Nuclear Medicine Imaging System Safety Alert Prompted by Accident

1997 ◽  
Vol 27 (4) ◽  
pp. 25-27
Keyword(s):  
Nuclear Medicine ◽  
Imaging System ◽  
Nuclear Medicine Imaging ◽  
System Safety ◽  
Safety Alert

scholarly journals Correction for the Partial Volume Effects (PVE) in Nuclear Medicine Imaging: A Post-Reconstruction Analytic Method

2021 ◽  
Vol 11 (14) ◽  
pp. 6460
Author(s):  
Fabio Di Martino ◽  
Patrizio Barca ◽  
Eleonora Bortoli ◽  
Alessia Giuliano ◽  
Duccio Volterrani
Keyword(s):  
Nuclear Medicine ◽  
Imaging System ◽  
Tomographic Reconstruction ◽  
Mathematical Expression ◽  
Reconstruction Algorithm ◽  
Volume Effect ◽  
Nuclear Medicine Imaging ◽  
Theoretical Derivation ◽  
Reconstruction Process ◽  
Partial Volume

Quantitative analyses in nuclear medicine are increasingly used, both for diagnostic and therapeutic purposes. The Partial Volume Effect (PVE) is the most important factor of loss of quantification in Nuclear Medicine, especially for evaluation in Region of Interest (ROI) smaller than the Full Width at Half Maximum (FWHM) of the PSF. The aim of this work is to present a new approach for the correction of PVE, using a post-reconstruction process starting from a mathematical expression, which only requires the knowledge of the FWHM of the final PSF of the imaging system used. After the presentation of the theoretical derivation, the experimental evaluation of this method is performed using a PET/CT hybrid system and acquiring the IEC NEMA phantom with six spherical “hot” ROIs (with diameters of 10, 13, 17, 22, 28, and 37 mm) and a homogeneous “colder” background. In order to evaluate the recovery of quantitative data, the effect of statistical noise (different acquisition times), tomographic reconstruction algorithm with and without time-of-flight (TOF) and different signal-to-background activity concentration ratio (3:1 and 10:1) was studied. The application of the corrective method allows recovering the loss of quantification due to PVE for all sizes of spheres acquired, with a final accuracy less than 17%, for lesion dimensions larger than two FWHM and for acquisition times equal to or greater than two minutes.

Modular 64×64 CdZnTe Arrays With Multiplexer Readout for High-Resolution Nuclear Medicine Imaging

1997 ◽  
Vol 487 ◽  
Author(s):  
J. M. Woolfenden ◽  
H. B. Barber ◽  
H. H. Barrett ◽  
E. L. Dereniak ◽  
J. D. Eskin ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
High Resolution ◽  
Spatial Resolution ◽  
Personal Computer ◽  
Imaging System ◽  
Radiation Detectors ◽  
Readout Circuit ◽  
Nuclear Medicine Imaging ◽  
Pixel Pitch

AbstractWe are developing modular arrays of CdZnTe radiation detectors for high-resolution nuclear medicine imaging. Each detector is delineated into a 64×64 array of pixels; the pixel pitch is 380 jim. Each pixel is connected to a corresponding pad on a multiplexer readout circuit. The imaging system is controlled by a personal computer. We obtained images of standard nuclear medicine phantoms in which the spatial resolution of approximately 1.5 mm was limited by the collimator that was used. Significant improvements in spatial resolution should be possible with different collimator designs. These results are promising for high-resolution nuclear medicine imaging.

