Crystalline Lens Thickness Changes as Observed by Pachometry

Purpose To investigate changes of crystalline lens position during accommodation in children with emmetropia, myopia, and hyperopia. Methods A total of 188 children (372 eyes) from 4 to 19 years old (mean age 11.3±4.43) with cycloplegic refractive error within a range +9.00 D to −9.00 D were enrolled. After a general ophthalmic examination, ultrasound biometry was performed, with the eye at a maximal accommodative effort. Cycloplegia was induced by triple installation of 1% tropicamide drops and 30 minutes later the biometric examination was repeated. Results In emmetropic eyes in the process of accommodation, the anterior pole of the crystalline lens moved forward by 0.144±0.14 mm (p ≤ 0.001); the position of the posterior pole did not change. In myopic eyes, the anterior pole moved forward by 0.071±0.13 mm (p≤0.001) and the posterior pole moved backward by 0.039±0.10 mm (p=0.003). In hyperopic eyes, the whole lens translocated anteriorly: anterior pole moved forward by 0.242±0.16 mm (p≤ 0.001) and posterior pole moved forward by 0.036±0.09 mm (p≤0.001). Differences among emmetropia, myopia, and hyperopia were statistically significant. Forward movement of the posterior pole correlated with a low axial length of the eye, and also with plus refractive error and with a smaller accommodative increase of lens thickness. Conclusions In children, accommodative changes of the crystalline lens position depend on refractive status.

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Repeatability and reproducibility of axial length, anterior chamber depth and crystalline lens thickness measurements using the Nidek US-500 Echoscan

African Vision and Eye Health ◽

10.4102/aveh.v74i1.16 ◽

2015 ◽

Vol 74 (1) ◽

Author(s):

Khathutshelo P. Mashige

Keyword(s):

Anterior Chamber ◽

Axial Length ◽

Repeated Measures ◽

Anterior Chamber Depth ◽

Correlation Coefficients ◽

Crystalline Lens ◽

Angle Closure ◽

Lens Thickness ◽

Primary Angle Closure Glaucoma ◽

The Right

Aim: The reliability of an instrument used to collect data for clinical and research purposes is greatly important, especially when it is used to determine changes in measured ocular parameters over time. The purpose of this study was to determine the intra-session repeatability and inter-session reproducibility of axial length (AL), anterior chamber depth (ACD) and crystalline lens thickness (LT) measurements using the Nidek US-500 Echoscan.Method: Fifty successive automatic measurements of the above parameters were taken on the right eyes only of 12 healthy subjects aged 23–44 years old, followed by similar repeated measures after 1 week. Sample standard deviations (s.d.), precision (P) and coefficient of repeatability (COR) were calculated to determine intra-session repeatability. Coefficient of reproducibility (CRP), Bland and Altman plots, concordance correlation coefficients (CCC) and paired t-tests that compared measurements obtained in the first and second sessions, were used to determine inter-session reproducibility.Results: Both the intra-session repeatability and inter-session reproducibility were within acceptable limits for the three variables assessed.Conclusion: The study showed that the Nidek US-500 Echoscan provides accurate, repeatable and reproducible measurements of AL, ACD and LT in healthy eyes. This finding will be of interest to optometrists and ophthalmologists who measure these parameters when diagnosing, managing and investigating conditions such as primary angle-closure glaucoma and keratoconus.

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Validation of Optical Coherence Tomography–Based Crystalline Lens Thickness Measurements in Children

Optometry and Vision Science ◽

10.1097/opx.0b013e318198198d ◽

2009 ◽

Vol 86 (3) ◽

pp. 181-187 ◽

Cited By ~ 16

Author(s):

Bret M. Lehman ◽

David A. Berntsen ◽

Melissa D. Bailey ◽

Karla Zadnik

Keyword(s):

Optical Coherence Tomography ◽

Crystalline Lens ◽

Optical Coherence ◽

Lens Thickness ◽

Thickness Measurements

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Increased crystalline lens thickness and phacomorphic glaucoma in patients with Fanconi anemia

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2006.04.036 ◽

2006 ◽

Vol 32 (10) ◽

pp. 1771-1774 ◽

Cited By ~ 6

Author(s):

Mostafa A. Elgohary ◽

Sheng K. Lim ◽

Dilani Siriwardena ◽

Anthony T. Moore ◽

Richard P. Wormald

Keyword(s):

Fanconi Anemia ◽

Crystalline Lens ◽

Lens Thickness

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Relationship between Crystalline Lens Thickness and Shape and the Identification of Anterior Ocular Segment Parameters for Predicting the Intraocular Lens Position after Cataract Surgery

BioMed Research International ◽

10.1155/2019/3458548 ◽

2019 ◽

Vol 2019 ◽

pp. 1-9 ◽

Cited By ~ 3

Author(s):

Tsukasa Satou ◽

Kimiya Shimizu ◽

Shuntaro Tsunehiro ◽

Akihito Igarashi ◽

Sayaka Kato ◽

...

