Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock

1997 ◽  
Vol 25 (9) ◽  
pp. 1588-1593 ◽  
Author(s):  
Brian Krafte-Jacobs ◽  
Richard Brilli ◽  
Csaba Szabo ◽  
Alvin Denenberg ◽  
Lori Moore ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Septic Shock ◽  
Critically Ill ◽  
Critically Ill Children ◽  
Nitrate Concentrations ◽  
Nitrite Nitrate

scholarly journals Septic shock and vasopressor requirement is associated with lower vitamin D levels in critically ill children

Critical Care ◽  
2011 ◽  
Vol 15 (S3) ◽  
Author(s):  
K Madden ◽  
HA Feldman ◽  
E Smith ◽  
CM Gordon ◽  
S Keisling ◽  
...  
Keyword(s):  
Vitamin D ◽  
Septic Shock ◽  
Critically Ill ◽  
Critically Ill Children ◽  
Vitamin D Levels ◽  
Lower Vitamin

scholarly journals The Association Between Vitamin E Deficiency and Critically Ill Children With Sepsis and Septic Shock

2021 ◽  
Vol 8 ◽  
Author(s):  
Hongxing Dang ◽  
Jing Li ◽  
Chengjun Liu ◽  
Feng Xu
Keyword(s):  
Septic Shock ◽  
Vitamin E ◽  
Critically Ill ◽  
Serum Vitamin ◽  
Independent Effect ◽  
Critically Ill Children ◽  
Vitamin E Deficiency ◽  
Suspected Infection ◽  
Sepsis And Septic Shock ◽  
Vitamin E Status

Background: Literature is scarce on the assessment of vitamin E status in septic children. We aim to investigate the prevalence of vitamin E deficiency in critically ill children with sepsis and septic shock and its association with clinical features and outcomes.Methods: We compared serum vitamin E status between the confirmed or suspected infection and no infection groups, the sepsis shock and no sepsis shock groups upon pediatric intensive care unit admission. Clinical characteristics were compared in subgroup patients with and without vitamin E deficiency. The association between vitamin E deficiency and septic shock were evaluated using univariate and multivariable methods.Results: 182 critically ill children with confirmed or suspected infection and 114 without infection were enrolled. The incidence of vitamin E deficiency was 30.2% in the infection group and 61.9% in the septic shock subgroup (P < 0.001). Thirty-days mortality in critically ill children with vitamin E deficiency was significantly higher than that without vitamin E deficiency (27.3 vs. 14.2%, P < 0.05). Vitamin E levels were inversely associated with higher pediatric risk of mortality (r = − 0.238, P = 0.001) and cardiovascular sequential organ failure assessment (r = −0.249, p < 0.001) scores in critically ill children with infection. In multivariable logistic regression, vitamin E deficiency showed an independent effect on septic shock (adjusted OR: 6.749, 95%CI: 2.449–18.60, P < 0.001).Conclusion: Vitamin E deficiency is highly prevalent in critically ill children with sepsis and contributed to the septic shock.

Effect of l-NAME, an inhibitor of nitric oxide synthesis, on plasma levels of IL-6, IL-8, TNFα and nitrite/nitrate in human septic shock

1998 ◽  
Vol 24 (7) ◽  
pp. 673-679 ◽  
Author(s):  
J. A. M. Avontuur ◽  
T. C. Stam ◽  
A. M. M. Eggermont ◽  
H. A. Braining ◽  
M. Jongen-Lavrencic ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Septic Shock ◽  
Plasma Levels ◽  
Nitric Oxide Synthesis ◽  
Human Septic Shock ◽  
Nitrite Nitrate

scholarly journals Effectiveness of predicting outcome in septic shock in critically ill children by assessing serum lactate levels

2016 ◽  
Vol 3 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Dr. Jasashree Choudhury ◽  
◽  
Dr. Sidharth Sraban Routray ◽  
Dr Laxmidhar Dash ◽  
◽  
...  
Keyword(s):  
Septic Shock ◽  
Critically Ill ◽  
Serum Lactate ◽  
Critically Ill Children ◽  
Predicting Outcome ◽  
Lactate Levels

Plasma Levels of Nitric Oxide and Carbon Monoxide in Critically Ill Children with Septic Syndrome

2007 ◽  
Vol 7 (5) ◽  
pp. 769-775
Author(s):  
Tarek A. Abd El-Gaw ◽  
Sally A.F. El-Sahrig . ◽  
Azza M.O. Abdel-Rahm . ◽  
Esmat Abdel Ghaffar . ◽  
Enas Abd El-Rasheed .
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Critically Ill ◽  
Plasma Levels ◽  
Critically Ill Children ◽  
Septic Syndrome
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