scholarly journals A Case of Pregnancy Complicated with Evans Syndrome with Sequential Development of Autoimmune Warm Antibody Hemolytic Anemia and Idiopathic Thrombocytopenic Purpura

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Haruka Suzuki ◽  
Koji Yamanoi ◽  
Jumpei Ogura ◽  
Takahiro Hirayama ◽  
Koji Yasumoto ◽  
...  
Keyword(s):  
Hemolytic Anemia ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Macrocytic Anemia ◽  
Evans Syndrome ◽  
Thrombocytopenic Purpura ◽  
Sequential Development ◽  
Healthy Female ◽  
Long Term Follow Up ◽  
Haptoglobin Level

The simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP) is known as Evans syndrome. We experienced a case of Evans syndrome that developed AIHA during pregnancy and ITP long after delivery. The patient was a 35-year-old pregnant woman (gravida 2, para 1). A routine blood test at 28 weeks of gestation revealed moderate macrocytic anemia. Her haptoglobin level was markedly low, and a direct antiglobulin test (DAT) was positive. Based on these results, AIHA was considered. A healthy female newborn with bodyweight 3575 g was vaginally delivered uneventfully. After delivery, the DAT remained positive, but anemia did not develop. At 203 days after delivery, ITP was detected. Because AIHA and ITP developed sequentially, she was diagnosed with Evans syndrome. When AIHA occurs during pregnancy, long-term follow-up is needed because ITP can develop sequentially.

scholarly journals A RARE CASE REPORT OF EVANS SYNDROME IN PREGNANCY

2020 ◽  
pp. 1-2
Author(s):  
T. Susmitha* ◽  
G. Nirmala Vani
Keyword(s):  
Rare Case ◽  
Macrocytic Anemia ◽  
Evans Syndrome ◽  
Thrombocytopenic Purpura ◽  
Serum Haptoglobin ◽  
Sequential Development ◽  
Healthy Female ◽  
Antiglobulin Test ◽  
Rare Case Report ◽  
In Pregnancy

The simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP) is known as Evans syndrome,which is very rare in pregnancy.We experienced a case of Evans syndrome in pregnancy.A 23-year-old primigravida with 37 weeks of gestation presented to the labor room with Evans syndrome. Her blood reports revealed features of hemolysis with macrocytic anemia, thrombocytopenia, elevated LDH, and low serum haptoglobin levels, and a direct antiglobulin test (DAT) was positive. A healthy female newborn with 3200 g was delivered by cesarean section.After delivery, DAT remained positive, and her platelet count falls markedly, and bone marrow transplantation was done.When Evans syndrome diagnosed during pregnancy, close and careful observation is essential because it can worsen both the maternal and fetal condition.

Long-Term Follow-Up of Adult Patients with Idiopathic Thrombocytopenic Purpura after Splenectomy

2011 ◽  
Vol 4 (3) ◽  
pp. 285-289 ◽  
Author(s):  
Marica Pavkovic ◽  
Slobodanka Trpkovska-Terzieva ◽  
Arif Latifi ◽  
Oliver Karanfilski ◽  
Lidija Cevreska ◽  
...  
Keyword(s):  
Idiopathic Thrombocytopenic Purpura ◽  
Adult Patients ◽  
Thrombocytopenic Purpura ◽  
Long Term Follow Up

scholarly journals Evans Syndrome in Childhood: Long Term Follow-Up and the Evolution in Primary Immunodeficiency or Rheumatological Disease

2019 ◽  
Vol 7 ◽  
Author(s):  
Beatrice Rivalta ◽  
Daniele Zama ◽  
Giovanni Pancaldi ◽  
Elena Facchini ◽  
Maria Elena Cantarini ◽  
...  
Keyword(s):  
Primary Immunodeficiency ◽  
Evans Syndrome ◽  
Long Term Follow Up ◽  
Rheumatological Disease
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