Prospective Evaluation of a Treatment Protocol Based on Fracture Displacement for Pediatric Lateral Condyle Humerus Fractures: A Preliminary Study

Summary Objective: Severe thrombocytopenia is a common sequelae to heat stroke in dogs. So far it has been hypothezised that it is due to disseminated intravascular coagulation. We hypothezised that it is due to immune mediated destruction via antiplatelet antibodies. Material and methods: Prospective evaluation of dogs with heat stroke from May 2005 to August 2008. Dogs that developed severe thrombocytopenia within 5 days of admission were included in the study. All dogs were treated with a standardized treatment protocol. In addition, they received either immunoglobulins or prednisolone. Results: Six dogs were presented with heat stroke during that time period. Four developed a severe thrombocytopenia. All four dogs tested positive for antiplatelet antibodies and did not have elevated D-Dimers at that time. Platelet count in three dogs recovered fully, one dog was euthanized due to liver and renal failure. Conclusion: In those cases thrombocytopenia was due to immune mediated destruction not due to DIC. Clinical rele-vance: Due to the severity of the thrombocytopenia and the high risk for bleeding in those patients, immunosuppressive therapy in addition to DIC prophylaxis should be discussed.

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Conservative Treatment Protocol of Odontogenic Keratocyst: A Preliminary Study

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2005.11.007 ◽

2006 ◽

Vol 64 (3) ◽

pp. 379-383 ◽

Cited By ~ 93

Author(s):

Paul Edward Maurette ◽

Jacks Jorge ◽

Márcio de Moraes

Keyword(s):

Conservative Treatment ◽

Treatment Protocol ◽

Odontogenic Keratocyst ◽

Preliminary Study

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PROSPECTIVE EVALUATION OF A DIAGNOSTIC AND TREATMENT PROTOCOL FOR VENTILATOR-ASSOCIATED PNEUMONIA (VAP) IN SICU PATIENTS

Critical Care Medicine ◽

10.1097/00003246-200212001-00397 ◽

2002 ◽

Vol 30 (Supplement) ◽

pp. A116 ◽

Cited By ~ 1

Author(s):

Shilpa K Parbhoo ◽

Michelle M Gearhart ◽

Michelle L Dusing ◽

Steven E Pass

Keyword(s):

Treatment Protocol ◽

Ventilator Associated Pneumonia ◽

Prospective Evaluation

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Graves' disease in pregnancy: Prospective evaluation of a selective invasive treatment protocol

American Journal of Obstetrics and Gynecology ◽

10.1067/mob.2003.321 ◽

2003 ◽

Vol 189 (1) ◽

pp. 159-165 ◽

Cited By ~ 78

Author(s):

Zohar Nachum ◽

Yardena Rakover ◽

Ehud Weiner ◽

Eliezer Shalev

Keyword(s):

Treatment Protocol ◽

Graves Disease ◽

Prospective Evaluation ◽

Invasive Treatment ◽

In Pregnancy

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Significance of Addressal of Clinical Investigations of Kidney Functions in Recovery/Mortality of Certain COVID-19 Patients

Bioscience Biotechnology Research Communications ◽

10.21786/bbrc/14.4.89 ◽

2021 ◽

Vol 14 (4) ◽

pp. 1985-1991

Author(s):

Bennet Angel

Keyword(s):

Treatment Protocol ◽

Chloride Ions ◽

Present Observation ◽

Potassium Ions ◽

Clinical Investigations ◽

Preliminary Study ◽

Degree Of Association ◽

Kidney Functions ◽

Sodium And Potassium ◽

Robust Protocol

Clinical management of COVID-19 patients through a robust protocol is key to the good recovery and reduced mortality of patients. Efficient kidney functions during treatment period can contribute for improvised recovery and reduced mortality of patients. Analysis of the kidney function among Recovered and Dead cases of COVID-19 was made to reveal the degree of association of kidney functions with the two categories of patients. 83.4% of recovered patients did not show hyper values of blood urea whereas 72.5% of dead patients showed hyper-urea level in blood. 88.8% of survivors showed non-hyper creatinine level of blood whereas only 40% of dead cases showed hyper creatine level. Strong degree of association of blood urea with recovery/mortality was observed. Sodium levels were seen to be low while potassium and chloride ions were seen to be high in COVID-19 individuals. Our preliminary study suggests that kidney functions especially the value of blood urea and creatinine need to be addressed during COVID-19 patients to ensure the best recovery and reduced mortality. After more number of case studies, the present observation could sensitize consideration for inclusion of addressal and treatment of kidney functions into treatment protocol against COVID-19. It was also interesting to observe that levels of sodium and potassium ions among Survivors and Dead cases have impacted function of the essential ion channels in patient’s physiology.

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Image Fusion of X-ray and Magnetic Resonance Imaging-Based Evaluation of the Stability of Pediatric Lateral Humeral Condyle Fracture

10.32592/ircmj.2021.23.8.1234 ◽

2021 ◽

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Lateral Condyle ◽

Resonance Imaging ◽

Condylar Fracture ◽

X Ray ◽

Fracture Displacement ◽

The Stability ◽

Condyle Fracture ◽

Humeral Condyle

Background: Lateral humeral condyle fracture is the second most common intra-articular fracture in pediatric elbow. Objectives: The present study aimed to analyze the differences between X-ray and magnetic resonance imaging (MRI) in the evaluation of the stability of pediatric lateral humeral condyle fracture and the degree of fracture displacement. Methods: A total of 78 patients with acute elbow trauma were selected and hospitalized in our orthopedic department from July 2018-July 2019. All patients were examined with X-ray and MRI. The sensitivity and specificity of X-ray and MRI in the diagnosis of lateral humeral condyle fracture and the integrity of the trochlear cartilage chain fracture were calculated. The X-ray and MRI were examined respectively to check the value of lateral and posterior fracture space of lateral humeral condyle fracture. Results: Callus repair was observed according to the observation of fracture line during operation or the follow-up imaging examination of conservative treatment. It was confirmed that out of 78 patients with elbow joint trauma, 72 cases were diagnosed with the fracture of lateral condyle of humerus, and the other 6 patients were cured without fracture signs. The sensitivity of MRI in the diagnosis of pediatric lateral condylar fracture was 100%, which was significantly higher than that of X-ray (88.89%) (P<0.05). The results of X-ray and MRI in the diagnosis of pediatric lateral condylar fracture were generally consistent (kappa value = 0.465;< 0.01). Among the 72 confirmed cases, 35 subjects had a fracture of trochlear cartilage chain. The sensitivity of MRI in the diagnosis of pediatric fracture of lateral condyle of humerus was 97.14%, which was significantly higher than that of X-ray (62.86%) (P<0.05). The difference was statistically significant (P<0.05). The sensitivity of 3d-fs-fspgr or 3d-fspgr was significantly higher than that of fs-t2wi and fs-pdwi (P< 0.05). Conclusion: As evidenced by the obtained results, MRI was superior to X-ray in the diagnosis of pediatric humeral epicondylar fracture stability and evaluation of fracture displacement. Furthermore, 3d-fs-fspgr or 3d-fspgr was the best MR sequence to show the pediatric humeral epicondylar fracture. These findings can provide theoretical basis for the establishment of clinical treatment plan.

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