Aortic pulse wave velocity as a predictor of the presence of CAD in subjects with suspected CAD; relation to the metabolic syndrome

2006 ◽  
Vol 13 (Supplement 1) ◽  
pp. S58
Author(s):  
AP Kotsia ◽  
KK Naka ◽  
C Bourantas ◽  
T Tzimas ◽  
MI Papafaklis ◽  
...  
2017 ◽  
Vol 23 (1) ◽  
Author(s):  
Dong-Hyeon Lee ◽  
Ho-Joong Youn ◽  
Woo-Baek Chung ◽  
Yun-Seok Choi ◽  
Jong-Min Lee ◽  
...  

2018 ◽  
Vol 43 (12) ◽  
pp. 1247-1256 ◽  
Author(s):  
Majid M. Syed-Abdul ◽  
Qiong Hu ◽  
Miriam Jacome-Sosa ◽  
Jaume Padilla ◽  
Camila Manrique-Acevedo ◽  
...  

Increased aortic stiffness, measured by carotid-to-femoral pulse wave velocity (PWV), is an independent predictor of cardiovascular disease, and past data have shown that low-fat and low-energy diets, fed for 8–24 weeks, lower PWV. The purpose of this study was to determine whether a reduction in PWV would be achieved by dietary carbohydrate (CHO) restriction, shown to bring about weight loss over a shorter timeframe. Men (n = 10, age: 41.8 ± 10.2 years, BMI: 34.2 ± 3.0 kg/m2 (mean ± SD)) and women (n = 10, age: 38.6 ± 6.1 years, BMI: 33.5 ± 3.8 kg/m2) with characteristics of insulin resistance and the metabolic syndrome consumed a structured, CHO-restricted diet for 4 weeks (energy deficit, 645 kcal/day). For the whole group, subjects lost 5.4% ± 0.5% (P < 0.001) of body weight and experienced significant reductions in blood pressure (6%–8%), plasma insulin (34%), and triglycerides (34%). PWV was reduced by 6% ± 2% (7.1 ± 0.2 m/s to 6.7 ± 0.2 m/s, P = 0.008) and surprisingly, in women, it fell significantly (from 7.2 ± 0.3 m/s to 6.3 ± 0.3 m/s, P = 0.028), while no changes were observed in men (7.2 ± 0.3 vs. 7.0 ± 0.3 m/s, P = 0.144). This is the first study to demonstrate that weight loss can improve PWV in as little as 4 weeks and that dietary CHO restriction may be an effective treatment for reducing aortic stiffness in women. Future studies are needed to establish the mechanisms by which dietary CHO restriction may confer more cardiovascular benefits to women than to men.


Pulse ◽  
2020 ◽  
Vol 8 (1-2) ◽  
pp. 31-39
Author(s):  
Ruchada Sri-amad ◽  
Nawiya Huipao ◽  
Piyapong Prasertsri ◽  
Thapanee Roengrit

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