T Lymphocyte Subpopulations and Interleukin-2, Interferon-γ, and Interleukin-4 in Rat Pulpitis Experimentally Induced by Specific Bacteria

2002 ◽  
Vol 28 (3) ◽  
pp. 202-205 ◽  
Author(s):  
S KIM ◽  
S LIM
1984 ◽  
Vol 2 (1) ◽  
pp. 26-32 ◽  
Author(s):  
Robert L. Modlin ◽  
David A. Horwitz ◽  
Robert R. Jordan ◽  
John F. Gebhard ◽  
Clive R. Taylor ◽  
...  

1998 ◽  
Vol 4 (3) ◽  
pp. 193-197 ◽  
Author(s):  
Jan Debruyne ◽  
Jan Philippé ◽  
Jacques Dereuck ◽  
Annick Willems ◽  
Geert Leroux-Roels

In vitro tumor necrosis factor-a (TNF-a), interferon-g (IFN-g) and interleukin-2 (IL-2) production, serum neopterin levels, and T-lymphocyte subpopulations were determined on a monthly basis in 22 MS patients. We found increased in vitro TNF-a production from 4 weeks on prior to the day of an exacerbation. There was a significant correlation with in vitro IFN-g release, the absolute blood monocyte count and the serum neopterin levels, suggesting that monocytes stimulated by IFN-g play an important role in the TNF-a production. Serial analysis of in vitro TNF-a production proved to be a helpful tool in predicting relapses in MS patients. Furthermore, elevated levels of IFN-g and IL-2 after stimulation with OKT3 during exacerbations were demonstrated. These increases were not reflected by changes in T-lymphocyte subpopulations. However, significant differences in T-cell subsets were observed between controls and relapsing progressive patients.


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