Histamine Receptor Antagonism of Intolerance to Alcohol in the Oriental Population

1987 ◽  
Vol 175 (11) ◽  
pp. 661-667 ◽  
Author(s):  
NORMAN S. MILLER ◽  
DONALD W. GOODWIN ◽  
FOWLER C. JONES ◽  
MANUEL P. PARDO ◽  
MAN M. ANAND ◽  
...  
Keyword(s):  
Histamine Receptor ◽  
Receptor Antagonism ◽  
Oriental Population

Effect of Histamine‐Receptor Antagonism on the Acute Inflammatory Response to Aerobic Cycling Exercise

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Joshua Mangum ◽  
Karen Needham ◽  
Dylan Sieck ◽  
Christopher Minson ◽  
John Halliwill
Keyword(s):  
Inflammatory Response ◽  
Histamine Receptor ◽  
Acute Inflammatory Response ◽  
Cycling Exercise ◽  
Receptor Antagonism

Characterization of the histamine receptors in rabbit left atria

1981 ◽  
Vol 59 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Alicia Polanin ◽  
John H. McNeill
Keyword(s):  
Left Atrial ◽  
Histamine Receptor ◽  
Histamine Receptors ◽  
Receptor Blockade ◽  
Inotropic Response ◽  
Receptor Stimulation ◽  
Inotropic Effects ◽  
Receptor Antagonism ◽  
Positive Inotropic Effects

The effects of selective histamine receptor analogs were studied in electrically paced rabbit left atria. Atrial tension was increased by histamine (an H1 and H2 agonist), 4-methylhistamine and impromidine (H2 agonists), and 2-pyridylethylamine (PEA) (an H1 agonist). The responses to histamine and impromidine were not altered by propranolol (1 × 10−7 M) or reserpine pretreatment. However, the responses to 4-methylhistamine and PEA were significantly decreased upon pretreatment with propranolol or reserpine. Promethazine pretreatment (H1 receptor blockade) antagonized the inotropic effects of histamine and PEA but had no effect on the responses to 4-methylhistamine or impromidine. Cimetidine pretreatment (H2 receptor antagonism) competitively blocked the positive inotropic effects of histamine, 4-methylhistamine, and impromidine. These results suggest that the left atrial inotropic response is mediated through H1 and H2 receptor stimulation.

scholarly journals Effect of histamine-receptor antagonism on leg blood flow during exercise

2020 ◽  
Vol 128 (6) ◽  
pp. 1626-1634
Author(s):  
Matthew R. Ely ◽  
Stephen M. Ratchford ◽  
D. Taylor La Salle ◽  
Joel D. Trinity ◽  
D. Walter Wray ◽  
...  
Keyword(s):  
Blood Flow ◽  
Immune Responses ◽  
Histamine Receptor ◽  
Peak Capacity ◽  
Elevated Blood ◽  
Receptor Antagonism ◽  
Leg Blood Flow ◽  
Exercise Response ◽  
Exercise Induced

Leg blood flow during exercise was increased by taking antihistamines, which block the receptors for histamine, a molecule often associated with inflammatory and immune responses. The elevated blood flow occurred over exercise intensities ranging from 20 to 80% of peak capacity and during exercise of 60-min duration. These results suggest that exercise-induced elevations in histamine concentrations are involved in novel, poorly understood, and perhaps complex ways in the exercise response.

scholarly journals Effect of Histamine‐receptor Antagonism on VO 2Peak Improvements to Exercise Training

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Dylan Charles Sieck ◽  
Joshua E. Mangum ◽  
Matthew R. Ely ◽  
Mike E. Francisco ◽  
Emily A. Larson ◽  
...  
Keyword(s):  
Exercise Training ◽  
Histamine Receptor ◽  
Receptor Antagonism
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