scholarly journals Infection of a prosthetic knee joint with Clostridium bifermentans

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Lisa F Barrett ◽  
Sailaja Devi Saragadam ◽  
Christina N DiMaria ◽  
Alejandro Delgado-Daza

ABSTRACT We present the first reported case of prosthetic joint infection caused by Clostridium bifermentans, which was treated with total joint washout and debridement allowing for the patient to retain his prosthesis and achieve full recovery. Clostridium bifermentans is a gram-positive, anaerobic, spore-forming bacterium. This organism was once considered to be non-pathogenic, but has recently been associated with cases of septic arthritis, empyema, osteomyelitis, soft tissue infection, brain abscess, bacteremia and endocarditis.

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Masahide Fujiki ◽  
Shimpei Miyamoto ◽  
Fumihiko Nakatani ◽  
Akira Kawai ◽  
Minoru Sakuraba

Rotationplasty is used most often as a function-preserving salvage procedure after resection of sarcomas of the lower extremity; however, it is also used after infection of prosthetic knee joints. Conventional vascular management during rotationplasty is to preserve and coil major vessels, but recently, transection and reanastomosis of the major vessels has been widely performed. However, there has been little discussion regarding the optimal vascular management of rotationplasty after infection of prosthetic knee joints because rotationplasty is rarely performed for this indication. We reviewed four patients who had undergone resection of osteosarcomas of the femur, placement of a prosthetic knee joint, and rotationplasty with vascular reconstruction from 2010 to 2013. The mean interval between prosthetic joint replacement and rotationplasty was 10.4 years and the mean interval between the diagnosis of prosthesis infection and rotationplasty was 7.9 years. Rotationplasty was successful in all patients; however, in one patient, arterial thrombosis developed and necessitated urgent surgical removal and arterial reconstruction. All patients were able to walk independently with a prosthetic limb after rehabilitation. Although there is no consensus regarding the most appropriate method of vascular management during rotationplasty for revision of infected prosthetic joints, vascular transection and reanastomosis is a useful option.


2017 ◽  
Vol 55 (2) ◽  
pp. 192-200 ◽  
Author(s):  
B. S. Belov ◽  
S. A. Makarov ◽  
E. I. Byalik

1995 ◽  
Vol 14 (7) ◽  
pp. 599-601 ◽  
Author(s):  
B. Pron ◽  
J. Merckx ◽  
P. Touzet ◽  
A. Ferroni ◽  
C. Poyart ◽  
...  

Orthopedics ◽  
2013 ◽  
Vol 36 (11) ◽  
pp. e1464-e1469 ◽  
Author(s):  
Steven F. Harwin ◽  
Samik Banerjee ◽  
Kimona Issa ◽  
Bhaveen H. Kapadia ◽  
Robert Pivec ◽  
...  

2000 ◽  
Vol 11 (6) ◽  
pp. 329-331 ◽  
Author(s):  
Jihad Bishara ◽  
Eyal Robenshtok ◽  
Zmira Samra ◽  
Silvio Pitlik

Prosthetic joint infection is usually caused byStaphylococcus aureus, coagulase-negative staphylococci and, less commonly, by Gram-negative bacilli and anaerobes. A case of prosthetic joint infection due toPseudomonas stutzeriin a 73-year-old female with acute promyelocytic leukemia is presented, and the pertinent literature is reviewed. Although the patient had prolonged neutropenia, the infection was successfully treated with antibiotics and without artificial joint replacement.


2016 ◽  
Vol 24 (10) ◽  
pp. 3050-3055 ◽  
Author(s):  
Sufian S. Ahmad ◽  
Roland Becker ◽  
Antonia F. Chen ◽  
Sandro Kohl

2016 ◽  
Vol 18 (12) ◽  
pp. 110-116 ◽  
Author(s):  
B.S. Belov ◽  
◽  
S.A. Makarov ◽  
E.I. Bialik ◽  
◽  
...  

Infection ◽  
2019 ◽  
Vol 47 (6) ◽  
pp. 1013-1020 ◽  
Author(s):  
Selma Tobudic ◽  
Christina Forstner ◽  
Heinz Burgmann ◽  
Heimo Lagler ◽  
Christoph Steininger ◽  
...  

Abstract Purpose Dalbavancin is a novel lipoglycopeptide with potent activity against several gram-positive pathogens, an excellent safety profile and a long elimination half-life. Methods In this case series observed at the University Hospital of Vienna between 2015 and 2017, all adult patients with gram-positive infections who received at least one dosage of dalbavancin were screened (n = 118). A total of 72 patients were included in the final analysis. The number of included patients stratified by the source of infection was: skin and soft tissue infection (SSTI) (n = 26), osteomyelitis (n = 20), spondylodiscitis (n = 14), acute septic arthritis (n = 4) and prosthetic joint infection (n = 8). Results In 46 patients (64%), clinical cure was detected at the end of dalbavancin therapy without additional antibiotic therapy. Of the 26 patients who received additional antibiotic therapy other than dalbavancin, 15 patients (21%) showed no clinical improvement under dalbavancin therapy, four patients (5%) had side effects (nausea n = 1, exanthema n = 2, hyperglycemia n = 1), and in seven patients (10%) clinical improvement under dalbavancin therapy was detected but antibiotic therapy was de-escalated to an oral drug. Conclusion We demonstrated high clinical effectiveness of dalbavancin for acute gram-positive infections primarily acute SSTI, acute septic arthritis, acute osteomyelitis and spondylodiscitis. In patients with biofilm-associated infection (chronic infection or joint prosthesis), source control was absolutely necessary for treatment success.


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