scholarly journals Gαo proteins regulate the α2A adrenergic receptor‐mediated inhibitory effects of epinephrine in the mouse hippocampal CA3 region

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Brian W Nelson ◽  
Ke Xu ◽  
Brianna Goldenstein ◽  
Jacquline Pribula ◽  
Elizabeth Luger ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Inhibitory Effects ◽  
Hippocampal Ca3 ◽  
Ca3 Region

α2A Adrenergic Receptor Activation Inhibits Epileptiform Activity in the Rat Hippocampal CA3 Region

2007 ◽  
Vol 71 (6) ◽  
pp. 1572-1581 ◽  
Author(s):  
Chris W. D. Jurgens ◽  
Hana M. Hammad ◽  
Jessica A. Lichter ◽  
Sarah J. Boese ◽  
Brian W. Nelson ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Epileptiform Activity ◽  
Receptor Activation ◽  
Hippocampal Ca3 ◽  
Ca3 Region

Effects of beta-adrenergic receptor activation on alveolar macrophage cytoplasmic motility

1993 ◽  
Vol 265 (1) ◽  
pp. L67-L72 ◽  
Author(s):  
T. Fukushima ◽  
K. Sekizawa ◽  
Y. Jin ◽  
M. Yamaya ◽  
H. Sasaki ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Adrenergic Receptor ◽  
Specific Inhibitor ◽  
Lower Lobe ◽  
Receptor Activation ◽  
Maximum Effect ◽  
Inhibitory Effects ◽  
Particle Rotation ◽  
Beta Adrenergic Receptor ◽  
Beta Adrenergic

We studied the effects of fenoterol, a beta-adrenoceptor agonist, on the cytoplasmic motility of alveolar macrophages (AM) from dog lungs in vitro. Four days after the instillation of Fe3O4 particles (3 mg/kg) into the lower lobe bronchus, AM were harvested by bronchoalveolar lavage. Remanent field strength (RFS) from the AM containing Fe3O4 particles (5 x 10(6) cells) was measured immediately after magnetization. RFS decreased with time due to particle rotation (relaxation), which is related to cytoplasmic motility of AM. Fenoterol (10(-9) M to 10(-5) M) decreased the relaxation rate (lambda 0; min-1) in a concentration-dependent fashion with the maximum effect at 10(-6) M. Both forskolin (10(-6) M to 10(-4) M) and dibutyryl adenosine 3',5'-cyclic monophosphate (cAMP) (10(-3) M) mimicked fenoterol-induced inhibitory effects on lambda 0. Fenoterol and forskolin concentration-dependently increased intracellular levels of cAMP, which were parallel to decreases in lambda 0 induced by these drugs. KT 5720 (10(-5) M), a specific inhibitor of protein kinase A, significantly inhibited fenoterol (10(-6) M)-induced inhibitory effects on lambda 0 (P < 0.01). These results imply that beta-adrenergic receptor activation inhibits cytoplasmic motility of AM via increases in intracellular levels of cAMP, which may be coupled with activation of a cAMP-dependent protein kinase.

scholarly journals FK960, a novel cognitive enhancer, increases synapses in the hippocampal CA3 region of aged rats

2000 ◽  
Vol 82 ◽  
pp. 238
Author(s):  
Akira Moriguchi ◽  
Kazuo Nakano ◽  
Kouichi Sano ◽  
Kosei Noda ◽  
Nobuya Matsuoka ◽  
...  
Keyword(s):  
Aged Rats ◽  
Cognitive Enhancer ◽  
Hippocampal Ca3 ◽  
Ca3 Region

β1-and β2-adrenoceptors in hippocampal CA3 region are required for long-term memory consolidation in rats

2015 ◽  
Vol 1627 ◽  
pp. 109-118 ◽  
Author(s):  
Jian Zheng ◽  
Fei Luo ◽  
Nan-nan Guo ◽  
Zong-yue Cheng ◽  
Bao-ming Li
Keyword(s):  
Memory Consolidation ◽  
Long Term Memory ◽  
Term Memory ◽  
Hippocampal Ca3 ◽  
Ca3 Region

Evidence for a Specific Integrative Mechanism for Episodic Memory Mediated by AMPA/kainate Receptors in a Circuit Involving Medial Prefrontal Cortex and Hippocampal CA3 Region

2015 ◽  
Vol 26 (7) ◽  
pp. 3000-3009 ◽  
Author(s):  
Maria A. de Souza Silva ◽  
Joseph P. Huston ◽  
An-Li Wang ◽  
David Petri ◽  
Owen Yuan-Hsin Chao
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory ◽  
Medial Prefrontal Cortex ◽  
Kainate Receptors ◽  
Hippocampal Ca3 ◽  
Ca3 Region

Reactivation with a simple exposure to the experimental environment is sufficient to induce reconsolidation requiring protein synthesis in the hippocampal CA3 region in mice

Hippocampus ◽  
2007 ◽  
Vol 17 (3) ◽  
pp. 181-191 ◽  
Author(s):  
Julien Artinian ◽  
Xavier De Jaeger ◽  
Laetitia Fellini ◽  
Paul de Saint Blanquat ◽  
Pascal Roullet
Keyword(s):  
Protein Synthesis ◽  
Experimental Environment ◽  
Hippocampal Ca3 ◽  
Simple Exposure ◽  
Ca3 Region

Precision and Variability in Postsynaptic Target Selection of Inhibitory Cells in the Hippocampal CA3 Region

1993 ◽  
Vol 5 (12) ◽  
pp. 1729-1751 ◽  
Author(s):  
Attila I. Gulyás ◽  
Richard Mlles ◽  
Norbert Hájos ◽  
Tamás F. Freund
Keyword(s):  
Target Selection ◽  
Hippocampal Ca3 ◽  
Selection Of ◽  
Postsynaptic Target ◽  
Ca3 Region
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