Immunological, virological and clinical response to highly active antiretroviral therapy treatment regimens in a complete clinic population

AIDS ◽  
2000 ◽  
Vol 14 (11) ◽  
pp. 1545-1552 ◽  
Author(s):  
Amanda Mocroft ◽  
Helen Devereux ◽  
Sabine Kinloch-de-Loes ◽  
Debbie Wilson ◽  
Sara Madge ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Clinical Response ◽  
Highly Active Antiretroviral Therapy ◽  
Treatment Regimens ◽  
Highly Active ◽  
Clinic Population ◽  
Therapy Treatment

scholarly journals Persistent Kaposi sarcoma in the era of highly active antiretroviral therapy: characterizing the predictors of clinical response

AIDS ◽  
2008 ◽  
Vol 22 (8) ◽  
pp. 937-945 ◽  
Author(s):  
Huong Q Nguyen ◽  
Amalia S Magaret ◽  
Mari M Kitahata ◽  
Stephen E Van Rompaey ◽  
Anna Wald ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Clinical Response ◽  
Highly Active Antiretroviral Therapy ◽  
Kaposi Sarcoma ◽  
Highly Active

Virologic, Immunologic, and Clinical Response to Highly Active Antiretroviral Therapy: the Gender Issue Revisited

2003 ◽  
Vol 32 (4) ◽  
pp. 452-461 ◽  
Author(s):  
Antonia L. Moore ◽  
Ole Kirk ◽  
Anne M. Johnson ◽  
Christine Katlama ◽  
Anders Blaxhult ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Clinical Response ◽  
Highly Active Antiretroviral Therapy ◽  
Gender Issue ◽  
Highly Active

An emerging severe leukoencephalopathy: is it due to HIV disease or highly active antiretroviral therapy?

2006 ◽  
Vol 17 (3) ◽  
pp. 205-207 ◽  
Author(s):  
Simon Rackstraw ◽  
Jeanette Meadway ◽  
James Bingham ◽  
Safa Al-Sarraj ◽  
Ian Everall
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Clinical Response ◽  
Highly Active Antiretroviral Therapy ◽  
Immune Reconstitution ◽  
Undetectable Viral Load ◽  
Hiv Disease ◽  
Good Clinical Response ◽  
Highly Active ◽  
The Brain

We report an individual who had HIV-associated dementia, but a good clinical response to antiretroviral therapy, with a rising CD4 count and undetectable viral load. A severe leukoencephalopathy was noted at postmortem; however, no HIV immunopositive cells were found in the brain, suggesting that this new severe leukoencephalopathy is associated with immune reconstitution.

HIV-1 RNA, CD4 T-lymphocytes, and clinical response to highly active antiretroviral therapy

AIDS ◽  
2001 ◽  
Vol 15 (17) ◽  
pp. 2251-2257 ◽  
Author(s):  
Timothy R. Sterling ◽  
Richard E. Chaisson ◽  
Richard D. Moore
Keyword(s):  
Antiretroviral Therapy ◽  
T Lymphocytes ◽  
Clinical Response ◽  
Highly Active Antiretroviral Therapy ◽  
Highly Active ◽  
Hiv 1

scholarly journals Immunological and Virological Failure among Individuals on Highly-Active Antiretroviral Therapy

2021 ◽  
Author(s):  
Hadush Negash ◽  
Brhane Berhe ◽  
Miglas Welay
Keyword(s):  
Drug Resistance ◽  
Viral Load ◽  
Antiretroviral Therapy ◽  
Treatment Failure ◽  
Virological Failure ◽  
Highly Active Antiretroviral Therapy ◽  
Antiretroviral Treatment ◽  
Mortality And Morbidity ◽  
Treatment Regimens ◽  
Highly Active

Initiation of antiretroviral treatment decreased HIV related mortality and morbidity. Virological failure (a condition defined when the plasma viral load of HIV infected individuals greater than 1000 RNA copies/ml based on two consecutive viral load measurements with adherence support) have an increased risk of clinical progression to acquired immune deficiency syndrome (AIDS) and death. Nowadays, combination of highly active antiretroviral therapy is recommended to decrease the likelihood of drug resistance. However, there is emergence of drug resistance and treatment failure during treatment. Hence, managing and detecting antiretroviral treatment response is important to monitor the effectiveness of medication and possible drug switching for treatment regimens. Additionally, mechanisms of drug resistance and factors associated with immunological and virological treatment failure should be addressed.

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