scholarly journals Cognitive Replay of Visuomotor Learning at Sleep Onset: Temporal Dynamics and Relationship to Task Performance

SLEEP ◽  
2010 ◽  
Vol 33 (1) ◽  
pp. 59-68 ◽  
Author(s):  
Erin J. Wamsley ◽  
Karen Perry ◽  
Ina Djonlagic ◽  
Laura Babkes Reaven ◽  
Robert Stickgold
Keyword(s):  
Task Performance ◽  
Temporal Dynamics ◽  
Sleep Onset ◽  
Visuomotor Learning

scholarly journals Concurrent task performance enhances low-level visuomotor learning

2007 ◽  
Vol 69 (4) ◽  
pp. 513-522 ◽  
Author(s):  
Richard A. P. Roche ◽  
Seán Commins ◽  
Francis Agnew ◽  
Sarah Cassidy ◽  
Kristin Corapi ◽  
...  
Keyword(s):  
Task Performance ◽  
Concurrent Task ◽  
Visuomotor Learning ◽  
Low Level

scholarly journals Task performance changes the amplitude and timing of the BOLD signal

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Atae Akhrif ◽  
Maximilian J. Geiger ◽  
Marcel Romanos ◽  
Katharina Domschke ◽  
Susanne Neufang
Keyword(s):  
Task Performance ◽  
Temporal Dynamics ◽  
Brain Activation ◽  
Bold Signal ◽  
Bold Response ◽  
Imaging Data ◽  
Neural Firing ◽  
Beta Band ◽  
Beta Power ◽  
Band Activity

AbstractTranslational studies comparing imaging data of animals and humans have gained increasing scientific interests. With this upcoming translational approach, however, identifying harmonized statistical analysis as well as shared data acquisition protocols and/or combined statistical approaches is necessary. Following this idea, we applied Bayesian Adaptive Regression Splines (BARS), which have until now mainly been used to model neural responses of electrophysiological recordings from rodent data, on human hemodynamic responses as measured via fMRI. Forty-seven healthy subjects were investigated while performing the Attention Network Task in the MRI scanner. Fluctuations in the amplitude and timing of the BOLD response were determined and validated externally with brain activation using GLM and also ecologically with the influence of task performance (i.e. good vs. bad performers). In terms of brain activation, bad performers presented reduced activation bilaterally in the parietal lobules, right prefrontal cortex (PFC) and striatum. This was accompanied by an enhanced left PFC recruitment. With regard to the amplitude of the BOLD-signal, bad performers showed enhanced values in the left PFC. In addition, in the regions of reduced activation such as the parietal and striatal regions, the temporal dynamics were higher in bad performers. Based on the relation between BOLD response and neural firing with the amplitude of the BOLD signal reflecting gamma power and timing dynamics beta power, we argue that in bad performers, an enhanced left PFC recruitment hints towards an enhanced functioning of gamma-band activity in a compensatory manner. This was accompanied by reduced parieto-striatal activity, associated with increased and potentially conflicting beta-band activity.

scholarly journals Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks

2020 ◽  
Author(s):  
Robert Kim ◽  
Terrence J. Sejnowski
Keyword(s):  
Working Memory ◽  
Task Performance ◽  
Cortical Neurons ◽  
Temporal Dynamics ◽  
Single Neurons ◽  
Multiple Timescales ◽  
Neural Data ◽  
Temporal Properties ◽  
Underlying Mechanisms ◽  
Inhibitory Signaling

AbstractCortical neurons process information on multiple timescales, and areas important for working memory (WM) contain neurons capable of integrating information over a long timescale. However, the underlying mechanisms for the emergence of neuronal timescales stable enough to support WM are unclear. By analyzing a spiking recurrent neural network (RNN) model trained on a WM task and activity of single neurons in the primate prefrontal cortex, we show that the temporal properties of our model and the neural data are remarkably similar. Dissecting our RNN model revealed strong inhibitory-to-inhibitory connections underlying a disinhibitory microcircuit as a critical component for long neuronal timescales and WM maintenance. We also found that enhancing inhibitory-to-inhibitory connections led to more stable temporal dynamics and improved task performance. Finally, we show that a network with such microcircuitry can perform other tasks without disrupting its pre-existing timescale architecture, suggesting that strong inhibitory signaling underlies a flexible WM network.