Keyword(s):

Cataract Surgery ◽

Intraocular Lens ◽

Prediction Error ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Crystalline Lens ◽

Lens Thickness ◽

Lens Position ◽

The Difference ◽

Segment Data

Purpose. This study was performed to investigate the relationships among crystalline lens shape, actual intraocular lens (IOL) position, and crystalline lens thickness (LT), as measured by anterior segment optical coherence tomography (AS-OCT), and to determine anterior ocular segment parameters that predict postoperative IOL position. Methods. Seventy-nine eyes of 79 patients who underwent uneventful cataract surgery were enrolled. For crystalline lens preoperative anterior segment data, the LT, and anterior, equatorial, and posterior surface depths (ASD, ESD, and PSD, respectively) of crystalline lenses were quantitatively determined. For postoperative anterior segment data, the actual IOL position was quantified. Moreover, the following correlations were analyzed: LT with the ASD, ESD, PSD, and IOL position; IOL position with the ASD, ESD, and PSD; and refractive prediction error with the difference between the predicted postoperative anterior chamber depth (ACD) of the SRK/T formula and the IOL position, ASD, ESD, and PSD (each depth minus the predicted postoperative ACD of the SRK/T formula). Results. The LT was significantly correlated with the ASD (r = -0.65) and PSD (r = 0.41), whereas it was not correlated with the ESD or IOL position. The IOL position was significantly correlated with the ASD (r = 0.67), ESD (r = 0.72), and PSD (r = 0.74). The refractive prediction error was significantly correlated with the difference between the predicted postoperative ACD of the SRK/T formula and the IOL position (r = 0.65), ASD (r = 0.46), ESD (r = 0.54), and PSD (r = 0.58). Conclusions. The ESD and PSD obtained using AS-OCT were highly correlated with the IOL position and significantly correlated with the refractive prediction error. These findings suggest that the ESD and PSD may enhance the accuracy of actual IOL position prediction.

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A Simple Description of Age-Related Changes in Crystalline Lens Thickness

European Journal of Ophthalmology ◽

10.5301/ejo.2011.6253 ◽

2011 ◽

Vol 21 (5) ◽

pp. 597-603 ◽

Cited By ~ 2

Author(s):

Mari Carmen García-Domene ◽

Ma Amparo Díez-Ajenjo ◽

Víctor Gracia ◽

Adelina Felipe ◽

José M. Artigas

Keyword(s):

Crystalline Lens ◽

Simple Description ◽

Lens Thickness ◽

Age Related ◽

Age Related Changes

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Crystalline lens thickness determines the perceived chromatic difference in magnification

Journal of the Optical Society of America A ◽

10.1364/josaa.31.000524 ◽

2014 ◽

Vol 31 (3) ◽

pp. 524 ◽

Cited By ~ 2

Author(s):

Yun Chen ◽

Frank Schaeffel

Keyword(s):

Crystalline Lens ◽

Lens Thickness

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Analysis of Ocular Biometric Parameters in Patients with Cystoid Macular Edema

The Eye ◽

10.33791/2222-4408-2021-4-7-11 ◽

2021 ◽

Vol 23 (4) ◽

pp. 7-11

Author(s):

N. Yu. Gorbunova ◽

A. A. Voskresenskaya ◽

R. A. Yakovlev ◽

N. A. Pozdeeva

Keyword(s):

Cataract Surgery ◽

Macular Edema ◽

Axial Length ◽

Crystalline Lens ◽

Thickness Measurement ◽

Federal State ◽

Foveal Thickness ◽

Biometric Parameters ◽

Lens Thickness ◽

Post Surgery

Relevance. Cataract surgeries are among the most frequently performed ophthalmic surgeries in the world. Despite the fact that they become less traumatic every year, such interventions are still accompanied by post-surgery complications, one of which is cystic macular edema (CME) or Irwin–Gass syndrome. Purpose. To analyze ocular biometric parameters in patients with CME. Material and Methods. The study included 40 patients (40 eyes) with post-surgery CME. All patients underwent ultrasound biometry, axial length measurement, crystalline lens thickness measurement with Bio&Pachy Meter AL-4000 (Tomey, Japan) and optical coherence tomography (OCT) with Cirrus HD-OCT 5000 (Carl Zeiss, Germany) to assess central foveal thickness. Depending on the axial length, all eyes were divided into “long” and “short” relative to the average axial length of 23.3 mm. The data was analyzed with STATISTICA 10 software (StatSoft Inc., USA). Results. The incidence of CME after uncomplicated cataract surgery in Cheboksary branch of the S. Fyodorov Eye Microsurgery Federal State Institution amounted to 0.002%. Axial length among patients with CME ranged from 20.53 mm to 25.4 mm; the average value amounted to 22.67 ± 1.05 mm. The majority of eyes were “short” – 31 eyes (77.5%), whereas 9 eyes (22.5%) were “long”. “Short” eyes exhibited a greater crystalline lens thickness (4.81 ± 0.53 mm) compared to “long” eyes (4.42 ± 0.42 mm) (рM-U = 0.014). Conclusion. The development of CME after uncomplicated cataract surgery is more often observed in eyes with axial length smaller than 23.3 mm.

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