Attention-dependent allocation of auditory processing resources as measured by mismatch negativity

Neuroreport ◽  
1999 ◽  
Vol 10 (18) ◽  
pp. 3749-3753 ◽  
Author(s):  
Alexandra Dittmann-Balcar ◽  
Renate Thienel ◽  
Ulrich Schall
2004 ◽  
Vol 25 (3) ◽  
pp. 284-301 ◽  
Author(s):  
Catharine M. Pettigrew ◽  
Bruce E. Murdoch ◽  
Curtis W. Ponton ◽  
Simon Finnigan ◽  
Paavo Alku ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Yang Wenyi Liu ◽  
Bing Wang ◽  
Bing Chen ◽  
John J. Galvin ◽  
Qian-Jie Fu

AbstractMany tinnitus patients report difficulties understanding speech in noise or competing talkers, despite having “normal” hearing in terms of audiometric thresholds. The interference caused by tinnitus is more likely central in origin. Release from informational masking (more central in origin) produced by competing speech may further illuminate central interference due to tinnitus. In the present study, masked speech understanding was measured in normal hearing listeners with or without tinnitus. Speech recognition thresholds were measured for target speech in the presence of multi-talker babble or competing speech. For competing speech, speech recognition thresholds were measured for different cue conditions (i.e., with and without target-masker sex differences and/or with and without spatial cues). The present data suggest that tinnitus negatively affected masked speech recognition even in individuals with no measurable hearing loss. Tinnitus severity appeared to especially limit listeners’ ability to segregate competing speech using talker sex differences. The data suggest that increased informational masking via lexical interference may tax tinnitus patients’ central auditory processing resources.


2014 ◽  
Vol 75 (6) ◽  
pp. 459-469 ◽  
Author(s):  
Veronica B. Perez ◽  
Scott W. Woods ◽  
Brian J. Roach ◽  
Judith M. Ford ◽  
Thomas H. McGlashan ◽  
...  

2012 ◽  
Vol 123 (3) ◽  
pp. 424-458 ◽  
Author(s):  
R. Näätänen ◽  
T. Kujala ◽  
C. Escera ◽  
T. Baldeweg ◽  
K. Kreegipuu ◽  
...  

2019 ◽  
Vol 24 (02) ◽  
pp. e154-e159
Author(s):  
Mirtes Brückmann ◽  
Michele Vargas Garcia

Abstract Introduction Mismatch negativity (MMN) is a long latency auditory evoked potential, represented by a negative wave, generated after the potential N1 and visualized in a resulting wave. Objective To identify the time of occurrence of MMN after N1, elicited with verbal and nonverbal stimuli. Methods Ninety individuals aged between 18 and 56 years old participated in the study, 39 of whom were male and 51 female, with normal auditory thresholds, at least 8 years of schooling, and who did not present auditory processing complaints. All of them underwent audiologic anamnesis, visual inspection of external auditory meatus, pure tone audiometry, speech audiometry, acoustic immittance measures and the dichotic sentence identification test as a screening for alterations in auditory processing, a requirement to participate in the sample. The MMN was applied with two different stimuli, with these being da/ta (verbal) and 750 Hz and 1,000 Hz (nonverbal). Results There was a statistically significant difference between the latency values of the N1 potential and the MMN with the two stimuli, as well as between the MMN with verbal and nonverbal stimuli, and the latency of the MMN elicited with da/ta being greater than that elicited with 750 Hz and 1,000 Hz, which facilitated its visualization. Conclusion The time of occurrence of MMN after the N1 elicited with verbal stimuli was 100.4 ms and with nonverbal stimuli 85.5 ms. Thus, the marking of the MMN with verbal stimuli proved to be more distant from N1 compared with the nonverbal stimuli.


2009 ◽  
Vol 21 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Guo-zhen Yuan ◽  
Zhen-he Zhou ◽  
Jian-jun Yao

Objective:The purpose of this study was to investigate whether the effects of quetiapine on abnormalities of early auditory processing in patients with schizophrenia were reflected by mismatch negativity (MMN).Methods:Subjects were 23 patients with schizophrenia and 23 controls. Psychopathology was rated in patients with the Positive and Negative Syndrome Scale (PANSS) at baseline and after 4-week and after 8-week treatments with quetiapine. Auditory stimuli for event-related potentials consisted of 100 ms/1000 Hz standards, intermixed with 100 ms/1500 Hz frequency deviants and 250 ms/ 1000 Hz duration deviants. A stimulus onset asynchrony of each was 300 ms. Electroencephalograph was recorded at Fz. BESA 5.1.8 was used to perform data analysis. MMN waveforms were obtained by subtracting waveforms elicited by standards from those elicited by frequency- or duration-deviant stimuli.Results:Quetiapine decreased all PANSS scores. Patients showed smaller mean amplitudes of frequency and duration MMN at baseline than did controls. A repeated measure analysis of variance with sessions (i.e. baseline and 4- and 8-week treatments) and MMN type (frequency versus duration) as within-subject factors revealed no significant MMN type or MMN type × session main effect for MMN amplitudes (for MMN type: F = 0.704, df = 1, p = 0.403; for MMN type × session: F = 0.299, df = 2, p = 0.796). Session main effect was significant (F = 3.576, df = 2, p = 0.031). Least square difference tests showed significant differences between MMN amplitudes at 8 weeks and those at both baseline (p = 0.025) and 4 weeks (p = 0.020). MMN amplitudes at 8 weeks were higher than those at baseline.Conclusions:Quetiapine improved the amplitudes of MMN after the 8-week treatment. MMN offers objective evidence that treatment with the quetiapine may ameliorate preattentive deficits in schizophrenia.


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