Brain and Body

2011 ◽  
Vol 25 (4) ◽  
pp. 190-200 ◽  
Author(s):  
Sebastian Olbrich ◽  
Christian Sander ◽  
Herbert Matschinger ◽  
Roland Mergl ◽  
Maja Trenner ◽  
...  
Keyword(s):  
Heart Rate ◽  
Time Series ◽  
Regression Analysis ◽  
Temporal Dynamics ◽  
Skin Conductance Level ◽  
Sleep Onset ◽  
Sleep Stages ◽  
Autonomous Nervous System ◽  
Cortical Arousal ◽  
Cross Correlations

The temporal dynamics of electroencephalogram (EEG)-vigilance as a measure of tonic cortical arousal are discussed as pathogenetic factors in neuropsychiatric disorders. Although there is broad knowledge about the interaction of cortical arousal and activity of the autonomous nervous system (ANS) during different sleep stages, the association and temporal interaction between fine-graded EEG-vigilance stages and markers of sympathetic and parasympathetic activity during the transition from wakefulness to sleep onset warrants more detailed exploration and was focus of the presented study. A 15-min resting-EEG, electrocardiogram (ECG), and skin conductance level (SCL) were recorded from 54 healthy subjects. Using an EEG-algorithm (VIGALL), 1-s segments were classified into seven different vigilance stages. Associations and temporal interactions between EEG-vigilance stages and heart rate variability (HRV), heart rate (HR), and SCL were computed using correlation analysis, regression analysis, and cross-correlations of EEG-vigilance and ANS time series. EEG-vigilance stages and ANS activity showed a significant association between increased HRV parameters including total and (normalized) very low frequency power and low vigilance stages. Regression analysis revealed significantly increased values of SCL and HR for high vigilance stages in comparison to lower ones. In these relationships, for SCL but not HR most of the covariance was explained by the effect of time. Phasic increases in EEG-vigilance were paralleled by significant increases of HR but not of SCL. Cross-correlations between EEG-vigilance and ANS time series yielded highest correlations when there was no or only a minimal temporal lag. ANS activity during the transition from wakefulness to sleep onset gradually changes along with different fine-graded EEG-vigilance stages. Associations between cortical and autonomic activity are better reflected by HR than by SCL.

Effects of Concurrent Manual Task Performance on Connected Speech Acoustics in Individuals With Parkinson Disease

2019 ◽  
Vol 62 (7) ◽  
pp. 2099-2117 ◽  
Author(s):  
Jason A. Whitfield ◽  
Zoe Kriegel ◽  
Adam M. Fullenkamp ◽  
Daryush D. Mehta
Keyword(s):  
Task Performance ◽  
Speech Production ◽  
Dual Task ◽  
Motor Task ◽  
Task Condition ◽  
Connected Speech ◽  
Speech Acoustics ◽  
Single Task ◽  
Manual Task ◽  
Task Conditions

Purpose Prior investigations suggest that simultaneous performance of more than 1 motor-oriented task may exacerbate speech motor deficits in individuals with Parkinson disease (PD). The purpose of the current investigation was to examine the extent to which performing a low-demand manual task affected the connected speech in individuals with and without PD. Method Individuals with PD and neurologically healthy controls performed speech tasks (reading and extemporaneous speech tasks) and an oscillatory manual task (a counterclockwise circle-drawing task) in isolation (single-task condition) and concurrently (dual-task condition). Results Relative to speech task performance, no changes in speech acoustics were observed for either group when the low-demand motor task was performed with the concurrent reading tasks. Speakers with PD exhibited a significant decrease in pause duration between the single-task (speech only) and dual-task conditions for the extemporaneous speech task, whereas control participants did not exhibit changes in any speech production variable between the single- and dual-task conditions. Conclusions Overall, there were little to no changes in speech production when a low-demand oscillatory motor task was performed with concurrent reading. For the extemporaneous task, however, individuals with PD exhibited significant changes when the speech and manual tasks were performed concurrently, a pattern that was not observed for control speakers. Supplemental Material https://doi.org/10.23641/asha.8637008

The Influence of Emotionally Relevant Context on the Evoked Cardiac Response Triggered by an Irrelevant Stimulus

2003 ◽  
Vol 17 (2) ◽  
pp. 61-68 ◽  
Author(s):  
Michal Kuniecki ◽  
Robert Barry ◽  
Jan Kaiser
Keyword(s):  
Task Performance ◽  
Auditory Stimulus ◽  
Irrelevant Stimulus ◽  
Cardiac Response ◽  
Mental Task ◽  
Negative Valence ◽  
Cardiac Deceleration ◽  
Relevant Context ◽  
Stimulus Valence ◽  
Affective Stimulus

Abstract The effect of stimulus valence was examined in the evoked cardiac response (ECR) elicited by the exposition of neutral and negative slides as well as by an innocuous auditory stimulus presented on the affective foregrounds generated by the slides. The exposition of the aversive slide produced prolonged cardiac deceleration in comparison with the neutral slide. Similar prolonged deceleration accompanied exposition of the neutral auditory stimulus on the negative visual foreground in comparison with the neutral foreground. We interpret these results as an autonomic correlate of extended stimulus processing associated with the affective stimulus. The initial deceleration response, covering two or three slower heart beats, may be prolonged for several seconds before HR reaches the baseline level again. In such a case the evoked cardiac deceleration can be functionally divided into two parts: the reflexive bradycardia (ECR1) elicited by neutral stimuli and a late decelerative component (LDC). We can speculate that the latter is associated with an additional voluntary continuation of processing of the stimulus. This must involve some cognitive aspect different from the mental task performance which leads to the accelerative ECR2, and we suggest that processing of a stimulus with negative valence is involved in generating the LDC.

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