Morphological Changes in Primate Aqueous Humor Formation and Drainage Tissues After Long-Term Treatment with Antiglaucomatous Drugs

1993 ◽  
Vol 2 (4) ◽  
pp. 316???328
Author(s):  
Elke L??tjen-Drecoll ◽  
Paul L. Kaufman
Keyword(s):  
Aqueous Humor ◽  
Morphological Changes ◽  
Term Treatment ◽  
Long Term Treatment

scholarly journals TOXICITY STUDIES OF A DEVELOPED NEPHROPROTECTIVE POLYHERBAL FORMULATION IN EXPERIMENTAL RATS

2019 ◽  
pp. 166-169
Author(s):  
SASIKALA S ◽  
KANNIKAPARAMESWARI N
Keyword(s):  
Body Weight ◽  
Acute Toxicity ◽  
Morphological Changes ◽  
Hematological Parameters ◽  
Term Treatment ◽  
Behavioral Pattern ◽  
Polyherbal Formulation ◽  
Toxicity Studies ◽  
Long Term Treatment

Objective: In the present study, acute toxicity studies were evaluated on scientifically developed nephroprotective polyherbal formulation. Polyherbal formulation consists of ethanolic extracts of dried plants of Boerhavia diffusa (BD) and Achyranthes aspera (AA). Materials and Methods: In an acute toxicity study, polyherbal formulation was administered once orally at doses ranging from 250 mg/kg to 2000 mg/kg for 15 days. Body weight and food consumption were noted during the study period. Behavioral pattern and toxic effects were monitored in each group of animals daily. At the end of the study, blood was withdrawn for hematology and biochemical estimations. The animals were then sacrificed, and the liver, kidney, heart, and brain were dissected out which were observed for any gross morphological changes. The weights of organs were also noted. Results: The results showed no changes in body weight, organ weight, food intake, hematological parameters, and liver function test when compared with control. The organs did not show any evidence of gross morphological changes. Conclusion: It is concluded that developed polyherbal formulation, at a dose of 2000 mg/kg, is safe for long-term treatment of kidney disorders

MORPHOLOGICAL CHANGES IN RAT PANCREATIC ACINAR CELLS INDUCED BY LONG-TERM TREATMENT WITH CYCLOSPORINE AND THEIR REVERSAL AFTER WITHDRAWAL

1990 ◽  
Vol 50 (5) ◽  
pp. 830-833 ◽  
Author(s):  
DANIELE BANI ◽  
FRANCO FILIPPONI ◽  
LEONARDO MAGNANI ◽  
DIDIER HOUSSIN ◽  
PAOLO ROMAGNOLI
Keyword(s):  
Morphological Changes ◽  
Acinar Cells ◽  
Term Treatment ◽  
Pancreatic Acinar Cells ◽  
Long Term Treatment

Hypnotherapy is effective in the long-term treatment of functional dyspepsia

2001 ◽  
Vol 120 (5) ◽  
pp. A115-A115 ◽  
Author(s):  
E CALVERT ◽  
L HOUGHTON ◽  
P COOPER ◽  
P WHORWELL
Keyword(s):  
Functional Dyspepsia ◽  
Term Treatment ◽  
Long Term Treatment

1608: Long-Term Treatment with High Doses of Sildenafil Does Not Up-Regulate the Levels of Phosphodiesterase 5 (Pde5) in the Rat Penis

2004 ◽  
Vol 171 (4S) ◽  
pp. 424-424 ◽  
Author(s):  
Monica G. Ferrini ◽  
Eliane G. Valente ◽  
Jacob Rajfer ◽  
Nestor F. Gonzalez-Cadavid
Keyword(s):  
Term Treatment ◽  
Long Term Treatment ◽  
High Doses ◽  
Phosphodiesterase 5

Long-Term Treatment Outcomes for Heroin Dependence: The 11-Year Follow-Up of the ATOS Study

2013 ◽  
Author(s):  
Christina Marel ◽  
Maree Teesson ◽  
Shane Darke ◽  
Katherine Mills ◽  
Joanne Ross ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Term Treatment ◽  
Heroin Dependence ◽  
Long Term Treatment
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