Lambert-Eaton Myasthenic Syndrome Associated with Idiopathic Thrombocytopenic Purpura and Diffuse Panbronchiolitis: Long-Term Remission after a Course of Intravenous Immunoglobulin Combined with Low-Dose Prednisolone

1999 ◽  
Vol 318 (5) ◽  
pp. 353 ◽  
Author(s):  
T. TAKATA ◽  
S. KOIDE ◽  
K. OGATA ◽  
M. MOTOMURA ◽  
T. YOSHIMURA ◽  
...  
Keyword(s):  
Intravenous Immunoglobulin ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Low Dose ◽  
Thrombocytopenic Purpura ◽  
Diffuse Panbronchiolitis ◽  
Myasthenic Syndrome

scholarly journals A Case of Pregnancy Complicated with Evans Syndrome with Sequential Development of Autoimmune Warm Antibody Hemolytic Anemia and Idiopathic Thrombocytopenic Purpura

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Haruka Suzuki ◽  
Koji Yamanoi ◽  
Jumpei Ogura ◽  
Takahiro Hirayama ◽  
Koji Yasumoto ◽  
...  
Keyword(s):  
Hemolytic Anemia ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Macrocytic Anemia ◽  
Evans Syndrome ◽  
Thrombocytopenic Purpura ◽  
Sequential Development ◽  
Healthy Female ◽  
Long Term Follow Up ◽  
Haptoglobin Level

The simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP) is known as Evans syndrome. We experienced a case of Evans syndrome that developed AIHA during pregnancy and ITP long after delivery. The patient was a 35-year-old pregnant woman (gravida 2, para 1). A routine blood test at 28 weeks of gestation revealed moderate macrocytic anemia. Her haptoglobin level was markedly low, and a direct antiglobulin test (DAT) was positive. Based on these results, AIHA was considered. A healthy female newborn with bodyweight 3575 g was vaginally delivered uneventfully. After delivery, the DAT remained positive, but anemia did not develop. At 203 days after delivery, ITP was detected. Because AIHA and ITP developed sequentially, she was diagnosed with Evans syndrome. When AIHA occurs during pregnancy, long-term follow-up is needed because ITP can develop sequentially.

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