Further Characterization of the Receptor Mechanism Involved in the Antidysrhythmic Effect of Dexmedetomidine on Halothane/Epinephrine Dysrhythmias in Dogs
1995 ◽
Vol 83
(5)
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pp. 1082-1089
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Keyword(s):
Abstract Background alpha2Adrenoceptors in the central nervous system mediate various physiologic processes, including cardiovascular control. Recently, some of these actions have been reported to be mediated by a nonadrenergic receptor, namely an imidazoline receptor. The authors previously reported that dexmedetomidine, a selective alpha2agonist, prevents the genesis of halothane-epinephrine dysrhythmias through a central mechanism. Because dexmedetomidine also binds to imidazoline receptors, we performed the current study to examine the precise receptor mechanism involved in the antidysrhythmic property of dexmedetomidine.
1980 ◽
Vol 5
(1)
◽
pp. 18-21
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2021 ◽
1996 ◽
Vol 37
(1-2)
◽
pp. 1-14
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1981 ◽
Vol 13
(1)
◽
pp. 30-35
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