The Quantitative Determination of Cerebral Blood Flow in Man by the Use of Nitrous Oxide in Low Concentrations

1944 ◽  
Vol 208 (6) ◽  
pp. 809 ◽  
Author(s):  
SEYMOUR S. KETY ◽  
CARL F. SCHMIDT
Keyword(s):  
Blood Flow ◽  
Nitrous Oxide ◽  
Cerebral Blood Flow ◽  
Quantitative Determination ◽  
Low Concentrations

The paper that completely altered our thinking about cerebral blood flow measurement

2004 ◽  
Vol 97 (5) ◽  
pp. 1601-1602 ◽  
Author(s):  
Richard J. Traystman
Keyword(s):  
Blood Flow ◽  
Nitrous Oxide ◽  
Cerebral Blood Flow ◽  
Flow Measurement ◽  
Blood Flow Measurement ◽  
Cerebral Blood Flow Measurement ◽  
Low Concentrations

Kety SS and Schmidt CF. The determination of cerebral blood flow in man by the use of nitrous oxide in low concentrations. Am J Physiol 143: 53—66, 1945 ( http://ajplegacy.physiology.org/cgi/reprint/143/1/53 ).

scholarly journals Quantitative determination of cerebral blood flow

1971 ◽  
Vol 2 (10) ◽  
pp. 1351-1359 ◽  
Author(s):  
Yoshiaki Tazaki ◽  
Tohru Sawada
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Quantitative Determination

Tc-99m HMPAO/SPECT Determination of Regional Cerebral Blood Flow Changes in Schizophrenics

1990 ◽  
Vol 15 (12) ◽  
pp. 904-907 ◽  
Author(s):  
BELKIS ERBAS ◽  
HAKAN KUMBASAR ◽  
G??NAYDIN ERBENGI ◽  
COSKUN BEKDIK
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Flow Changes

scholarly journals Use of 19F NMR Spectroscopy for Measurement of Cerebral Blood Flow: A Comparative Study Using Microspheres

1989 ◽  
Vol 9 (6) ◽  
pp. 886-891 ◽  
Author(s):  
David Barranco ◽  
Leslie N. Sutton ◽  
Sandra Florin ◽  
Joel Greenberg ◽  
Teresa Sinnwell ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Blood ◽  
Radioactive Microsphere ◽  
Low Concentrations ◽  
Cat Brain ◽  
Nmr Techniques ◽  
High Concentrations ◽  
Washout Curves ◽  
The Brain

19F NMR was used to determine washout curves of an inert, diffusible gas (CHF3) from the cat brain. The cerebral blood flow was estimated from a bi- or tri-phasic fit to the deconvoluted wash-out curve, using the Kety-Schmidt approach. Cerebral blood flow values determined by 19F NMR show the expected responsiveness to alterations in Paco2, but are approximately 28% lower than cerebral blood flow values determined simultaneously by radioactive microsphere techniques. High concentrations of CHF3 have little effect on intracranial pressure, mean arterial blood pressure or Paco2, but cause small changes in the blood flow to certain regions of the brain. We conclude that 19F NMR techniques utilizing low concentrations of CHF3 have potential for the noninvasive measurement of cerebral blood flow.

Sign in / Sign up

Export Citation Format

Share Document