Acoustic noise is pervasive in human environments. Some individuals are more tolerant to noise than others. We demonstrate the explanatory potential of Big-5 personality traits neuroticism (being emotionally unstable) and extraversion (being enthusiastic, outgoing) on subjective self-report and objective psycho-acoustic metrics of noise tolerance in two samples (total N = 1,103). Under statistical control for demographics and in agreement with pre-registered hypotheses, lower neuroticism and higher extraversion independently explained superior self-reported noise resistance, speech-in-noise comprehension, and acceptable background noise. Surprisingly, objective speech-in-noise comprehension instead increased with higher levels of neuroticism. In turn, the bias to subjectively overrate one’s own objective noise tolerance decreases with higher neuroticism but increases with higher extraversion. Of benefit to a solid framework of noise tolerance and tailored audiological treatments, these results show that personality explains inter-individual differences in coping with acoustic noise, which is a ubiquitous source of distraction and health hazard.