Innovative Vibrating Hydraulic Dredge for Striped Venus (Chamelea gallina) Fishing

This work proposes the experimentation of an innovative hydraulic dredge for clam fishing (Chamelea gallina) in the Adriatic Sea (Italy). This innovative gear aimed at increasing the selectivity of the typical hydraulic dredge used currently, while at the same reducing the impact on benthos through the conception, installation, and experimentation of innovative technological solutions, consisting mainly of a vibrating bottom panel on the dredge and a “warning device” on the dredge mouth. Comparative experiments of the traditional vs. the modified gear, employing two boats fishing in parallel on the northern coast of Abruzzi (Adriatic Sea) and contrasting the catch with both paired comparisons and through modelling, showed that the innovative hydraulic dredge retains fewer undersize clams while yielding similar amounts of commercial product, moreover of higher quality; at the same time, it takes on board less discard, and catches significantly less vagile fauna. In short, the innovative gear is gaining five times over a list of six parameters considered as positive and/or advantageous for the clam fishery. The results allow proposals of potential improvements to clam-fishing instruments to make the selection processes more effective while promoting a lower impacting fishery, which is essential for clam management.

The Saliency of Snake Scales and Leopard Rosettes to Infants: Its Relevance to Graphical Patterns Portrayed in Prehistoric Art

Geometrically arranged spots and crosshatched incised lines are frequently portrayed in prehistoric cave and mobiliary art. Two experiments examined the saliency of snake scales and leopard rosettes to infants that are perceptually analogous to these patterns. Experiment 1 examined the investigative behavior of 23 infants at three daycare facilities. Four plastic jars (15×14.5cm) with snake scales, leopard rosettes, geometric plaid, and plain patterns printed on yellowish-orange paper inside were placed individually on the floor on separate days during playtime. Fourteen 7–15-month-old infants approached each jar hesitantly and poked it before handling it for five times, the criterion selected for statistical analyses of poking frequency. The jars with snake scales and leopard rosettes yielded reliably higher poking frequencies than the geometric plaid and plain jars. The second experiment examined the gaze and grasping behavior of 15 infants (spanning 5months of age) seated on the laps of their mothers in front of a table. For paired comparisons, the experimenter pushed two of four upright plastic cylinders (13.5×5.5cm) with virtually the same colored patterns simultaneously toward each infant for 6s. Video recordings indicated that infants gazed significantly longer at the cylinders with snake scales and leopard rosettes than the geometric plaid and plain cylinders prior to grasping them. Logistic regression of gaze duration predicting cylinder choice for grasping indicated that seven of 24 paired comparisons were not significant, all of which involved choices of cylinders with snake scales and leopard rosettes that diverted attention before reaching. Evidence that these biological patterns are salient to infants during an early period of brain development might characterize the integration of subcortical and neocortical visual processes known to be involved in snake recognition. In older individuals, memorable encounters with snakes and leopards coupled with the saliency of snake scales and leopard rosettes possibly biased artistic renditions of similar patterns during prehistoric times.

G0 Revisited as Equally Bright Reference Boundary

Brilliance and zero grayness (denoted as G0) and are two terms coined by Ralph Evans. Nayatani, Heckaman and Fairchild have done series of work to incorporate them into comprehensive color appearance models. In this work, those concepts were reexamined to scale lightness/brightness across the chromaticity diagram. Specifically, observers, mostly with a color science background, were asked to adjust the luminance of a color patch to appear with no grayness, or equivalently just about/cease to glow. The hypothesis was that lightness can be equalized across those chromaticities and the Helmholtz-Kohlrausch effect is automatically incorporated. This hypothesis was verified in a follow-up experiment where another group of observers completed paired comparisons of the brightness between the collected G0 results. The G0 task was also repeated under another two levels of adaption backgrounds, based on which different absolute brightness results for a given chromaticity might be derived. In addition, high correlations between the G0 results (as a perceptual boundary between appearance modes) and different physical gamut boundaries including MacAdam's optimal colors were found for possible computational proxies and ecologically meaningful implications.

Paired comparisons of mutational profiles before and after brachytherapy in asian uveal melanoma patients

Uveal melanoma(UM) is the most common primary intraocular malignancy in adults. However, the incidence of UM in Asia is 10 to 20 times less than in Western populations. Therefore, for the first time, we report our whole exome sequencing (WES) data analysis to discover differences in the molecular features of Asian and Western UM, and to determine the disparities between the primary tumor before brachytherapy and enucleated samples after brachytherapy. WES of 19 samples (13 primary tumors, 5 enucleation samples after brachytherapy, and 1 liver metastasis) from 13 patients diagnosed with UM and treated between 2007 and 2019 at the Yonsei University Health System (YUHS) were analyzed using bioinformatics pipelines. We identified significantly altered genes in Asian UM and changes in mutational profiles before and after brachytherapy using various algorithms. GNAQ, BAP1, GNA11, SF3B1 and CYSLTR2 were significantly mutated in Asian UM, which is similar that reported frequently in previous Western-based UM studies. There were also similar copy number alterations (M3, 1p loss, 6p gain, 8q gain) in both groups. In paired comparisons of the same patients, DICER1 and LRP1B were distinctly mutated only in tumor samples obtained after brachytherapy using rare-variant association tests (P = 0.01, 0.01, respectively). The mutational profiles of Asian UM were generally similar to the data from previous Western-based studies. DICER1 and LRP1B were newly mutated genes with statistical significance in the regrowth samples after brachytherapy compared to the primary tumors, which may be related to resistance to brachytherapy.

