Impact of Anesthesia and Surgery for Congenital Heart Disease on the Vitamin D Status of Infants and Children

2014 ◽  
Vol 58 (2) ◽  
pp. 81-82
Author(s):  
J. Dayre McNally ◽  
Kusum Menon ◽  
Pranesh Chakraborty ◽  
Lawrence Fisher ◽  
Kathryn A. Williams ◽  
...  
Keyword(s):  
Vitamin D ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Infants And Children ◽  
Vitamin D Status

Impact of Anesthesia and Surgery for Congenital Heart Disease on the Vitamin D Status of Infants and Children

2013 ◽  
Vol 119 (1) ◽  
pp. 71-80 ◽  
Author(s):  
J. Dayre McNally ◽  
Kusum Menon ◽  
Pranesh Chakraborty ◽  
Lawrence Fisher ◽  
Kathryn A. Williams ◽  
...  
Keyword(s):  
Vitamin D ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Clinical Course ◽  
Tertiary Care ◽  
Vitamin D Status ◽  
Organ Systems ◽  
Vitamin D Levels ◽  
The Impact

Abstract Background: Vitamin D is recognized as a pleiotropic hormone important for the functioning of organ systems, including those central to critical illness pathophysiology. Recent studies have reported associations between vitamin D status and outcome among critically ill adults and children. Preoperative vitamin D status, impact of operative techniques, and relationship between immediate postoperative vitamin D levels and clinical course have not been described in the pediatric congenital heart disease (CHD) population. The objective of this study was to describe the impact of CHD surgery on vitamin D status and relationship between postoperative levels and clinical course. Methods: A prospective cohort study was conducted from 2009 to 2011 at a single tertiary care pediatric hospital. A total of 58 children with CHD were enrolled and blood collected preoperatively, intraoperatively, and postoperatively. Serum 25-hydroxyvitamin D (25OHD) was measured using liquid chromatography–mass spectrometry. Results: The mean preoperative 25OHD was 58.0 nm (SD, 22.4), with 42% being deficient (<50 nm). Postoperatively, we identified a 40% decline in 25OHD to 34.2 nm (SD, 14.5) with 86% being deficient. Intraoperative measurements determined that initiation of cardiopulmonary bypass coincided with abrupt decline. CHD patients requiring catecholamines had lower postoperative 25OHD (38.2 vs. 26.5 nm, P = 0.007), findings confirmed through multivariate logistic regression. Lower postoperative 25OHD was associated with increased fluid requirements and intubation duration. Conclusions: Most CHD patients are vitamin-D deficient postoperatively due to low preoperative levels and a significant intraoperative decline. Interventional studies will be required to determine whether prevention of postoperative vitamin D deficiency improves outcome.

scholarly journals Vitamin D Status in Neonates with Congenital Heart Disease: Its Changes with Heart Surgery and Relation to the Outcome

2022 ◽  
Vol 30 (1) ◽  
pp. 1-7
Author(s):  
Ziba Mosayebi ◽  
◽  
Mohamadreza Mirzaaghayan ◽  
Aliakbar Zeinaloo ◽  
Behdad Gharib ◽  
...  
Keyword(s):  
Vitamin D ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Vitamin D Status

Junctional tachycardia in infants and children after open heart surgery for congenital heart disease

1987 ◽  
Vol 59 (12) ◽  
pp. 1216-1218 ◽  
Author(s):  
James W. Grant ◽  
Gerald A. Serwer ◽  
Brenda E. Armstrong ◽  
H.Newland Oldham ◽  
Page A.W. Anderson
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Infants And Children ◽  
Open Heart ◽  
Junctional Tachycardia ◽  
In Infants And Children

Three-dimensional cine MRI in free-breathing infants and children with congenital heart disease

2009 ◽  
Vol 39 (12) ◽  
pp. 1333-1342 ◽  
Author(s):  
Achim Seeger ◽  
Michael C. Fenchel ◽  
Gerald F. Greil ◽  
Petros Martirosian ◽  
Ulrich Kramer ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Three Dimensional ◽  
Free Breathing ◽  
Infants And Children ◽  
Cine Mri

Compression of the central airways by a dilated aorta in infants and children with congenital heart disease

1999 ◽  
Vol 67 (4) ◽  
pp. 1130-1136 ◽  
Author(s):  
Doff B McElhinney ◽  
V.Mohan Reddy ◽  
Mark S Pian ◽  
Phillip Moore ◽  
Frank L Hanley
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Infants And Children ◽  
In Infants And Children
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