Are Optimal Cerebral Perfusion Pressure and Cerebrovascular Autoregulation Related to Long-term Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage?

2012 ◽  
Vol 24 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Frank Anthony Rasulo ◽  
Alan Girardini ◽  
Andrea Lavinio ◽  
Elena De Peri ◽  
Roberto Stefini ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Cerebral Perfusion Pressure ◽  
Cerebral Perfusion ◽  
Perfusion Pressure ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Cerebrovascular Autoregulation ◽  
Optimal Cerebral Perfusion Pressure

scholarly journals Assessment of the Subarachnoid Hemorrhage International Trialists (SAHIT) Models for Dichotomized Long-Term Functional Outcome Prediction After Aneurysmal Subarachnoid Hemorrhage in a United Kingdom Multicenter Cohort Study

Neurosurgery ◽  
2020 ◽  
Author(s):  
Isabel C Hostettler ◽  
Menelaos Pavlou ◽  
Gareth Ambler ◽  
Varinder S Alg ◽  
Stephen Bonner ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Functional Outcome ◽  
Outcome Prediction ◽  
Prediction Models ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Predictive Performance ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Fisher Grade

Abstract BACKGROUND Long-term outcome after subarachnoid hemorrhage, beyond the first few months, is difficult to predict, but has critical relevance to patients, their families, and carers. OBJECTIVE To assess the performance of the Subarachnoid Hemorrhage International Trialists (SAHIT) prediction models, which were initially designed to predict short-term (90 d) outcome, as predictors of long-term (2 yr) functional outcome after aneurysmal subarachnoid hemorrhage (aSAH). METHODS We included 1545 patients with angiographically-proven aSAH from the Genetic and Observational Subarachnoid Haemorrhage (GOSH) study recruited at 22 hospitals between 2011 and 2014. We collected data on age, WNFS grade on admission, history of hypertension, Fisher grade, aneurysm size and location, as well as treatment modality. Functional outcome was measured by the Glasgow Outcome Scale (GOS) with GOS 1 to 3 corresponding to unfavorable and 4 to 5 to favorable functional outcome, according to the SAHIT models. The SAHIT models were assessed for long-term outcome prediction by estimating measures of calibration (calibration slope) and discrimination (area under the receiver-operating characteristic curve [AUC]) in relation to poor clinical outcome. RESULTS Follow-up was standardized to 2 yr using imputation methods. All 3 SAHIT models demonstrated acceptable predictive performance for long-term functional outcome. The estimated AUC was 0.71 (95% CI: 0.65-0.76), 0.73 (95% CI: 0.68-0.77), and 0.74 (95% CI: 0.69-0.79) for the core, neuroimaging, and full models, respectively; the calibration slopes were 0.86, 0.84, and 0.89, indicating good calibration. CONCLUSION The SAHIT prediction models, incorporating simple factors available on hospital admission, show good predictive performance for long-term functional outcome after aSAH.

Cerebrospinal Fluid Concentrations of Nimodipine Correlate With Long-term Outcome in Aneurysmal Subarachnoid Hemorrhage

2019 ◽  
Vol 42 (5) ◽  
pp. 157-162 ◽  
Author(s):  
Roberto Riva ◽  
Marianna Pegoli ◽  
Manuela Contin ◽  
Alessandro Perrone ◽  
Susan Mohamed ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Term Outcome ◽  
Long Term Outcome

Long-term outcome after aneurysmal subarachnoid hemorrhage—risks of vascular events, death from cancer and all-cause death

2013 ◽  
Vol 261 (2) ◽  
pp. 309-315 ◽  
Author(s):  
Dennis J. Nieuwkamp ◽  
Arno de Wilde ◽  
Marieke J. H. Wermer ◽  
Ale Algra ◽  
Gabriël J. E. Rinkel
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Vascular Events ◽  
Term Outcome ◽  
Long Term Outcome

Pupillary Reactivity Upon Hospital Admission Predicts Long-term Outcome in Poor Grade Aneurysmal Subarachnoid Hemorrhage Patients

2007 ◽  
Vol 8 (3) ◽  
pp. 374-379 ◽  
Author(s):  
William J. Mack ◽  
Zachary L. Hickman ◽  
Andrew F. Ducruet ◽  
James T. Kalyvas ◽  
Matthew C. Garrett ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Hospital Admission ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Poor Grade ◽  
Pupillary Reactivity

Non-aneurysmal subarachnoid hemorrhage in 173 patients: a prospective study of long-term outcome

2015 ◽  
Vol 22 (10) ◽  
pp. 1329-1336 ◽  
Author(s):  
J. Konczalla ◽  
J. Schmitz ◽  
S. Kashefiolasl ◽  
C. Senft ◽  
V. Seifert ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Prospective Study ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Term Outcome ◽  
Long Term Outcome ◽  
A Prospective Study
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