The First Trial of Phase Contrast Imaging for Digital Full-Field Mammography Using a Practical Molybdenum X-Ray Tube

A full-field hard X-ray imaging beamline (BL-4) was designed, developed, installed and commissioned recently at the Indus-2 synchrotron radiation source at RRCAT, Indore, India. The bending-magnet beamline is operated in monochromatic and white beam mode. A variety of imaging techniques are implemented such as high-resolution radiography, propagation- and analyzer-based phase contrast imaging, real-time imaging, absorption and phase contrast tomographyetc. First experiments on propagation-based phase contrast imaging and micro-tomography are reported.

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Towards tender X-rays with Zernike phase-contrast imaging of biological samples at 50 nm resolution

Journal of Synchrotron Radiation ◽

10.1107/s1600577514010388 ◽

2014 ◽

Vol 21 (4) ◽

pp. 790-794 ◽

Cited By ~ 10

Author(s):

Ismo Vartiainen ◽

Martin Warmer ◽

Dennis Goeries ◽

Eva Herker ◽

Rudolph Reimer ◽

...

Keyword(s):

Phase Contrast ◽

Three Dimensional ◽

Phase Contrast Imaging ◽

X Rays ◽

Contrast Imaging ◽

Full Field ◽

X Ray ◽

Lipid Droplet Formation ◽

Contrast Microscope ◽

Science Application

X-ray microscopy is a commonly used method especially in material science application, where the large penetration depth of X-rays is necessary for three-dimensional structural studies of thick specimens with high-Zelements. In this paper it is shown that full-field X-ray microscopy at 6.2 keV can be utilized for imaging of biological specimens with high resolution. A full-field Zernike phase-contrast microscope based on diffractive optics is used to study lipid droplet formation in hepatoma cells. It is shown that the contrast of the images is comparable with that of electron microscopy, and even better contrast at tender X-ray energies between 2.5 keV and 4 keV is expected.

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C22 Quantitative Sub-100nm Phase-Contrast Imaging Using an SEM-Based Full-Field X-ray Microscope—Invited

Powder Diffraction ◽

10.1154/1.1979019 ◽

2005 ◽

Vol 20 (2) ◽

pp. 173-173

Author(s):

S.W. Wilkins ◽

D. Gao ◽

T.E. Gureyev ◽

S.C. Mayo ◽

P.R. Miller ◽

...

Keyword(s):

Phase Contrast ◽

Phase Contrast Imaging ◽

Contrast Imaging ◽

Full Field ◽

X Ray

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Large-area full field x-ray differential phase-contrast imaging using 2D tiled gratings

Journal of Physics D Applied Physics ◽

10.1088/1361-6463/aa6e85 ◽

2017 ◽

Vol 50 (22) ◽

pp. 225401 ◽

Cited By ~ 12

Author(s):

Tobias J Schröter ◽

Frieder J Koch ◽

Danays Kunka ◽

Pascal Meyer ◽

Sabrina Tietze ◽

...

Keyword(s):

Phase Contrast ◽

Phase Contrast Imaging ◽

Contrast Imaging ◽

Large Area ◽

Full Field ◽

X Ray ◽

Differential Phase ◽

Differential Phase Contrast

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Commentary: Is X-ray Phase Contrast Imaging an Anatomical Klondike for Surgeons?

Seminars in Thoracic and Cardiovascular Surgery ◽

10.1053/j.semtcvs.2020.04.011 ◽

2020 ◽

Vol 32 (4) ◽

pp. 969-970

Author(s):

Sergio A. Carrillo

Keyword(s):

Phase Contrast ◽

Phase Contrast Imaging ◽

Contrast Imaging ◽

X Ray

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Image Quality Analysis of X-ray Grating Interferometer Using Integrating-bucket Method

Journal of Imaging Science and Technology ◽

10.2352/j.imagingsci.technol.2020.64.2.020503 ◽

2020 ◽

Vol 64 (2) ◽

pp. 20503-1-20503-5

Author(s):

Faiz Wali ◽

Shenghao Wang ◽

Ji Li ◽

Jianheng Huang ◽

Yaohu Lei ◽

...

Keyword(s):

Image Quality ◽

Phase Contrast ◽

Quality Analysis ◽

Phase Contrast Imaging ◽

Phase Image ◽

Contrast Imaging ◽

High Quality ◽

Image Quality Analysis ◽

X Ray ◽

Grating Interferometer

Abstract Grating-based x-ray phase-contrast imaging has the potential to enhance image quality and provide inner structure details non-destructively. In this work, using grating-based x-ray phase-contrast imaging system and employing integrating-bucket method, the quantitative expressions of signal-to-noise ratios due to photon statistics and mechanical error are analyzed in detail. Photon statistical noise and mechanical error are the main sources affecting the image noise in x-ray grating interferometry. Integrating-bucket method is a new phase extraction method translated to x-ray grating interferometry; hence, its image quality analysis would be of great importance to get high-quality phase image. The authors’ conclusions provide an alternate method to get high-quality refraction signal using grating interferometer, and hence increases applicability of grating interferometry in preclinical and clinical usage.

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