scholarly journals Identification of clusters of individuals relevant to temporomandibular disorders and other chronic pain conditions

Pain ◽  
2016 ◽  
Vol 157 (6) ◽  
pp. 1266-1278 ◽  
Author(s):  
Eric Bair ◽  
Sheila Gaynor ◽  
Gary D. Slade ◽  
Richard Ohrbach ◽  
Roger B. Fillingim ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Temporomandibular Disorders ◽  
Chronic Pain Conditions

The prevalence of comorbid chronic pain conditions among patients with temporomandibular disorders

2021 ◽  
Author(s):  
Bethea A. Kleykamp ◽  
McKenzie C. Ferguson ◽  
Ewan McNicol ◽  
Ida Bixho ◽  
Lesley M. Arnold ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Temporomandibular Disorders ◽  
Chronic Pain Conditions

scholarly journals Neural Mechanisms of Temporomandibular Joint and Masticatory Muscle Pain: A Possible Role for Peripheral Glutamate Receptor Mechanisms

2005 ◽  
Vol 10 (3) ◽  
pp. 145-152 ◽  
Author(s):  
David K Lam ◽  
Barry J Sessle ◽  
Brian E Cairns ◽  
James W Hu
Keyword(s):  
Chronic Pain ◽  
Glutamate Receptors ◽  
Temporomandibular Joint ◽  
Temporomandibular Disorders ◽  
Muscle Pain ◽  
Neuronal Excitability ◽  
Experimental Pain ◽  
Ionotropic Glutamate Receptors ◽  
Peripheral Tissues ◽  
Chronic Pain Conditions

The purpose of the present review is to correlate recent knowledge of the role of peripheral ionotropic glutamate receptors in the temporomandibular joint and muscle pain from animal and human experimental pain models with findings in patients. Chronic pain is common, and many people suffer from chronic pain conditions involving deep craniofacial tissues such as temporomandibular disorders or fibromyalgia. Animal and human studies have indicated that the activation of peripheral ionotropic glutamate receptors in deep craniofacial tissues may contribute to muscle and temporomandibular joint pain and that sex differences in the activation of glutamate receptors may be involved in the female predominance in temporomandibular disorders and fibromyalgia. A peripheral mechanism involving autocrine and/or paracrine regulation of nociceptive neuronal excitability via injury or inflammation-induced release of glutamate into peripheral tissues that may contribute to the development of craniofacial pain is proposed.

Sleep and pain

2017 ◽  
Author(s):  
Gilles J. Lavigne ◽  
Samar Khoury ◽  
Caroline Arbour ◽  
Nadia Gosselin
Keyword(s):  
Primary Care ◽  
Traumatic Brain Injury ◽  
Chronic Pain ◽  
Temporomandibular Disorders ◽  
Sleep Disturbances ◽  
Poor Sleep ◽  
Sleep Complaints ◽  
Nonrestorative Sleep ◽  
Theoretical Perspectives ◽  
Chronic Pain Conditions

While sleep disturbances are highly prevalent in primary care populations, the patients with the highest rate of poor sleep complaints, including insomnia and nonrestorative sleep, are those with pain. In this chapter, a summary of the potential shared or interactive mechanisms underlying the coexistence of sleep and pain in chronic pain conditions is presented. Theoretical perspectives illustrating sleep–pain interactions are described, as well as the latest empirical evidence regarding sleep disruptions in the context of chronic widespread musculoskeletal pain, fibromyalgia, temporomandibular disorders, headaches, and mild traumatic brain injury. Finally, multidimensional strategies for the co-management of sleep and pain are proposed and discussed.

Amitriptyline treatment of chronic pain in patients with temporomandibular disorders

2000 ◽  
Vol 27 (10) ◽  
pp. 834-841 ◽  
Author(s):  
O. Plesh ◽  
D. Curtis ◽  
J. Levine ◽  
W. D. Mccall Jr
Keyword(s):  
Chronic Pain ◽  
Temporomandibular Disorders

Retrospective analysis on the effect of spinal cord stimulation on opioid consumption

2020 ◽  
Author(s):  
Awinita Barpujari ◽  
Michael A Erdek
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Retrospective Analysis ◽  
Spinal Cord Stimulation ◽  
Alternative Therapy ◽  
Opioid Consumption ◽  
Opioid Use ◽  
Number Of Patients ◽  
Chronic Pain Conditions ◽  
Post Trial

