Molecular modelling and site-directed mutagenesis of human GALR1 galanin receptor defines determinants of receptor subtype specificity

Receptor Subtype ◽

Directed Mutagenesis ◽

Galanin Receptor ◽

Subtype Specificity

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

Xenobiotica ◽

10.1080/004982598239542 ◽

1998 ◽

Vol 28 (3) ◽

pp. 235-268 ◽

Cited By ~ 50

Author(s):

D. F. V. LEWIS ◽

M. DICKINS ◽

R. J. WEAVER ◽

P. J. EDDERSHAW ◽

P. S. GOLDFARB ◽

...

Keyword(s):

Substrate Specificity ◽

Molecular Modelling ◽

Analysis of structural determinants of the stability of thermolysinlike proteases by molecular modelling and site-directed mutagenesis

Protein Engineering Design and Selection ◽

10.1093/protein/9.12.1181 ◽

1996 ◽

Vol 9 (12) ◽

pp. 1181-1189 ◽

Cited By ~ 29

Author(s):

Oene R. Veltman ◽

Gert Vriend ◽

Pieter J. Middelhoven ◽

Bertus van den Burg ◽

Gerard Venema ◽

...

Keyword(s):

Molecular Modelling ◽

Directed Mutagenesis ◽

Structural Determinants ◽

The Stability

Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling

European Journal of Biochemistry ◽

10.1046/j.1432-1033.2002.03255.x ◽

2002 ◽

Vol 269 (22) ◽

pp. 5522-5526 ◽

Cited By ~ 10

Author(s):

Mónica Salas ◽

Rolando Rodríguez ◽

Nelia López ◽

Elena Uribe ◽

Vasthi López ◽

...

Keyword(s):

Escherichia Coli ◽

Reaction Mechanism ◽

Molecular Modelling ◽

The potential role of glycine-160 of human O6-alkylguanine-DNA alkyltransferase in reaction with O6-benzylguanine as determined by site-directed mutagenesis and molecular modelling comparisons

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ◽

10.1016/s0167-4838(97)00095-2 ◽

1997 ◽

Vol 1342 (1) ◽

pp. 90-102 ◽

Cited By ~ 5

Author(s):

Joseph A Rafferty ◽

Jane E.A Wibley ◽

Peter Speers ◽

Ian Hickson ◽

Geoffrey P Margison ◽

...

Keyword(s):

Molecular Modelling ◽

Potential Role ◽

Directed Mutagenesis ◽

Dna Alkyltransferase

Aminopeptidase B, a glucagon-processing enzyme: site directed mutagenesis of the Zn2+-binding motif and molecular modelling

BMC Biochemistry ◽

10.1186/1471-2091-8-21 ◽

2007 ◽

Vol 8 (1) ◽

pp. 21 ◽

Cited By ~ 17

Author(s):

Viet-Lai Pham ◽

Marie-Sandrine Cadel ◽

Cecile Gouzy-Darmon ◽

Chantal Hanquez ◽

Margery C Beinfeld ◽

...

Keyword(s):

Molecular Modelling ◽

Directed Mutagenesis ◽

Binding Motif ◽

Processing Enzyme

Crucial role of the orexin-B C-terminus in the induction of OX1receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis

British Journal of Pharmacology ◽

10.1111/bph.13287 ◽

2015 ◽

Vol 172 (21) ◽

pp. 5211-5223 ◽

Cited By ~ 6

Author(s):

Pascal Nicole ◽

Pierre Couvineau ◽

Nadege Jamin ◽

Thierry Voisin ◽

Alain Couvineau

Keyword(s):

Molecular Modelling ◽

Crucial Role ◽

Directed Mutagenesis ◽

Alanine Scanning ◽

C Terminus

Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP

Biochemical Journal ◽

10.1042/0264-6021:3490333 ◽

2000 ◽

Vol 349 (1) ◽

pp. 333 ◽

Cited By ~ 7

Author(s):

Gyles COZIER ◽

Richard SESSIONS ◽

Joanna R. BOTTOMLEY ◽

Jon S. REYNOLDS ◽

Peter J. CULLEN

Keyword(s):

Molecular Modelling ◽

Pleckstrin Homology Domain ◽

Directed Mutagenesis ◽

Pleckstrin Homology ◽

Gtpase Activating Protein ◽

Ras Gtpase

Functional characterization of an anti-estradiol antibody by site-directed mutagenesis and molecular modelling: modulation of binding properties and prominent role of the VLdomain in estradiol recognition

Journal of Molecular Recognition ◽

10.1002/jmr.553 ◽

2002 ◽

Vol 15 (1) ◽

pp. 6-18 ◽

Cited By ~ 7

Author(s):

Stéphane Coulon ◽

Jean-Luc Pellequer ◽

Thierry Blachère ◽

Martine Chartier ◽

Elisabeth Mappus ◽

...

Keyword(s):

Molecular Modelling ◽

Functional Characterization ◽

Directed Mutagenesis ◽

Binding Properties

Generation of IL-6 receptor antagonist and super-antagonist by molecular modelling and site-directed mutagenesis

Cytokine ◽

10.1016/1043-4666(94)90184-8 ◽

1994 ◽

Vol 6 (5) ◽

pp. 556

Author(s):

C. Toniatti ◽

A. Lahm ◽

R. Savino ◽

A. Cabibbo ◽

L. Ciapponi ◽

...

Keyword(s):

Receptor Antagonist ◽

Molecular Modelling ◽

Merging crystallography, site-directed mutagenesis and molecular modelling to unravel the regulatory mechanism of photosynthetic GAPDH

Acta Crystallographica Section A Foundations of Crystallography ◽

10.1107/s0108767306097030 ◽

2006 ◽

Vol 62 (a1) ◽

pp. s149-s149

Author(s):

S. Fermani ◽

F. Sparla ◽

G. Falini ◽

L. Martelli ◽

M. Zaffagnini ◽

...

Keyword(s):

Molecular Modelling ◽

Regulatory Mechanism ◽