scholarly journals Severe dyslipidemia associated with diabetic ketoacidosis in newly diagnosed female of type 1 diabetes mellitus

2021 ◽  
Vol 2021 (10) ◽  
Author(s):  
Ahmad Chreitah ◽  
Kheria Hijazia ◽  
Leen Doya ◽  
Alaa Salloum
Keyword(s):  
Diabetes Mellitus ◽  
Acute Pancreatitis ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Rare Event ◽  
Newly Diagnosed ◽  
Severe Hypertriglyceridemia

ABSTRACT Diabetic ketoacidosis (DKA) is considered as a serious complication of type 1 diabetes mellitus in pediatrics. Severe dyslipidemia in DKA is a rare eventuality. We report on a 10-year-old female presented with severe DKA. The serum was lipemic with severe hypertriglyceridemia and hypercholesterolemia. Laboratory workup: the values of glycemia, sodium and HbA1c were misleading; a method of dilution was used to obtain the correct values. Triglyceride and cholesterol returned gradually to normal levels only with the management of DKA without any complication. Mild dyslipidemia is a common feature in DKA, but severe dyslipidemia is a very rare event whose pathophysiology is not completely elucidated. It needs close surveillance because it might be responsible for acute pancreatitis and lipidemia retinalis.

scholarly journals Hypertriglyceridemia-induced acute pancreatitis with diabetic ketoacidosis: A rare presentation of type 1 diabetes mellitus

2017 ◽  
Vol 9 (04) ◽  
pp. 329-331 ◽  
Author(s):  
Prabhat Kumar ◽  
Abhishek Sakwariya ◽  
Amit Ranjan Sultania ◽  
Renu Dabas
Keyword(s):  
Diabetes Mellitus ◽  
Acute Pancreatitis ◽  
Type 1 Diabetes ◽  
Diabetic Ketoacidosis ◽  
Insulin Infusion ◽  
Rare Presentation ◽  
Chronic Hyperglycemia ◽  
Severe Hypertriglyceridemia ◽  
Peptide Level

AbstractDiabetic ketoacidosis (DKA) is a frequently encountered complication of diabetes mellitus. DKA is an insulin deficit state and results in moderate to severe hypertriglyceridemia (HTG). HTG is the third leading cause of acute pancreatitis (AP) and often goes unnoticed. The triad of DKA, HTG, and AP is rarely seen, and literature on the same is sparse. We report a case of AP which was due to DKA-induced secondary HTG in an adult with previously undiagnosed type 1 diabetes. His HbA1c was significantly raised, and C-peptide level was low, confirming chronic hyperglycemia. He was treated successfully with insulin infusion, intravenous crystalloid, and analgesics.

Increased incidence and severity of diabetic ketoacidosis among uninsured children with newly diagnosed type 1 diabetes mellitus

2005 ◽  
Vol 6 (2) ◽  
pp. 79-83 ◽  
Author(s):  
Aristides K. Maniatis ◽  
Stephanie H. Goehrig ◽  
Dexiang Gao ◽  
Arleta Rewers ◽  
Philippe Walravens ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Newly Diagnosed ◽  
Uninsured Children

A brief campaign to prevent diabetic ketoacidosis in children newly diagnosed with type 1 diabetes mellitus: The NO-DKA Study

2018 ◽  
Vol 19 (7) ◽  
pp. 1257-1262 ◽  
Author(s):  
José G. B. Derraik ◽  
Wayne S. Cutfield ◽  
Sarah E. Maessen ◽  
Paul L. Hofman ◽  
Timothy Kenealy ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Newly Diagnosed

scholarly journals Diabetic Ketoacidosis Revealing a Severe Hypertriglyceridemia and Acute Pancreatitis in Type 1 Diabetes Mellitus

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Fatima Zahra Zaher ◽  
Imane Boubagura ◽  
Sana Rafi ◽  
Ghizlane Elmghari ◽  
Nawal Elansari
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Biological Evolution ◽  
Intravenous Insulin ◽  
Severe Hypertriglyceridemia ◽  
Metabolic Complication ◽  
Patients With Diabetes

Diabetic ketoacidosis (DKA) is a life-threatening acute metabolic complication occurring in patients with diabetes, especially in patients with type 1 diabetes (T1D), due to an insulin deficiency. Moderate hypertriglyceridemia is commonly observed in DKA but severe hypertriglyceridemia with a triglyceride level exceeding 10g/L is very rarely reported. We report a case of a 14-year-old boy who had type 1 diabetes for 4 years treated with insulin therapy, also having adrenal insufficiency treated with hydrocortisone who presented with ketoacidosis and excruciating abdominal pain. Investigations revealed hypertriglyceridemia at 64g/L, lipasemia at 1000 U/L, and stage E pancreatitis on abdominal CT. The patient was treated with intravenous insulin, rehydration, and fenofibrate with good clinical and biological evolution. Severe hypertriglyceridemia causing pancreatitis in type 1 diabetes mellitus is a rare but very serious complication of DKA in children.

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