Michael Song ◽  
Joachim Sackey
Keyword(s):  
Hepatitis B ◽  
Liver Transplant ◽  
Hepatitis A ◽  
Hepatitis B Vaccination ◽  
Care Hospital ◽  
Transplant Recipients ◽  
Vaccination Rates ◽  
Increased Risk ◽  
Transplant Candidates ◽  
To Receive

Abstract Background Transplant candidates and recipients are at increased risk of infectious complications of vaccine-preventable diseases due to their longstanding immunosuppressive regimens. We assessed the rates of vaccination in our liver transplant patients at University Hospital (UH) in Newark, NJ. Methods Retrospective chart-review including patients > 18 years old who underwent liver transplantation at UH for a 3-year period from 01/01/2017 to 07/20/2020. Data collected included demographics, clinical outcomes, eligibility and receipt of vaccinations before and after transplantation, protection titers after administration of hepatitis vaccinations and presence of an ID outpatient consultation. We looked at the following receipt of vaccinations: Prevnar-13, Pneumovax-23, Influenza, TDaP, Shingrix, Varivax, Havrix and Engerix/Heplisav. Characteristics of study participants was analyzed using descriptive statistics and Chi-Square/Fisher’s Exact tests were used to test associations. Results 119 unique medical charts were reviewed and no patients were excluded. Of those patients who were eligible to receive Hepatitis A vaccination, only 44.8% were documented to receive vaccination and of those eligible to receive Hepatitis B vaccination, only 47.8% received it. Influenza vaccination pre-transplantation was 46% and 66.1% in post-transplant recipients. For the other vaccinations, during the pre-transplant period, 17.6 % of patients received Prevnar-13, 36.1% Pneumovax-23 and 20.2% TDaP and 26.1% received Shingrix. Patients who had ID consultation were significantly more likely to receive appropriate Hepatitis A and Hepatitis B vaccinations (p values 0.026 and 0.005). Conclusion We are not meeting national vaccination standards set by the American Society of Transplantation (AST) for optimal vaccination in this population. Our study can inform of possible solutions to increase vaccination rates in this population such as the simple addition of a smartphrase within EMR notes to remind providers to order appropriate vaccinations and eventually, a more long term solution of creation of a dedicated vaccination clinic and/or routine ID pre-transplant evaluations for all transplant candidates. Disclosures All Authors: No reported disclosures

scholarly journals Changes in the vaccination rate among healthcare workers in response to hospital policies

2018 ◽  
Vol 12 (04) ◽  
pp. 250-256
Author(s):  
Jin Young Lee ◽  
Ji Young Park ◽  
Young Hee Lee ◽  
Je Hun Kim ◽  
Jong Woo Park
Keyword(s):  
Hepatitis B ◽  
Influencing Factors ◽  
Financial Support ◽  
Healthcare Workers ◽  
Hepatitis A ◽  
Antibody Test ◽  
Hepatitis B Vaccination ◽  
Vaccination Rates ◽  
Immunization Rates ◽  
Vaccination Recommendation

Introduction: Vaccination is the most effective method of preventing infectious disease among healthcare workers (HCWs). Although HCWs are recommended to receive vaccination, the vaccination rates have been low. We sought to investigate the effect of HCWs’ vaccination recommendation program by the types of enforcement and influencing factors on compliance, with the aim of enhancing their immunity. Methodology: First and second interventions were carried out. During the first intervention, vaccinations were recommended through official documents. Hepatitis B vaccination was mandatory. Diphtheria toxoid, acellular pertussis (Tdap) and Hepatitis A vaccinations were recommended without financial support. MMR and varicella vaccinations were recommended with fees for the antibody test were covered by the hospital. One-to-one consultation (OC) regarding vaccination was held in the second intervention. Aside from the OC, the second intervention followed the same procedure as the first intervention for the antibody tests and vaccination, but differed in that pertussis vaccination fees were covered. Results: The immunization rates for infectious diseases were greater after the second intervention than the first intervention. The rate of immunized HCWs with hepatitis B virus was 100% at the end of the second intervention. The greatest increase in immunization rates from the first to the second intervention was that for pertussis, and the second greatest was that for hepatitis A. Age and working units were influencing factors on hepatitis A vaccine compliance. Conclusions: In order to increase vaccination rates, efforts must be made to deliver information to individual HCWs through OC as well as financial support including a mandatory policy.

scholarly journals Hepatitis A and Hepatitis B Vaccination Coverage Among Persons Who Inject Drugs and Have Evidence of Hepatitis C Infection

2019 ◽  
Vol 134 (6) ◽  
pp. 651-659 ◽  
Author(s):  
Ruth Koepke ◽  
Danielle N. Sill ◽  
Wajiha Z. Akhtar ◽  
Kailynn P. Mitchell ◽  
Sheila M. Guilfoyle ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hepatitis B ◽  
Vaccination Coverage ◽  
Hepatitis A ◽  
Vaccine Coverage ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Vaccination ◽  
Persons Who Inject Drugs ◽  
Immunization Registry ◽  
Increased Risk

