Human Centromere Protein C (CENP-C) Is a DNA-Binding Protein Which Possesses a Novel DNA-Binding Motif1

1994 ◽  
Vol 116 (4) ◽  
pp. 877-881 ◽  
Author(s):  
Kenji Sugimoto ◽  
Hiroaki Yata ◽  
Yoshinao Muro ◽  
Michio Himeno
Keyword(s):  
Dna Binding ◽  
Protein C ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Human Centromere ◽  
Centromere Protein

A lateral flow biosensor for rapid detection of DNA-binding protein c-jun

2011 ◽  
Vol 27 (1) ◽  
pp. 192-196 ◽  
Author(s):  
Zhiyuan Fang ◽  
Chenchen Ge ◽  
Wenjuan Zhang ◽  
Puchang Lie ◽  
Lingwen Zeng
Keyword(s):  
Dna Binding ◽  
Rapid Detection ◽  
Protein C ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Lateral Flow

scholarly journals A Centromere DNA-binding Protein from Fission Yeast Affects Chromosome Segregation and Has Homology to Human CENP-B

1997 ◽  
Vol 136 (3) ◽  
pp. 487-500 ◽  
Author(s):  
Dana Halverson ◽  
Mary Baum ◽  
Janet Stryker ◽  
John Carbon ◽  
Louise Clarke
Keyword(s):  
Dna Binding ◽  
Fission Yeast ◽  
Mitotic Chromosome ◽  
Binding Protein ◽  
Chromosome Instability ◽  
Dna Binding Protein ◽  
Autonomously Replicating Sequence ◽  
Human Centromere ◽  
Chromosome Ii

Genetic and biochemical strategies have been used to identify Schizosaccharomyces pombe proteins with roles in centromere function. One protein, identified by both approaches, shows significant homology to the human centromere DNA-binding protein, CENP-B, and is identical to Abp1p (autonomously replicating sequence-binding protein 1) (Murakami, Y., J.A. Huberman, and J. Hurwitz. 1996. Proc. Natl. Acad. Sci. USA. 93:502–507). Abp1p binds in vitro specifically to at least three sites in centromeric central core DNA of S. pombe chromosome II (cc2). Overexpression of abp1 affects mitotic chromosome stability in S. pombe. Although inactivation of the abp1 gene is not lethal, the abp1 null strain displays marked mitotic chromosome instability and a pronounced meiotic defect. The identification of a CENP-B–related centromere DNA-binding protein in S. pombe strongly supports the hypothesis that fission yeast centromeres are structurally and functionally related to the centromeres of higher eukaryotes.

The DNA-binding protein YB-1 is a direct MYCN target and influences repair and resistance in neuroblastoma cell lines

2010 ◽  
Vol 222 (03) ◽  
Author(s):  
S Degen ◽  
S Kuhfittig-Kulle ◽  
JH Schulte ◽  
F Westermann ◽  
A Schramm ◽  
...  
Keyword(s):  
Dna Binding ◽  
Cell Lines ◽  
Binding Protein ◽  
Neuroblastoma Cell ◽  
Dna Binding Protein ◽  
Neuroblastoma Cell Lines
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