Necrotizing Granulomas in a Patient With Psoriasis and Sarcoidosis After Adalimumab—Medication-Induced Reaction or Reactivation of Latent Disease?

2019 ◽  
Vol 41 (9) ◽  
pp. 661-666 ◽  
Author(s):  
Yana Turkowski ◽  
Nellie Konnikov ◽  
Meera Mahalingam
2019 ◽  
Vol 19 (8) ◽  
pp. 567-578 ◽  
Author(s):  
Marcus Vinicius Nora de Souza ◽  
Thais Cristina Mendonça Nogueira

Nowadays, tuberculosis (TB) is an important global public health problem, being responsible for millions of TB-related deaths worldwide. Due to the increased number of cases and resistance of Mycobacterium tuberculosis to all drugs used for the treatment of this disease, we desperately need new drugs and strategies that could reduce treatment time with fewer side effects, reduced cost and highly active drugs against resistant strains and latent disease. Considering that, 4H-1,3-benzothiazin-4-one is a promising class of antimycobacterial agents in special against TB-resistant strains being the aim of this review the discussion of different aspects of this chemical class such as synthesis, mechanism of action, medicinal chemistry and combination with other drugs.


1995 ◽  
Vol 60 (1) ◽  
pp. 104-114 ◽  
Author(s):  
Boyd L. Earl ◽  
Richard L. Titus

Previous reports on the thermal or CO2-laser induced decomposition of trichloroethylene have identified only one condensible product, hexachlorobenzene (in addition to HCl and mono- and dichloroacetylene). We have found that trichloroethylene vapor exposed to cw irradiation on the P(24) line of the (001 - 100) band of the CO2 laser at incident power levels from 8 - 17 W produces numerous products, of which the 13 major ones have been identified using IR, GC/MS, GC/FTIR, and NMR methods. All of these products have 4, 6, or 8 carbons, are highly unsaturated, and are completely chlorinated or contain a single hydrogen. C4HCl5 and C6Cl6 isomers (three of each) account for S 55% to 85% of total products (based on peak areas in the total ion chromatograms in GC/MS runs), depending on reaction conditions. In addition to characterizing the products, we discuss the dependence of the product distribution on laser power, irradiation time, and cell geometry, and we outline a possible mechanism.


2021 ◽  
pp. 138572
Author(s):  
Jing Guo ◽  
Ye-Jun Li ◽  
Jun-Ping Ma ◽  
Xian Tang ◽  
Xue-Shen Liu

2010 ◽  
Vol 132 (13) ◽  
pp. 134903 ◽  
Author(s):  
Alessio Zaccone ◽  
Daniele Gentili ◽  
Massimo Morbidelli

2006 ◽  
Vol 20 (1) ◽  
pp. 142-147 ◽  
Author(s):  
Zan Qu ◽  
Naiqiang Yan ◽  
Yanfei Zhao ◽  
Jinping Jia ◽  
Dan Wu

1981 ◽  
Vol 90 (5) ◽  
pp. 1267-1274 ◽  
Author(s):  
Tarou OGURUSU ◽  
Akio MAEDA ◽  
Norihiro SASAKI ◽  
Tôni YOSHIZAWA
Keyword(s):  
Low Salt ◽  

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