DUAL ACTING COX‐2 AND SOLUBLE EPOXIDE HYDROLASE INHIBITOR ATTENUATES GLOMERULAR INJURY IN FOCAL SEGMENTAL GLOMERULAR SCLEROSIS

Glomerular Sclerosis ◽

Glomerular Injury ◽

Cox 2 ◽

Soluble Epoxide Hydrolase Inhibitor ◽

EET Analogs and the Dual‐Inhibition of sEH/COX‐2 for the Treatment of Focal Segmental Glomerular Sclerosis

The FASEB Journal ◽

10.1096/fasebj.2019.33.1_supplement.863.8 ◽

2019 ◽

Vol 33 (S1) ◽

Author(s):

Scott D Barnett ◽

Oleg Palygin ◽

Abdul Hye Khan ◽

John D Imig

Keyword(s):

Glomerular Sclerosis ◽

Dual Inhibition ◽

Cox 2 ◽

Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl‐3‐(1‐propionylpiperidin‐4‐yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome‐related pro‐inflammatory and anti‐inflammatory signaling pathways in the lipopolysaccharide‐induced pain mouse model

Drug Development Research ◽

10.1002/ddr.21786 ◽

2021 ◽

Author(s):

Ali Cagli ◽

Sefika Pinar Senol ◽

Meryem Temiz‐Resitoglu ◽

Demet Sinem Guden ◽

Ayse Nihal Sari ◽

...

Keyword(s):

Mouse Model ◽

Signaling Pathways ◽

Epoxide Hydrolase ◽

Inflammatory Signaling ◽

Soluble Epoxide Hydrolase Inhibitor ◽

Anti Inflammatory

Generation of the induced pluripotent stem cell line (NCKDi002-A) from a 22-year-old patient with Focal Segmental Glomerular Sclerosis carrying a heterozygous mutation in WT1 gene

Stem Cell Research ◽

10.1016/j.scr.2021.102293 ◽

2021 ◽

Vol 53 ◽

pp. 102293

Author(s):

Hangdi Wu ◽

Gang Wang ◽

Erzhi Gao ◽

Jing Zhao ◽

Li Zhang ◽

...

Keyword(s):

Stem Cell ◽

Pluripotent Stem Cell ◽

Induced Pluripotent Stem Cell ◽

Glomerular Sclerosis ◽

Heterozygous Mutation ◽

Wt1 Gene ◽

Stem Cell Line ◽

Induced Pluripotent ◽

Health-Related Quality of Life in Focal Segmental Glomerular Sclerosis and Minimal Change Disease: A Qualitative Study of Children and Adults to Inform Patient-Reported Outcomes

Kidney Medicine ◽

10.1016/j.xkme.2021.01.013 ◽

2021 ◽

Author(s):

Noelle E. Carlozzi ◽

Susan F. Massengill ◽

Howard Trachtman ◽

Liron Walsh ◽

Neena Singhal ◽

...

Keyword(s):

Patient Reported Outcomes ◽

Minimal Change Disease ◽

Glomerular Sclerosis ◽

Health Related Quality ◽

Patient Reported ◽

Related Quality ◽

Health Related ◽

THE ROLE OF EPOXYEICOSATRIENOIC ACIDS IN REGULATING ENDOTHELIAL FUNCTION AND THE EFFECTS OF A NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITOR GSK2256294 IN HUMANS

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(16)32309-9 ◽

2016 ◽

Vol 67 (13) ◽

pp. 2308

Author(s):

Lucy Yang ◽

Joseph Cheriyan ◽

Aili Lazaar ◽

Kaisa Maki-Petaja ◽

Ian Wilkinson

Keyword(s):

Endothelial Function ◽

Epoxide Hydrolase ◽

Epoxyeicosatrienoic Acids ◽

Soluble epoxide hydrolase inhibitor, TUPS, attenuates isoproterenol/angiotensin II‐induced cardiac hypertrophy through mammalian target of rapamycin‐mediated autophagy inhibition

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.13113 ◽

2019 ◽

Vol 71 (8) ◽

pp. 1291-1300 ◽

Cited By ~ 3

Author(s):

Huanji Zhang ◽

Kun Zhang ◽

Jianwen Liang ◽

Wen Yan ◽

Fensheng Wu ◽

...

Keyword(s):

Angiotensin Ii ◽

Cardiac Hypertrophy ◽

Epoxide Hydrolase ◽

Mammalian Target Of Rapamycin ◽

Target Of Rapamycin ◽

Soluble Epoxide Hydrolase Inhibitor ◽

Autophagy Inhibition

Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern

Prostaglandins & Other Lipid Mediators ◽

10.1016/j.prostaglandins.2015.06.005 ◽

2015 ◽

Vol 121 ◽

pp. 131-137 ◽

Cited By ~ 33

Author(s):

Annika I. Ostermann ◽

Jan Herbers ◽

Ina Willenberg ◽

Rongjun Chen ◽

Sung Hee Hwang ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Oral Treatment ◽

Drug Levels ◽

Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice

Shock ◽

10.1097/shk.0000000000000767 ◽

2017 ◽

Vol 47 (5) ◽

pp. 638-645 ◽

Cited By ~ 39

Author(s):

Yong Zhou ◽

Tian Liu ◽

Jia-Xi Duan ◽

Ping Li ◽

Guo-Ying Sun ◽

...

Keyword(s):

Acute Lung Injury ◽

Lung Injury ◽

Epoxide Hydrolase ◽

Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor ( t -AUCB): Role of adenosine A 2A receptor and plasma oxylipins

Prostaglandins & Other Lipid Mediators ◽

10.1016/j.prostaglandins.2017.09.001 ◽

2017 ◽

Vol 131 ◽

pp. 83-95 ◽

Cited By ~ 3

Author(s):

Ahmad Hanif ◽

Matthew L. Edin ◽

Darryl C. Zeldin ◽

Christophe Morisseau ◽

John R. Falck ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Reactive Hyperemia ◽

Differential Effects of Combined Soluble Epoxide Hydrolase inhibitor t ‐TUCB and n‐3 Epoxide in Diet‐Induced Obesity

The FASEB Journal ◽

10.1096/fasebj.2021.35.s1.04632 ◽

2021 ◽

Vol 35 (S1) ◽

Author(s):

Yang Yang ◽

Xinyun Xu ◽

Christophe Morisseau ◽

Bruce Hammock ◽

Ahmed Bettaieb ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Differential Effects ◽

Diet Induced Obesity ◽