scholarly journals The Association between Foot Surgery Type and Subsequent Healing in Veterans with Moderate-to-Severe Diabetic Foot Infections

2021 ◽  
Author(s):  
Justin J Kim ◽  
Alyson J Littman ◽  
John D Sorkin ◽  
Mary-Claire Roghmann
Keyword(s):  
Diabetic Foot ◽  
Common Knowledge ◽  
Foot Surgery ◽  
Bone Resection ◽  
Diabetic Foot Infections ◽  
Common Precursor ◽  
Confounding Variables ◽  
Binomial Regression ◽  
Transmetatarsal Amputation

Abstract Background Diabetic foot infections are a common precursor to lower extremity amputations. The treatment of diabetic foot infections involves both medical and surgical management, of which limb-sparing surgeries are increasingly preferred over amputations at or above the ankle to preserve mobility and quality of life. The outcomes following these limb-sparing surgeries are not well-described. Methods This was a single-center, retrospective cohort study of 90 Veterans with moderate-to-severe diabetic foot infections between 2017 and 2019 from the VA Maryland Health Care System. The exposure was foot surgery with bone resection (i.e., toe amputation, metatarsal resection, transmetatarsal amputation) versus debridement alone. The outcome was healing within 1 year. We used log-binomial regression to assess the association between foot surgery type and healing, stratify by infection location, and evaluate potential confounding variables. Results The cumulative incidence of healing after foot surgery with bone resection was greater than that following debridement (risk ratio 1.80, 95% confidence interval [1.17, 2.77]). This association was modified by infection location and greater for toe infections (4.52 [1.30, 15.7]) than other foot infections (1.19 [0.69, 2.02]). We found no evidence of confounding by comorbidities or infection severity. Conclusions For patients with toe infections, foot surgery with bone resection was associated with better healing than debridement alone. The multiple specialties caring for patients with diabetic foot infections need a stronger common knowledge base—from studies like this and future studies—to better counsel patients about their treatment and prognosis.

scholarly journals Manuscript title: The microbiology of diabetic foot infections: a single-center retrospective study and literature review

2021 ◽  
Vol 97 (1) ◽  
pp. 11-20
Author(s):  
Márió Gajdács ◽  
◽  
Gabriella Terhes ◽  
Marianna Ábrók ◽  
Andrea Lázár ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Late Onset ◽  
Infectious Complications ◽  
Limb Amputation ◽  
Diabetic Patients ◽  
Diabetic Foot Infections ◽  
Treatment Of Infection ◽  
Careful Management ◽  
Microbiological Procedures

Late-onset complications may cause serious problems in diabetic patients. Among these complications, diabetic foot infections play a signifcant role. In the recognition and management of the disease the microbiological procedures are essential. Neglected infectious complications may lead to gangrene, limb amputation, which not only impairs quality of life but also endangers the patient’s life. Prevention should include careful management of metabolic disease, appropriate medication, early detection of neuropathy, and the detection and treatment of infection by a medical team , including clinical microbiologist. In our present study, we retrospectively assessed the bacteriological culture’ results of patients with “diabetic foot” syndrome in 5-years’ clinical material at he Faculty of Medicine, University of Szeged.

Self-Reported Quality of Life and Diabetic Foot Infections

2014 ◽  
Vol 53 (6) ◽  
pp. 716-719 ◽  
Author(s):  
Katherine M. Raspovic ◽  
Dane K. Wukich
Keyword(s):  
Quality Of Life ◽  
Diabetic Foot ◽  
Diabetic Foot Infections

scholarly journals Non-surgical therapy of diabetic foot infections based on recent guidelines and published data

2020 ◽  
Vol 93 (2) ◽  
pp. 53-62
Author(s):  
Urbán Edit ◽  
Gajdács Márió
Keyword(s):  
Surgical Therapy ◽  
Diabetic Foot ◽  
Eating Habits ◽  
Published Data ◽  
Diabetic Foot Infections ◽  
Increasing Trend ◽  
Onset Of Diabetes ◽  
Diabetic Foot Osteomyelitis

Abstract Chronic, non-communicable diseases are affecting the lives of more and more people worldwide; due to obesity and inadequate eating habits, the proportion of diabetics is on an increasing trend globally. The development of a number of macro- and microangiopathic pathologies associated with the onset of diabetes affects the life expectancy of patients. Diabetic foot infection (DFI) is one of the most serious long-term complications of diabetes and may be considered an intersection of infectious and non-infectious diseases; these infections can significantly reduce the quality of life of affected patients. The purpose of this review was to summarize the latest recommendations for conservative (non-surgical) therapy for DFIs and diabetic foot osteomyelitis (DFO).

