Serum levels of cardiac troponin I and troponin T in estimating myocardial infarct size soon after reperfusion

1997 ◽  
Vol 8 (7) ◽  
pp. 433-440 ◽  
Author(s):  
Hiromitsu Tanaka ◽  
Satoshi Abe ◽  
Tsuminori Yamashita ◽  
Shinichi Arima ◽  
Masahiko Saigo ◽  
...  
Keyword(s):  
Infarct Size ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Myocardial Infarct ◽  
Serum Levels ◽  
Cardiac Troponin I ◽  
Myocardial Infarct Size

scholarly journals Potential Use of Quercetin as Protective Agent against Hydroxychloroquine Induced Cardiotoxicity

2021 ◽  
Vol 2 (3) ◽  
pp. 185-192
Author(s):  
Mona G Amer ◽  
Nader M Mohamed
Keyword(s):  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Serum Levels ◽  
Treated Group ◽  
Cardiac Troponin I ◽  
Male Rats ◽  
Total Serum ◽  
Protective Agent ◽  
Prophylactic Measure

The aim of this study is to investigate the protective effects of Quercetin (QCT) on Hydroxychloquine (HCQ)-induced myocardial affection in rats. HCQ has been found to produce toxic effects including cardiac manifestation. Adding QCT to HCQ ameliorates its effects and prevents cardiac manifestations. For this purpose, eighty adult male rats were divided into four groups (n = 20). Group 1 (control) and group 2 (QCT-treated). Group 3 (HCQ treated) received 20 mg/kg of HCQ and group 4 (QCT + HCQ treated) received quercetin (50 mg/kg; orally) combined with HCQ for 4 weeks. Cardiac troponin-I and oxidative markers (Malondialdehyde (MDA), and total serum antioxidant) were estimated in serum. In addition, histopathological and morphometric changes of the rat heart were assessed. The HCQ treated group showed increased serum levels of cardiac troponin-I, MDA and decreased serum levels of total antioxidant. Pathological picture of myocardial hypertrophy and degeneration together with depleted cardiac tissue expression of troponin T were also observed. The characteristic features were presence of whorled myelin bodies and curvilinear bodies by EM examination. These parameters improved better in the group receiving combination of QCT together with HCQ. So, Adding QCT to HCQ could be prophylactic measure against its cardiotoxic effect compared with HCQ treatment alone.

Cardiac Troponin T Levels at 96 Hours Reflect Myocardial Infarct Size: A Pathoanatomical Study

Cardiology ◽  
2000 ◽  
Vol 93 (4) ◽  
pp. 249-253 ◽  
Author(s):  
Andrew Remppis ◽  
Philipp Ehlermann ◽  
Evangelos Giannitsis ◽  
Tobias Greten ◽  
Patrick Most ◽  
...  
Keyword(s):  
Infarct Size ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Myocardial Infarct ◽  
Cardiac Troponin T ◽  
Myocardial Infarct Size

scholarly journals Clinical Evaluation of the ACS:180 Cardiac Troponin I Assay

2001 ◽  
Vol 38 (5) ◽  
pp. 509-519 ◽  
Author(s):  
Paul O Collinson ◽  
Nigel Wiggins ◽  
David C Gaze
Keyword(s):  
Endurance Training ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Training Group ◽  
Storage Conditions ◽  
Cardiac Troponin I ◽  
Admission Diagnosis ◽  
Coronary Syndromes ◽  
Analytical Imprecision

All patients admitted to the coronary care unit with suspected acute coronary syndromes were evaluated by serial electrocardiography and blood draws on admission and at 4 and 12h from admission. Diagnosis was based on conventional WHO criteria. Samples were measured for creatine kinase (CK), cardiac troponin T (cTnT), myoglobin, CK isoenzyme MB (CK-MB) and cardiac troponin I (cTnI). A set of samples from individuals undergoing extreme endurance training was also examined. Analytical imprecision was consistent with published quality goals. Samples were stable for cTnI under a range of storage conditions, including multiple freeze-thaw cycles. CK-MB, cTnI and cTnT were equally efficient for the diagnosis of acute myocardial infarction, irrespective of the final diagnostic criteria used. Both cTnI and cTnT were of equal efficiency in the identification of a high-risk subgroup of patients with unstable angina. Significant elevations of cTnI were not seen in an endurance-training group.

Patterns and Diagnostic Value of Cardiac Troponin I vs. Troponin T and CKMB after OPCAB Surgery*

2001 ◽  
Vol 49 (3) ◽  
pp. 137-143 ◽  
Author(s):  
A. A. Peivandi ◽  
M. Dahm ◽  
U. Hake ◽  
G. Hafner ◽  
U. T. Opfermann ◽  
...  
Keyword(s):  
Cardiac Troponin ◽  
Troponin I ◽  
Troponin T ◽  
Diagnostic Value ◽  
Cardiac Troponin I ◽  
Opcab Surgery
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