Objectives: Despite recommendations for vaccination against hepatitis A virus (HAV) and hepatitis B virus (HBV) for all adults at increased risk of infection, several US states have reported increases in HAV and HBV infections among persons who inject drugs. We investigated hepatitis A and hepatitis B vaccination coverage among a sample of persons who reported injecting drugs and had evidence of hepatitis C virus (HCV) infection. Methods: We searched the Wisconsin Immunization Registry for the vaccination records of persons who underwent HCV testing at syringe services programs from January 1 through August 31, 2018, and were reported to the Wisconsin Division of Public Health as having positive HCV antibody test results and a history of injection drug use. We calculated the percentage of persons who were vaccinated according to national recommendations. Results: Of 215 persons reported, 204 (94.9%) had a client record in the Wisconsin Immunization Registry. Of these 204 persons, 66 (32.4%) had received ≥1 dose of hepatitis A vaccine, 46 (22.5%) had received 2 doses of hepatitis A vaccine, and 115 (56.4%) had received 3 doses of hepatitis B vaccine. Hepatitis B vaccine coverage decreased with increasing age, from 88.0% (22 of 25) among adults aged 20-24 to 30.3% (10 of 33) among adults aged 35-39. Conclusions: These findings suggest that most persons who inject drugs in Wisconsin are susceptible to HAV infection and that most persons aged ≥35 who inject drugs are susceptible to HBV infection. In addition to routine vaccination of children, targeted hepatitis vaccination programs should focus on adults who inject drugs to help prevent future infections.

Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness

2009 ◽  
Vol 22 (8) ◽  
pp. 805-813 ◽  
Author(s):  
Hiroyuki Tahara ◽  
Yuka Tanaka ◽  
Kohei Ishiyama ◽  
Kentaro Ide ◽  
Masayuki Shishida ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Liver Transplant ◽  
Hepatitis B Vaccination ◽  
Transplant Recipients ◽  
Liver Transplant Recipients

scholarly journals 1754. Pre-Transplant Vaccination Rates in Solid-Organ Transplant Recipients

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S643-S644
Author(s):  
Daniel Friedman ◽  
Sara Belga ◽  
Catherine Burton ◽  
Jutta Preiksaitis ◽  
Dima Kabbani
Keyword(s):  
Hepatitis B ◽  
Liver Transplant ◽  
Kidney Transplant ◽  
Pneumococcal Vaccine ◽  
Hepatitis A ◽  
Solid Organ ◽  
Transplant Recipients ◽  
International Guidelines ◽  
Adult Kidney ◽  
Liver Transplant Recipients

Abstract Background Recipients of solid-organ transplants (SOT) are at increased risk of vaccine-preventable illnesses. Because of the immunosuppression administered following SOT, live vaccines are generally contraindicated post-SOT, and response to inactivated vaccines may be suboptimal. National and international guidelines recommend optimizing immunizations prior to SOT. We analyzed rates of vaccination for SOT candidates in a cohort of adult kidney and liver transplant recipients. Methods A retrospective chart review of adult kidney, kidney/pancreas (KP) and liver transplant recipients was conducted between 2014 and 2016. We calculated the rates of vaccinations of the following vaccines: pneumococcus, meningococcus, Hepatitis A and B, Haemophilus influenzae type B, measles, mumps, rubella, polio, tetanus, diphtheria and pertussis. Results 300 patients were included (147 kidney, 14 KP, 139 liver). Liver recipients were older (mean age 53 vs. 50; P = 0.028) and less likely to have had a previous transplant (5.8% vs. 21.1%; P < 0.001) or a living donor (15.8% vs. 32.3%, P = 0.01). Liver recipients were more likely to have been vaccinated against hepatitis A (106 [53.9%] vs. 28 [17.4%]; P < 0.001). Kidney and KP recipients were more likely to have received at least 1 dose of hepatitis B vaccine (138 [85.7%] vs. 91 [65.5%]; P < 0.001) or at least 1 dose of any of the pneumococcal vaccines (PSV23 94 [67.6%] vs. 92 [57.1%]; P = 0.062; PCV13 130 [80.7%] vs. 93 [66.9%]; P = 0.006; pneumococcal vaccine not clarified 47 [29.2%] vs. 14 [10.1%]; P < 0.001). No difference was observed with regards to other vaccines (Table 1). Being a kidney transplant recipient increased the odds of getting at least 1 dose of hepatitis B, tetanus/diphtheria/acellular pertussis (Tdap), measles, and pneumococcal vaccine (OR = 1.75, 95% CI [1.063–2.864]; P = 0.028) Conclusion In our cohort, kidney transplant recipients were more likely to have received pre-transplant vaccination. Despite the availability of local and international guidelines, vaccination in SOT candidates remains suboptimal and further study of barriers to implementation of these guidelines is warranted to inform future quality improvement initiatives. Disclosures All authors: No reported disclosures.

Accelerated Schedule of Hepatitis B Vaccination in Liver Transplant Candidates

1998 ◽  
Vol 30 (3) ◽  
pp. 797-799 ◽  
Author(s):  
B Kallinowski ◽  
C Benz ◽  
L Buchholz ◽  
W Stremmel
Keyword(s):  
Hepatitis B ◽  
Liver Transplant ◽  
Hepatitis B Vaccination ◽  
Transplant Candidates
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