Fatty acid-binding protein as a serum marker for the early diagnosis of acute coronary syndrome

2005 ◽  
Vol 12 (4) ◽  
pp. 206
Author(s):  
Alonso-Valle Hector ◽  
Garc??a-Castrillo Luis Gerardo
Keyword(s):  
Acute Coronary Syndrome ◽  
Fatty Acid ◽  
Early Diagnosis ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Serum Marker ◽  
Fatty Acid Binding ◽  
Coronary Syndrome ◽  
Acid Binding Protein

Clinical assessment of heart-type fatty acid binding protein in early diagnosis of acute coronary syndrome

2008 ◽  
Vol 15 (3) ◽  
pp. 140-144 ◽  
Author(s):  
Hector Alonso Valle ◽  
Luis García-Castrillo Riesgo ◽  
Miguel Sántalo Bel ◽  
Francisco Epelde Gonzalo ◽  
Miguel Sánchez Sanchez ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Fatty Acid ◽  
Early Diagnosis ◽  
Clinical Assessment ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Coronary Syndrome ◽  
Acid Binding Protein

scholarly journals Elevated Heart-Type Fatty Acid-Binding Protein Predicts Early Myocardial Injury and Aids in the Diagnosis of Non-St Elevation Myocardial Infarction

2009 ◽  
Vol 16 (3) ◽  
pp. 141-147 ◽  
Author(s):  
GY Naroo ◽  
S Mohamed Ali ◽  
V Butros ◽  
A Al Haj ◽  
I Mohammed ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Fatty Acid ◽  
Chest Pain ◽  
Fatty Acid Binding Protein ◽  
Troponin T ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Coronary Syndrome ◽  
Acid Binding Protein

Background Biomarkers play an important role in the early diagnosis, risk stratification and management of patients with the acute coronary syndrome. Objective The objective of this study was to evaluate the clinical reliability of heart-type fatty acid-binding protein (h-FABP) in identifying patients with the acute coronary syndrome in the early hours of chest pain. Methods Creatine kinase (CK-MB) (in laboratory), troponin T (in laboratory) and h-FABP (with point-of-care test CardioDetect®) were performed on 791 patients who presented with chest pain with duration since onset ranging from 20 minutes to 12 hours. Results Data of the 791 patients were analysed. h-FABP had a higher sensitivity of 75.76% and a specificity of 96.97% compared with 58.59% and 98.84% for troponin T and 68.69% and 97.54% for CK-MB respectively (in the first 6 hours). Conclusion: h-FABP was found to be a better biomarker of cardiac necrosis in the early hours in the diagnosis of non-conclusive ECG in patients with acute myocardial infarction. (Hong Kong j.emerg.med. 2009;16:141–147)

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