Extending Limb Salvage After Fourth and Fifth Transmetatarsal Amputation in Diabetic Foot Infections Using ACell® Urinary Bladder Matrix

2020 ◽  
pp. 000313482097373
Author(s):  
Phoenix Underwood ◽  
Paul Cardinal ◽  
Elena Keller ◽  
Robert Goodfellow ◽  
Thomas Scalea ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Limb Salvage ◽  
Diabetic Foot ◽  
Urinary Bladder Matrix ◽  
Diabetic Foot Infections ◽  
Transmetatarsal Amputation

The fate of formaldehyde in sugar manufacture and in products

2015 ◽  
pp. 692-696
Author(s):  
Remi Aubry ◽  
Laurence Gasnot
Keyword(s):  
Sugar Industry ◽  
Common Knowledge ◽  
Microbial Populations ◽  
Optimal Dosage ◽  
Consumer Health ◽  
Microbiological Activity ◽  
Specific Process ◽  
Beet Sugar ◽  
Series Of Experiments

A study was carried out in six beet sugar factories in France during the 2012/13 sugar campaign. The objective was to assess the optimal dosage of formaldehyde solutions at specific process stages and in different existing factory set-ups in order to obtain the desired effect on microbial populations, without interference with the quality of the products. In addition harmlessness regarding consumer health was to be demonstrated. A series of experiments was conducted resulting in new data allowing refreshment of common knowledge and references existing regarding the use of formaldehyde solutions in the sugar industry. The effectiveness and convenience for controlling microbiological activity in beet sugar manufacture was assessed. Formaldehyde reduces sugar losses and protects in-process products without harming their further use, such as for ethanol production.

scholarly journals Response Behavior and Quality of Survey Data: Comparing Elderly Respondents in Institutions and Private Households

2021 ◽  
pp. 004912412199553
Author(s):  
Jan-Lucas Schanze
Keyword(s):  
Data Quality ◽  
The Elderly ◽  
Response Behavior ◽  
Quality Of Data ◽  
Social Surveys ◽  
Private Households ◽  
Confounding Variables ◽  
Health Related ◽  
Survey Interviews

An increasing age of respondents and cognitive impairment are usual suspects for increasing difficulties in survey interviews and a decreasing data quality. This is why survey researchers tend to label residents in retirement and nursing homes as hard-to-interview and exclude them from most social surveys. In this article, I examine to what extent this label is justified and whether quality of data collected among residents in institutions for the elderly really differs from data collected within private households. For this purpose, I analyze the response behavior and quality indicators in three waves of Survey of Health, Ageing and Retirement in Europe. To control for confounding variables, I use propensity score matching to identify respondents in private households who share similar characteristics with institutionalized residents. My results confirm that most indicators of response behavior and data quality are worse in institutions compared to private households. However, when controlling for sociodemographic and health-related variables, differences get very small. These results suggest the importance of health for the data quality irrespective of the housing situation.

scholarly journals Spectral and Antibiotic Susceptibility of Pathogens Isolated from Saudi Patients with Diabetic Foot Infections

2021 ◽  
Vol 12 (1) ◽  
pp. 16-20
Author(s):  
Samiah Hamad S Al-Mijalli
Keyword(s):  
Staphylococcus Aureus ◽  
Diabetic Foot ◽  
Antibiotic Susceptibility ◽  
Empirical Therapy ◽  
Multidrug Resistant ◽  
Foot Ulcers ◽  
Sensitivity Testing ◽  
Cross Sectional ◽  
Diabetic Foot Infections ◽  
Microbiological Methods

Diabetic foot infections (DFIs) are a significant health issue and a common complication among patients with diabetes. To develop antibiotic therapy for these high-risk patients, the current study evaluates the scope of DFIs and identifies the causing microbes. It also measures spectrum and antibiotic susceptibility of the pathogens isolated from adults with DFIs in Saudi Arabia. To achieve the study objectives, a cross-sectional study was implemented and the baseline characteristics for 44 patients with DFIs were defined. Optimal aerobic and anaerobic microbiological techniques were utilized to culture specimens isolated from infected foot ulcers. The standard microbiological methods were employed to identify the bacterial isolates and antibiotic susceptibility testing was conducted following the procedures of the Clinical and Laboratory Standards Institute (CLSI). Results showed that 12 microorganisms were isolated from the participants’ diabetic foot ulcers. Staphylococcus Aureus was ranked first because it appeared in 29 (65.9%) cases. Streptococcus Agalactiae was ranked second and multi-microbial infections were also found. Most of the organisms were susceptible to Vancomycin, Ciprofloxacin, and Cefalexin, but they were resistant to Methicillin, Gentamicin, and Ampicillin antibiotics. Staphylococcus Aureus was most sensitive to Ciprofloxacin, while it was resistant to Methicillin. About 10% of the isolates were multidrug-resistant. The study concludes that while Vancomycin should be used empirically for Gram-positive isolates, Ciprofloxacin can be taken into consideration for most of the Gram-negatives aerobes. Based on including various microorganisms and the advent of multidrug-resistant strains, proper culture and sensitivity testing are necessary prior to the empirical therapy.

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