Neural crest cell formation and migration in the developing embryo

1994 ◽  
Vol 8 (10) ◽  
pp. 699-706 ◽  
Author(s):  
Marianne Bronner‐Fraser
Keyword(s):  
Neural Crest ◽  
Cell Formation ◽  
Neural Crest Cell ◽  
And Migration ◽  
Crest Cell

scholarly journals Paladin is an antiphosphatase that regulates neural crest cell formation and migration

2012 ◽  
Vol 371 (2) ◽  
pp. 180-190 ◽  
Author(s):  
Julaine Roffers-Agarwal ◽  
Karla J. Hutt ◽  
Laura S. Gammill
Keyword(s):  
Neural Crest ◽  
Cell Formation ◽  
Neural Crest Cell ◽  
And Migration ◽  
Crest Cell

scholarly journals 03-P132 Xenopus HMGA2 is required for neural crest cell survival and migration

2009 ◽  
Vol 126 ◽  
pp. S106
Author(s):  
Simone Macrí ◽  
Marco Onorati ◽  
Guidalberto Manfioletti ◽  
Robert Vignali
Keyword(s):  
Neural Crest ◽  
Cell Survival ◽  
Neural Crest Cell ◽  
And Migration ◽  
Crest Cell

scholarly journals The Hippo pathway member YAP enhances human neural crest cell fate and migration

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Christopher J. Hindley ◽  
Alexandra Larisa Condurat ◽  
Vishal Menon ◽  
Ria Thomas ◽  
Luis M. Azmitia ◽  
...  
Keyword(s):  
Neural Crest ◽  
Cell Fate ◽  
Hippo Pathway ◽  
Neural Crest Cell ◽  
And Migration ◽  
The Hippo Pathway ◽  
Crest Cell

scholarly journals The methyltransferase NSD3 regulates neural crest cell specification and migration

2010 ◽  
Vol 344 (1) ◽  
pp. 500
Author(s):  
Bridget T. Jacques-Fricke ◽  
Laura S. Gammill
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Specification ◽  
And Migration ◽  
Crest Cell

scholarly journals Neural crest cell migration: requirements for exogenous fibronectin and high cell density.

1983 ◽  
Vol 96 (2) ◽  
pp. 462-473 ◽  
Author(s):  
R A Rovasio ◽  
A Delouvee ◽  
K M Yamada ◽  
R Timpl ◽  
J P Thiery
Keyword(s):  
Cell Adhesion ◽  
Neural Crest ◽  
Type I Collagen ◽  
Neural Crest Cell ◽  
Neural Crest Cells ◽  
Type I ◽  
Cell Adhesion And Migration ◽  
And Migration ◽  
Crest Cell

Cells of the neural crest participate in a major class of cell migratory events during embryonic development. From indirect evidence, it has been suggested that fibronectin (FN) might be involved in these events. We have directly tested the role of FN in neural crest cell adhesion and migration using several in vitro model systems. Avian trunk neural crest cells adhered readily to purified plasma FN substrates and to extracellular matrices containing cellular FN. Their adhesion was inhibited by antibodies to a cell-binding fragment of FN. In contrast, these cells did not adhere to glass, type I collagen, or to bovine serum albumin in the absence of FN. Neural crest cell adhesion to laminin (LN) was significantly less than to FN; however, culturing of crest cells under conditions producing an epithelioid phenotype resulted in cells that could bind equally as well to LN as to FN. The migration of neural crest cells appeared to depend on both the substrate and the extent of cell interactions. Cells migrated substantially more rapidly on FN than on LN or type I collagen substrates; if provided a choice between stripes of FN and glass or LN, cells migrated preferentially on the FN. Migration was inhibited by antibodies against the cell-binding region of FN, and the inhibition could be reversed by a subsequent addition of exogenous FN. However, the migration on FN was random and displayed little persistence of direction unless cells were at high densities that permitted frequent contacts. The in vitro rate of migration of cells on FN-containing matrices was 50 microns/h, similar to their migration rates along the narrow regions of FN-containing extracellular matrix in migratory pathways in vivo. These results indicate that FN is important for neural crest cell adhesion and migration and that the high cell densities of neural crest cells in the transient, narrow migratory pathways found in the embryo are necessary for effective directional migration.

DIFFERENTIAL NEURAL CREST CELL ATTACHMENT AND MIGRATION ON AVIAN LAMININ ISOFORMS

1996 ◽  
Vol 14 (3) ◽  
pp. 297-314 ◽  
Author(s):  
Roberto Perris ◽  
Ralph Brandenberger ◽  
Matthias Chiquet
Keyword(s):  
Neural Crest ◽  
Cell Attachment ◽  
Neural Crest Cell ◽  
And Migration ◽  
Crest Cell

scholarly journals ALX 1‐ related frontonasal dysplasia results from defective neural crest cell development and migration

2020 ◽  
Vol 12 (10) ◽  
Author(s):  
Jonathan Pini ◽  
Janina Kueper ◽  
Yiyuan David Hu ◽  
Kenta Kawasaki ◽  
Pan Yeung ◽  
...  
Keyword(s):  
Neural Crest ◽  
Neural Crest Cell ◽  
Cell Development ◽  
Frontonasal Dysplasia ◽  
And Migration ◽  
Crest Cell
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