A COMPUTATIONAL MODEL OF BLOOD FLOW AND AORTIC WALL STRESS IN ABDOMINAL AORTIC ANEURYSMS

ASAIO Journal ◽  
1999 ◽  
Vol 45 (2) ◽  
pp. 197
Author(s):  
P J Cabrales ◽  
J E Gómez ◽  
J Camacho ◽  
C Espinel ◽  
J C Briceño
2000 ◽  
Author(s):  
Mano J. Thubrikar ◽  
Michel Labrosse ◽  
Jihad Al-Soudi ◽  
Brett Fowler ◽  
Francis Robicsek

Abstract Abdominal aortic aneurysms (AAA) rupture when the aortic wall cannot withstand the stresses and strains induced by the pulsatile blood pressure. In recent years, different mechanical models of aneurysms have been presented (Vorp et al., 1998, Di Martino et al., 1998, Thubrikar et al., 1999). Although powerful modeling tools such as finite elements are available, there is still a need for experimental data concerning the mechanical properties of the aneurysm wall.


PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192032 ◽  
Author(s):  
Dara Azar ◽  
Donya Ohadi ◽  
Alexander Rachev ◽  
John F. Eberth ◽  
Mark J. Uline ◽  
...  

2004 ◽  
Vol 126 (4) ◽  
pp. 438-446 ◽  
Author(s):  
Robert A. Peattie ◽  
Tiffany J. Riehle ◽  
Edward I. Bluth

As one important step in the investigation of the mechanical factors that lead to rupture of abdominal aortic aneurysms, flow fields and flow-induced wall stress distributions have been investigated in model aneurysms under pulsatile flow conditions simulating the in vivo aorta at rest. Vortex pattern emergence and evolution were evaluated, and conditions for flow stability were delineated. Systolic flow was found to be forward-directed throughout the bulge in all the models, regardless of size. Vortices appeared in the bulge initially during deceleration from systole, then expanded during the retrograde flow phase. The complexity of the vortex field depended strongly on bulge diameter. In every model, the maximum shear stress occurred at peak systole at the distal bulge end, with the greatest shear stress developing in a model corresponding to a 4.3 cm AAA in vivo. Although the smallest models exhibited stable flow throughout the cycle, flow in the larger models became increasingly unstable as bulge size increased, with strong amplification of instability in the distal half of the bulge. These data suggest that larger aneurysms in vivo may be subject to more frequent and intense turbulence than smaller aneurysms. Concomitantly, increased turbulence may contribute significantly to wall stress magnitude and thereby to risk of rupture.


2008 ◽  
Vol 47 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Michael S. Heng ◽  
Michael J. Fagan ◽  
Jason W. Collier ◽  
Grishma Desai ◽  
Peter T. McCollum ◽  
...  

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