scholarly journals P102 Building A Better Mousetrap: Expression of Surfactant Protein C (SFTPC) Mutations Induces Dose-Dependent Fibrotic Parenchymal Lung Remodeling In Vivo

QJM ◽  
2016 ◽  
Keyword(s):  
Protein C ◽  
Surfactant Protein ◽  
Surfactant Protein C ◽  
Lung Remodeling ◽  
Dose Dependent ◽  
Parenchymal Lung

BAL Fluid Surfactant Protein C Level Is Related to Parenchymal Lung Disease in Children With Sarcoidosis

CHEST Journal ◽  
2011 ◽  
Vol 140 (4) ◽  
pp. 1104-1105 ◽  
Author(s):  
Loïc Guillot ◽  
Florence Flamein ◽  
Guillaume Thouvenin ◽  
Michèle Boulé ◽  
Hubert Ducou le Pointe ◽  
...  
Keyword(s):  
Lung Disease ◽  
Protein C ◽  
Surfactant Protein ◽  
Surfactant Protein C ◽  
Parenchymal Lung Disease ◽  
Parenchymal Lung

Concentration Dependence of a Poly-Leucine Surfactant Protein C Analogue on in vitro and in vivo Surfactant Activity

Neonatology ◽  
2007 ◽  
Vol 92 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Andreas Almlén ◽  
Guido Stichtenoth ◽  
Bengt Robertson ◽  
Jan Johansson ◽  
Tore Curstedt
Keyword(s):  
Concentration Dependence ◽  
Protein C ◽  
Surfactant Protein ◽  
Surfactant Protein C ◽  
Surfactant Activity

scholarly journals Alterations of the C-terminal end do not affect in vitro or in vivo activity of surfactant protein C analogs

2012 ◽  
Vol 1818 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Andreas Almlén ◽  
Guy Vandenbussche ◽  
Bim Linderholm ◽  
Marie Haegerstrand-Björkman ◽  
Jan Johansson ◽  
...  
Keyword(s):  
Protein C ◽  
Surfactant Protein ◽  
Surfactant Protein C

Surfactant protein C: hormonal control of SP-C mRNA levels in vitro

1992 ◽  
Vol 262 (6) ◽  
pp. L684-L687 ◽  
Author(s):  
S. V. Veletza ◽  
K. V. Nichols ◽  
I. Gross ◽  
H. Lu ◽  
D. W. Dynia ◽  
...  
Keyword(s):  
Hormonal Regulation ◽  
Protein C ◽  
Cdna Probe ◽  
Surfactant Protein ◽  
Hormonal Control ◽  
Mrna Levels ◽  
Cyclic Monophosphate ◽  
Surfactant Protein C ◽  
Dose Dependent Increase ◽  
Dose Dependent

We have studied hormonal regulation of the surfactant protein C (SP-C) in fetal 18-dah rat lung explants. SP-C mRNA was detected in Northern blots with a specific rat SP-C cDNA probe and quantified by densitometry. Treatment of the explants with dexamethasone resulted in a dose-dependent increase of the SP-C mRNA level. Transcriptional assays have shown that the regulation of SP-C mRNA by dexamethasone involves a transcriptional step. Administration of the cAMP analogues, 8-bromoadenosine 3',5'-cyclic monophosphate (8-BrcAMP) or dibutyryl adenosine 3',5'-cyclic monophosphate (DBcAMP), produced a dose-dependent increase of SP-C mRNA levels, with maximum stimulation observed at 200 microM. The thyroid hormone T3 had no effect on SP-C mRNA levels, whether administered alone or in combination with dexamethasone. Variation in the effects of the above hormones on three surfactant protein mRNAs, SP-A, SP-B and SP-C, indicates that the hormonal regulation of the surfactant proteins is a complex process and that each gene is, in part, differentially regulated.

Homozygous mutation in ABCA3 Lipid-Transporter defect (EXON 9) and low level of surfactant protein C

2010 ◽  
Vol 222 (S 01) ◽  
Author(s):  
J Pöschl ◽  
P Ruef ◽  
M Griese ◽  
P Lohse ◽  
C Aslanidis ◽  
...  
Keyword(s):  
Protein C ◽  
Surfactant Protein ◽  
Homozygous Mutation ◽  
Surfactant Protein C ◽  
Low Level ◽  
Exon 9 ◽  
Lipid Transporter

Influence of surfactant protein C on the interfacial behavior of phosphatidylethanolamine monolayers

2008 ◽  
Vol 38 (4) ◽  
pp. 369-379 ◽  
Author(s):  
Albena Jordanova ◽  
Georgi As. Georgiev ◽  
Svobodan Alexandrov ◽  
Roumen Todorov ◽  
Zdravko Lalchev
Keyword(s):  
Protein C ◽  
Surfactant Protein ◽  
Interfacial Behavior ◽  
Surfactant Protein C

scholarly journals TAZ Interacts with TTF-1 and Regulates Expression of Surfactant Protein-C

2004 ◽  
Vol 279 (17) ◽  
pp. 17384-17390 ◽  
Author(s):  
Kwon-Sik Park ◽  
Jeffrey A. Whitsett ◽  
Tina Di Palma ◽  
Jeong-Ho Hong ◽  
Michael B. Yaffe ◽  
...  
Keyword(s):  
Protein C ◽  
Surfactant Protein ◽  
Surfactant Protein C
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