Modular 64×64 CdZnTe Arrays With Multiplexer Readout for High-Resolution Nuclear Medicine Imaging

1997 ◽  
Vol 484 ◽  
Author(s):  
J. M. Woolfenden ◽  
H. B. Barber ◽  
H. H. Barrett ◽  
E. L. Dereniak ◽  
J. D. Eskin ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
High Resolution ◽  
Spatial Resolution ◽  
Personal Computer ◽  
Imaging System ◽  
Radiation Detectors ◽  
Readout Circuit ◽  
Nuclear Medicine Imaging ◽  
Pixel Pitch

AbstractWe are developing modular arrays of CdZnTe radiation detectors for high-resolution nuclear medicine imaging. Each detector is delineated into a 64×64 array of pixels; the pixel pitch is 380 ptm. Each pixel is connected to a corresponding pad on a multiplexer readout circuit. The imaging system is controlled by a personal computer. We obtained images of standard nuclear medicine phantoms in which the spatial resolution of approximately 1.5 mm was limited by the collimator that was used. Significant improvements in spatial resolution should be possible with different collimator designs. These results are promising for high-resolution nuclear medicine imaging.

Patients with fever of unknown origin (FUO): diagnosis by nuclear medicine imaging

2001 ◽  
Vol 40 (03) ◽  
pp. 59-70 ◽  
Author(s):  
W. Becker ◽  
J. Meiler
Keyword(s):  
Nuclear Medicine ◽  
Fever Of Unknown Origin ◽  
Tumor Imaging ◽  
White Blood Cells ◽  
Unknown Origin ◽  
Final Diagnosis ◽  
Recurrent Fever ◽  
Nuclear Medicine Imaging

SummaryFever of unknown origin (FUO) in immunocompetent and non neutropenic patients is defined as recurrent fever of 38,3° C or greater, lasting 2-3 weeks or longer, and undiagnosed after 1 week of appropriate evaluation. The underlying diseases of FUO are numerous and infection accounts for only 20-40% of them. The majority of FUO-patients have autoimmunity and collagen vascular disease and neoplasm, which are responsible for about 50-60% of all cases. In this respect FOU in its classical definition is clearly separated from postoperative and neutropenic fever where inflammation and infection are more common. Although methods that use in-vitro or in-vivo labeled white blood cells (WBCs) have a high diagnostic accuracy in the detection and exclusion of granulocytic pathology, they are only of limited value in FUO-patients in establishing the final diagnosis due to the low prevalence of purulent processes in this collective. WBCs are more suited in evaluation of the focus in occult sepsis. Ga-67 citrate is the only commercially available gamma emitter which images acute, chronic, granulomatous and autoimmune inflammation and also various malignant diseases. Therefore Ga-67 citrate is currently considered to be the tracer of choice in the diagnostic work-up of FUO. The number of Ga-67-scans contributing to the final diagnosis was found to be higher outside Germany than it has been reported for labeled WBCs. F-l 8-2’-deoxy-2-fluoro-D-glucose (FDG) has been used extensively for tumor imaging with PET. Inflammatory processes accumulate the tracer by similar mechanisms. First results of FDG imaging demonstrated, that FDG may be superior to other nuclear medicine imaging modalities which may be explained by the preferable tracer kinetics of the small F-l 8-FDG molecule and by a better spatial resolution of coincidence imaging in comparison to a conventional gamma camera.

scholarly journals 73.1: Large-Area Plasma-Panel Radiation Detectors for Nuclear Medicine Imaging to Homeland Security and the Super Large Hadron Collider

2010 ◽  
Vol 41 (1) ◽  
pp. 1080 ◽  
Author(s):  
Peter S. Friedman ◽  
Robert Ball ◽  
J. Wehrley Chapman ◽  
Daniel S. Levin ◽  
Curtis Weaverdyck ◽  
...  
Keyword(s):  
Nuclear Medicine ◽  
Large Hadron Collider ◽  
Homeland Security ◽  
Hadron Collider ◽  
Radiation Detectors ◽  
Nuclear Medicine Imaging ◽  
Large Area

Nuclear medicine imaging procedures in differentiated thyroid carcinoma patients with negative iodine scan

2000 ◽  
Vol 54 (6) ◽  
pp. 337-344 ◽  
Author(s):  
D. Rubello ◽  
G. Saladini ◽  
A. Carpi ◽  
D. Casara
Keyword(s):  
Nuclear Medicine ◽  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Imaging Procedures ◽  
Nuclear Medicine Imaging ◽  
Iodine Scan
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