Aim: Spinal cord stimulation (SCS) is used to clinically manage and/or treat several chronic pain etiologies. A limited amount is known about the influence on patients' use of opioid pain medication. This retrospective analysis evaluated SCS effect on opioid consumption in patients presenting with chronic pain conditions. Materials & methods: Sixty-seven patients underwent a temporary trial device, permanent implant or both. Patients were divided for assessment based on the nature of their procedure(s). Primary outcome was change in morphine equivalent dose (MED), ascertained from preoperative and postoperative medication reports. Results: Postoperative MED was significantly lower in patients who received some form of neuromodulation therapy. Pretrial patients reported an average MED of 41.01 ± 10.23 mg per day while post-trial patients reported an average of 13.30 ± 5.34 mg per day (p < 0.001). Pre-implant patients reported an average MED of 39.14 ± 13.52 mg per day while post-implant patients reported an average MED of 20.23 ± 9.01 mg per day (p < 0.001). There were no significant differences between pre-trial and pre-implant MED, nor between post-trial and post-implant MED. Of the 42 study subjects who reported some amount of pre-intervention opioid use, 78.57% indicated a lower MED (n = 33; p < 0.001), 16.67% indicated no change (n = 7) and 4.76% (n = 2) indicated a higher MED, following intervention. Moreover, SCS therapy resulted in a 26.83% reduction (p < 0.001) in the number of patients with MED >50 mg per day. Conclusion: Spinal cord stimulation may reduce opioid use when implemented appropriately. Neuromodulation may represent alternative therapy for alleviating chronic pain which may avoid a number of deleterious side effects commonly associated with opioid consumption.

scholarly journals Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine

2021 ◽  
Vol 3 (5) ◽  
pp. e383-e392
Author(s):  
Jo Nijs ◽  
Steven Z George ◽  
Daniel J Clauw ◽  
César Fernández-de-las-Peñas ◽  
Eva Kosek ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Precision Medicine ◽  
Central Sensitisation ◽  
Chronic Pain Conditions

scholarly journals Patients referred to a German TMD-specialized consultation hour—a retrospective on patients without a diagnosis according to RDC/TMD decision trees

2021 ◽  
Author(s):  
Angelika Rauch ◽  
Sebastian Hahnel ◽  
Anita Kloss-Brandstätter ◽  
Oliver Schierz
Keyword(s):  
Chronic Pain ◽  
Oral Health ◽  
Decision Trees ◽  
Temporomandibular Disorders ◽  
Depression Scale ◽  
Health Impact ◽  
Physical Symptoms ◽  
Pain Scale ◽  
Related Quality ◽  
Health Related

Abstract Objectives The objective was to describe the physical and psychosocial features of patients attending a specialized consultation hour for temporomandibular disorders (TMD). This investigation focused on those patients who did not receive a diagnosis according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Materials and methods From 2004 to 2017, patients seeking care during a TMD-specialized consultation hour were consecutively recruited. Each patient completed a TMD-related questionnaire, psychosocial questionnaires (Graded Chronic Pain Scale, Hospital Anxiety and Depression Scale, Beschwerden-Liste), and the Oral Health Impact Profile-49. The clinical examination was performed according to the RDC/TMD. Results The mean age of the 1020 patients was 43.3 years (75.3% female). According to the RDC/TMD decision trees, 351 patients were categorized without a TMD diagnosis (NoTMDdx). The most frequent reasons for seeking care were orofacial pain/TMJ pain or headaches revealing an OR of 1.89 (for TMDdx group). A relevant proportion of patients was categorized as positive for anxiety (NoTMDdx/TMDdx 30.8/41.2%; p = 0.072), depression (20.8/23.9%; p = 0.433), non-specific physical symptoms (31.4/44.1%; p < 0.001), or dysfunctional chronic pain (11.5/18.2%; p < 0.001). In both patient groups, the oral health-related quality of life was impaired (42.9/52.7 points; p < 0.001), and the frequency of therapy measures prior to the consultation hour was high. Conclusions Patients seeking care from TMD specialists were usually referred with TMD-associated symptoms. Of those, a relevant proportion did not receive a diagnosis according to RDC/TMD decision trees. Clinical relevance Psychosocial screening and the avoidance of overtreatment are recommended for patients with TMD-related symptoms.

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