SODIUM CONCENTRATION OF SWEAT CORRELATES WITH DIETARY SODIUM INTAKE

Positive sodium balance is necessary for normal somatic growth of the neonate, and the neonatal renal response to volume expansion (VE) is attenuated compared with the adult. To test the hypothesis that dietary sodium modulates the developmental response to VE, preweaned rats were artificially reared with either a normal (25 meq/l)- or high-sodium (145 meq/l) diet for 7-8 days and were compared with adult rats receiving normal or high sodium. Serum sodium concentration remained normal in adults on high sodium, whereas neonates became hypernatremic. Glomerular filtration rate (GFR), urinary flow (V), and urinary sodium (UNaV) were measured before and after acute saline VE (1% body wt). While remaining constant in preweaned rats, GFR increased > 50% in adult rats after VE (P < 0.05). High sodium intake augmented V and UNaV after VE but was not sustained in neonates as in adults. Plasma atrial natriuretic peptide (ANP) and guanosine 3',5'-cyclic monophosphate excretion (UcGMPV) were measured, and baseline UcGMPV was lower in preweaned rats receiving normal sodium but increased to levels similar to adult levels after VE. Postexpansion plasma ANP was higher in preweaned rats than in adult rats and was not affected by dietary sodium regardless of age. We conclude that the attenuated postexpansion natriuresis in the neonate is due in part to an adaptive response to limited sodium intake. However, neonatal compensation to increased sodium intake is incomplete and independent of plasma ANP.

Download Full-text

SHORT-TERM CHANGES IN DIETARY SODIUM INTAKE INFLUENCE SWEAT SODIUM CONCENTRATION AND MUSCLE SODIUM CONTENT IN HEALTHY SUBJECTS

Journal of Hypertension ◽

10.1097/01.hjh.0000570980.69246.d1 ◽

2019 ◽

Vol 37 ◽

pp. e62-e63 ◽

Cited By ~ 1

Author(s):

P. Braconnier ◽

B. Milani ◽

N. Loncle ◽

J.M. Lourenco ◽

W. Brito ◽

...

Keyword(s):

Healthy Subjects ◽

Sodium Intake ◽

Sodium Concentration ◽

Sodium Content ◽

Dietary Sodium ◽

Short Term ◽

Sweat Sodium Concentration ◽

Sweat Sodium

Download Full-text

Short-term changes in dietary sodium intake influence sweat sodium concentration and muscle sodium content in healthy individuals

Journal of Hypertension ◽

10.1097/hjh.0000000000002234 ◽

2020 ◽

Vol 38 (1) ◽

pp. 159-166 ◽

Cited By ~ 2

Author(s):

Philippe Braconnier ◽

Bastien Milani ◽

Nicolas Loncle ◽

Joao M. Lourenco ◽

Wendy Brito ◽

...

Keyword(s):

Sodium Intake ◽

Sodium Concentration ◽

Sodium Content ◽

Dietary Sodium ◽

Healthy Individuals ◽

Short Term ◽

Sweat Sodium Concentration ◽

Sweat Sodium

Download Full-text

Dietary Sodium Intake: A Determinant of Postprandial Plasma Sodium Concentration in the Dog

Clinical Science ◽

10.1042/cs0620471 ◽

1982 ◽

Vol 62 (5) ◽

pp. 471-477 ◽

Cited By ~ 1

Author(s):

E. G. Schneider ◽

Sarah D. Gleason ◽

A. Zucker

Keyword(s):

