LEFT VENTRICULAR DIASTOLIC FUNCTION AND AEROBIC POWER AFTER EXERCISE TRAINING AND CALCIUM CHANNEL BLOCKADE 1023

1996 ◽  
Vol 28 (Supplement) ◽  
pp. 172
Author(s):  
R. J. Petrella ◽  
D. A. Cunningham ◽  
D. H. Paterson
1997 ◽  
Vol 22 (1) ◽  
pp. 37-47 ◽  
Author(s):  
Robert J. Petrella ◽  
Donald A. Cunningham ◽  
David H. Paterson

We evaluated the effects of short-term, high-intensity exercise training and detraining on resting left ventricular diastolic function (LVDF) and maximal aerobic power (VO2max) in 7 sedentary older (age = 68 ± 4 years) men (n = 5) and women (n = 2). Training consisted of cycling for 60 min with power output set at 70% (Day 1), 80% (Day 2), and 90% (Days 3-5) of the pretraining peak work rate. Detraining consisted of a return to regular exercise habits. LVDF increased 10% in the early (E) flow velocity, decreased 18% in the late (A) flow velocity wave, and decreased 31% in the isovolumic relaxation time. VO2max was increased 12% while plasma volume (PV) increased 10% following, training and returned to baseline after detraining. The exercise-induced change in VO2max was directly related to the change in E/A (r =.52) and indirectly related to the change in IVRT (r = −.62). It was concluded that short-term, high-intensity exercise training improves LVDF and is tolerated well in older subjects, and that the calculated changes in PV and aerobic power are similar to those observed previously in a younger population. Key words: aging, training, cardiac filling


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