THE EFFECT OF HELIUM-OXYGEN GAS MIXTURE ON DELIVERED FIO2 AND TIDAL VOLUME DURING HIGH FREQUENCY OSCILLATORY VENTILATION

2002 ◽  
Vol 30 (Supplement) ◽  
pp. A85
Author(s):  
Raymond J Parungao ◽  
Jose Luis Olarte ◽  
Bala R Totapally ◽  
Andre Raszynski
Keyword(s):  
Tidal Volume ◽  
High Frequency ◽  
High Frequency Oscillatory Ventilation ◽  
Gas Mixture ◽  
Oscillatory Ventilation ◽  
Oxygen Gas ◽  
High Frequency Oscillatory

scholarly journals Physiologic responses to a staircase lung volume optimization maneuver in pediatric high-frequency oscillatory ventilation

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Pauline de Jager ◽  
Johannes G. M. Burgerhof ◽  
Alette A. Koopman ◽  
Dick G. Markhorst ◽  
Martin C. J. Kneyber
Keyword(s):  
Tidal Volume ◽  
Lung Volume ◽  
High Frequency ◽  
Hemodynamic Instability ◽  
High Frequency Oscillatory Ventilation ◽  
Pressure Amplitude ◽  
Oscillatory Ventilation ◽  
Arterial Blood ◽  
Respiratory Inductance Plethysmography ◽  
High Frequency Oscillatory

Abstract Background Titration of the continuous distending pressure during a staircase incremental–decremental pressure lung volume optimization maneuver in children on high-frequency oscillatory ventilation is traditionally driven by oxygenation and hemodynamic responses, although validity of these metrics has not been confirmed. Methods Respiratory inductance plethysmography values were used construct pressure–volume loops during the lung volume optimization maneuver. The maneuver outcome was evaluated by three independent investigators and labeled positive if there was an increase in respiratory inductance plethysmography values at the end of the incremental phase. Metrics for oxygenation (SpO2, FiO2), proximal pressure amplitude, tidal volume and transcutaneous measured pCO2 (ptcCO2) obtained during the incremental phase were compared between outcome maneuvers labeled positive and negative to calculate sensitivity, specificity, and the area under the receiver operating characteristic curve. Ventilation efficacy was assessed during and after the maneuver by measuring arterial pH and PaCO2. Hemodynamic responses during and after the maneuver were quantified by analyzing heart rate, mean arterial blood pressure and arterial lactate. Results 41/54 patients (75.9%) had a positive maneuver albeit that changes in respiratory inductance plethysmography values were very heterogeneous. During the incremental phase of the maneuver, metrics for oxygenation and tidal volume showed good sensitivity (> 80%) but poor sensitivity. The sensitivity of the SpO2/FiO2 ratio increased to 92.7% one hour after the maneuver. The proximal pressure amplitude showed poor sensitivity during the maneuver, whereas tidal volume showed good sensitivity but poor specificity. PaCO2 decreased and pH increased in patients with a positive and negative maneuver outcome. No new barotrauma or hemodynamic instability (increase in age-adjusted heart rate, decrease in age-adjusted mean arterial blood pressure or lactate > 2.0 mmol/L) occurred as a result of the maneuver. Conclusions Absence of improvements in oxygenation during a lung volume optimization maneuver did not indicate that there were no increases in lung volume quantified using respiratory inductance plethysmography. Increases in SpO2/FiO2 one hour after the maneuver may suggest ongoing lung volume recruitment. Ventilation was not impaired and there was no new barotrauma or hemodynamic instability. The heterogeneous responses in lung volume changes underscore the need for monitoring tools during high-frequency oscillatory ventilation.

New Ventilator Strategies: High-Frequency Oscillatory Ventilation Combined with Volume Guarantee

2018 ◽  
Vol 35 (06) ◽  
pp. 545-548 ◽  
Author(s):  
N. González-Pacheco ◽  
J. Belik ◽  
M. Santos ◽  
F. Tendillo ◽  
M. Sánchez-Luna
Keyword(s):  
Tidal Volume ◽  
High Frequency ◽  
Animal Studies ◽  
Newborn Infants ◽  
High Frequency Oscillatory Ventilation ◽  
Very High Frequency ◽  
Oscillatory Ventilation ◽  
New Strategy ◽  
Lung Trauma ◽  
High Frequency Oscillatory

AbstractHigh-frequency oscillatory ventilation (HFOV) has been proposed as an alternative method of invasive ventilation in immature infants to prevent ventilator lung injury. To better control the size of the high-frequency tidal volume and to prevent large tidal volumes, a new strategy of controlling the tidal volume during HFOV (VThf) has been developed, HFOV–volume guarantee (VG). Data from preclinical, neonatal animal studies in normal and surfactant-depleted lungs have demonstrated the feasibility of this technique to directly control the VThf in the normal compliance and low compliance situations. Different I:E ratios also can modify the effect of CO2 washout during HFOV combined with VG in a different way as without the VG modality. Finally, clinical use of this technique in newborn infants has demonstrated the possibility of using very high frequency combined with constant very low VThf to decrease the risk of lung trauma related to the ventilator.

Heliox does not affect gas exchange during high-frequency oscillatory ventilation if tidal volume is held constant

2003 ◽  
Vol 31 (7) ◽  
pp. 2006-2009 ◽  
Author(s):  
Andrew L. Katz ◽  
Michael A. Gentile ◽  
Damian M. Craig ◽  
George Quick ◽  
Ira M. Cheifetz
Keyword(s):  
Gas Exchange ◽  
Tidal Volume ◽  
High Frequency ◽  
High Frequency Oscillatory Ventilation ◽  
Oscillatory Ventilation ◽  
High Frequency Oscillatory

Four methods of measuring tidal volume during high-frequency oscillatory ventilation

2006 ◽  
Vol 34 (3) ◽  
pp. 751-757 ◽  
Author(s):  
David N. Hager ◽  
Mathew Fuld ◽  
David W. Kaczka ◽  
Henry E. Fessler ◽  
Roy G. Brower ◽  
...  
Keyword(s):  
Tidal Volume ◽  
High Frequency ◽  
High Frequency Oscillatory Ventilation ◽  
Oscillatory Ventilation ◽  
High Frequency Oscillatory
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