INDOOR ENVIRONMENTAL QUALITY IN THE JORDANIAN CONTEXT: INFLUENCE ON OCCUPANTS’ SATISFACTION

ABSTRACT The applicability of building rating systems has gained attention for achieving indoor environmental quality. Considering the wider internationalized recognition of LEED (Leadership in Energy and Environmental Design) and other rating systems, the case of Jordan provides a sense of particularity in consideration to its rather recent history in acknowledging these progressive standards. Utilizing a mixed approach based on paired comparisons between local LEED and non-LEED certified buildings, this research paper explores the level of satisfaction pertaining to Indoor Environmental Quality of building occupants. While it touches on the generality of such satisfaction, it proceeds to unpack and investigate how it resonates with the sustainability of the building measured through various means. The research outcomes reflected an overall appeal of LEED certified buildings and a decent level of comfort of their dwellers. Yet, it conveyed a vague, rather sporadic relation when comparing the subjective perception to the objective measures due to multiple potential reasons. The paper concludes by stressing the need for further appropriation of international environmental codes to better suit the local context. It lays a reliable foundation for further research, utilizing more case studies and exploring the applicability of rating systems in Jordan.

Effects on suicidal risk: Comparison of clozapine to other newer medicines indicated to treat schizophrenia or bipolar disorder

Background: Clozapine is the only treatment with regulatory-recognition of lowering suicidal risk, at least in schizophrenia patients. It remains uncertain whether such effects extend to other drugs for psychosis. Methods: We searched for reports on rates of suicidal behavior during treatment with clozapine and other modern drugs for psychosis (aripiprazole, olanzapine, risperidone, quetiapine, and ziprasidone) versus comparison or control treatments and analyzed the contrasts by random-effect meta-analysis to obtain pooled odds ratios (ORs) with 95% confidence intervals (CIs). Results: We identified 35 paired comparisons of modern drugs for psychosis versus comparison or control treatments in 18 reports. There was moderate overall superiority of all agents tested over alternatives (OR = 0.522, p = 0.004). With clozapine, this effect was large (OR = 0.229, p < 0.0001) and consistent (7/7 trials), but significant antisuicidal effects were not found with other drugs for psychosis in 28 other trials (OR = 0.941, p = 0.497). Apparent efficacy of specific agents ranked: risperidone ⩾ olanzapine ⩾ aripiprazole ⩾ ziprasidone ⩾ mixed drugs for psychosis ⩾ quetiapine, but none of these differences was significant. Conclusions: An ability of clozapine to reduce risk of suicides and attempts in schizophrenia patients appears to be a unique effect not shared with other modern medicines indicated for schizophrenia or bipolar disorder.

Do informal reasoning fallacies really shape decisions? Experimental evidence

Informal reasoning fallacies belong to a persuasive tactic, leading to a conclusion that is not supported by premises but reached through emotions and/or misleading and incomplete information. Previous research focused on the ability to recognize informal reasoning fallacies. However, the recognition itself does not necessarily mean immunity to their influence on decisions made. An experiment was designed to study the relationship between the presence of informal reasoning fallacies and a consequent decision. Having conducted paired comparisons of distributions, we have found some support for the hypothesis that informal reasoning fallacies affect decision-making more substantially than non-fallacious reasoning—strong support in the case of a slippery slope, weak in that of appeal to fear, anecdotal evidence argument defying evaluation. Numeracy and cognitive reflection seem to be associated with higher resistance to the slippery slope, but do not diminish appeal to fear.

Mash Sketched Reference Dataset for Genome-Based Taxonomy and Comparative Genomics

The analysis of curated genomic, metagenomic, and proteomic data are of paramount importance in the fields of biology, medicine, education, and bioinformatics. Although this type of data is usually hosted in raw form in free international repositories, its access requires plenty of computing, storage, and processing capacities for the domestic user. The purpose of the study is to offer a comprehensive set of genomic and proteomic reference data, in an accessible and easy-to-use form to the scientific community. A representative type material set of genomes, proteomes and metagenomes were directly downloaded from the site: https://www.ncbi.nlm.nih.gov/assembly/ and from Genome Taxonomy Database, associated with the major groups of Bacteria, Archaea, Virus, and Fungi. Sketched databases were subsequently created and stored on handy raw reduced representations, by using Mash software. Our dataset contains near to 100 GB of space disk reduced to 585.78 MB and represents 87,476 genomics/proteomic records from eight informative contexts, which have been prefiltered to make them accessible, usable, and user-friendly with computational resources. Potential uses of this dataset include but are not limited to, microbial species delimitation, estimation of genomic distances, genomic novelties, paired comparisons between proteomes, genomes, and metagenomes.

METHOD OF MAKING DECISIONS ON DETERMINING RELATIVE RISK OF ENERGY SYSTEM SECTIONS INOPERABILITY

The article considers the application of the analytic hierarchy method in the problem of determining the relative value of the energy system sections operability. The process of building a hierarchy is described for the sections of the energy system, which are assessed by the groups of criteria and by the component criteria. There is shown the process of filling in scores and matrices of paired comparisons, as well as calculating the components of priority vectors for each of the hierarchy levels. The analytical expressions are formulated for the synthesis of priorities and determination of the values of the relative risk of inoperability for each of the sections. A diagram is constructed showing the relative risk of inoperability of individual sections of the energy system