Sodium Excretion ◽

Sodium Intake ◽

Urinary Sodium Excretion ◽

Sodium Concentration ◽

Dietary Sodium ◽

Sodium Balance ◽

Plasma Sodium ◽

Free Access ◽

Potassium Excretion ◽

Plasma Sodium Concentration

1. The effect of dietary sodium intake on pre-and post-prandial plasma sodium concentrations and on the pattern of sodium and potassium excretion was determined in conscious female dogs, who were allowed free access to water and were fed on commercial low sodium diets supplemented with 0, 50, 100 or 250 mmol of sodium chloride/day for 6 days. 2. The preprandial plasma sodium concentration was not altered by the dietary sodium intake. However, the 4 h postprandial plasma sodium concentration was linearly related to the magnitude of dietary sodium intake, whereas the 8 h postprandial plasma sodium concentration was elevated only in dogs receiving 250 mmol of sodium/day. 3. The (0–8 h/0–24 h) ratio for urinary sodium excretion was significantly correlated with both the dietary sodium intake and the postprandial increase in plasma sodium concentration. 4. The 24 h excretion of potassium was not markedly affected by the dietary sodium intake; however, the (0–8 h/0–24 h) ratio for potassium excretion was significantly correlated with both the dietary sodium intake and the (0–8 h/0–24 h) ratio for sodium excretion. 5. These data indicate that: (a) postprandial increases in plasma sodium concentration need to be considered when evaluating the mechanisms involved in the daily regulation of sodium balance; (b) the daily pattern of potassium excretion is closely linked to the dietary sodium intake.

Download Full-text

What Is the Optimal Sodium Concentration in the Dialysate?

Kidney and Dialysis ◽

10.3390/kidneydial2010002 ◽

2021 ◽

Vol 2 (1) ◽

pp. 4-5

Author(s):

Salvador López-Gil ◽

Magdalena Madero

Keyword(s):

Lung Ultrasound ◽

Sodium Intake ◽

Dry Weight ◽

Sodium Concentration ◽

Dietary Sodium ◽

Volume Status ◽

Intradialytic Hypotension ◽

Close Monitoring ◽

Relative Blood Volume ◽

Dialysate Sodium

Based on our experience in our hemodiafiltration unit we would recommend a personalized isonatremic dialysate bath. We currently prescribe 137 meq (isonatremic) or delta dialysate Na/serum Na less than 2 meq. In addition to the sodium prescribed in the dialysate, for the majority of our patients we do not restrict dietary sodium or water intake. The average sodium intake is 2775 mg per day and blood pressure is maintained without hypertensive medications. We acknowledge that part of the success for achieving dry weight may not be attributable only to the dialysate sodium but is likely the result of a combination of multiple factors such as convection therapy, cooling of dialysate, close monitoring of volume status during sessions with relative blood volume, presence of a nephrologist during all sessions and assessing volume status regularly with lung ultrasound and bioimpedance. In our experience, exercising during hemodialysis has additionally been associated with better hemodynamic status and less intradialytic hypotension. Moreover, we acknowledge there is little evidence to support a gradient dialysate to serum sodium of less than 2 meq and that our approach may not be optimal.

Download Full-text

Effects of sodium fertilizers and supplements on milk production and mammary gland health

Journal of Dairy Research ◽

10.1017/s0022029999003970 ◽

2000 ◽

Vol 67 (1) ◽

pp. 1-12 ◽

Cited By ~ 8

Author(s):

CLIVE J. C. PHILLIPS ◽

PAUL C. CHIY ◽

DAVID R. ARNEY ◽

OLAV KÄRT

Keyword(s):

Milk Production ◽

Milk Yield ◽

Dry Matter ◽

Sodium Intake ◽

Sodium Concentration ◽

Sodium Content ◽

Dietary Sodium ◽

Milk Samples ◽

Series Of Experiments ◽

High Level

A series of experiments was conducted to investigate the effects of sodium fertilizers and supplements on the milk production and mammary health of dairy cows. In Expt 1, where sodium fertilizer was applied to productive pastures consisting mainly of the natrophile perennial rye-grass, the herbage sodium content and the milk yield of cows was increased and milk somatic cell count (SCC) reduced. In Expt 2, which used pastures containing less productive, natrophobic grasses and broad-leaved plants in Estonia, sodium fertilizer did not increase herbage sodium content and did not affect milk production or composition. In Expt 3 the sodium content of the diet of individually tethered cows was increased from 1 to either 6 or 11 g/kg dry matter (DM) by adding salt to their restricted feed allowance, and the cows' milk yield was increased by the high level of sodium supplement and milk SCC were reduced by both levels of sodium supplement. The calcium and magnesium status of cows was improved by the sodium supplement. In Expt 4 a low level of supplementary salt was included in the ration of tethered cows to increase the sodium content of the diet from 2 to 3·6 g/kg DM. No effects on milk yield or SCC were found, but the sodium supplement reduced Staphylococcus aureus contamination of the milk, but not the proportion of milk samples infected with Escherichia coli. It was concluded that the optimum dietary sodium concentration for maximum milk yield was greater than the published requirements, and that substantial increases in sodium intake above current requirements also reduced milk SCC.

Download Full-text